Protein name:
Interleukin-11 (IL-11) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
Subcellular Location:
Secreted
Protein Attributes:
50:
MNCVCRLVLV | VLSLWPDRVV | APGPPAGSPR | VSSDPRADLD | SAVLLTRSLL |
100:
ADTRQLAAQM | RDKFPADGDH | SLDSLPTLAM | SAGTLGSLQL | PGVLTRLRVD |
150:
LMSYLRHVQW | LRRAGGPSLK | TLEPELGALQ | ARLERLLRRL | QLLMSRLALP |
199:
QAAPDQPVIP | LGPPASAWGS | IRAAHAILGG | LHLTLDWAVR | GLLLLKTRL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Mouse IL-11
ELISA Kit for Mouse IL-11
ELISA Kit for Mouse IL-11
Polyclonal Antibody for Mouse IL-11
Polyclonal Antibody for Mouse IL-11
Polyclonal Antibody for Mouse IL-11
Monoclonal Antibody for Mouse IL-11
Monoclonal Antibody for Mouse IL-11
Monoclonal Antibody for Mouse IL-11
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;MUTAGENESIS OF TRP-168; ARG-172; ARG-190 AND LEU-193
3.
"Interleukin-11 links oxidative stress and compensatory proliferation."
Nishina T.
,
Komazawa-Sakon S.
,
Yanaka S.
,
Piao X.
,
Zheng D.M.
,
Piao J.H.
,
Kojima Y.
,
Yamashina S.
,
Sano E.
,
Putoczki T.
,
Doi T.
,
Ueno T.
,
Ezaki J.
,
Ushio H.
,
Ernst M.
,
Tsumoto K.
,
Okumura K.
,
Nakano H.
Sci. Signal.5:RA5-RA5(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INDUCTION BY OXIDATIVE STRESS
4.
"Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically."
Putoczki T.L.
,
Thiem S.
,
Loving A.
,
Busuttil R.A.
,
Wilson N.J.
,
Ziegler P.K.
,
Nguyen P.M.
,
Preaudet A.
,
Farid R.
,
Edwards K.M.
,
Boglev Y.
,
Luwor R.B.
,
Jarnicki A.
,
Horst D.
,
Boussioutas A.
,
Heath J.K.
,
Sieber O.M.
,
Pleines I.
,
Kile B.T.
,
Nash A.
,
Greten F.R.
,
McKenzie B.S.
,
Ernst M.
more...
Cancer Cell24:257-271(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION