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Index > Protein center > LAMA1(Gene name) > Human
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  • LAMA1 (Gene name),
  • Laminin subunit alpha-1 (Protein name ),  LAMA1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    LAMA1(LAMA);
    Protein name:
    Laminin subunit alpha-1;
    Alternative:
    Laminin-1 subunit alpha;Laminin A chain;S-laminin subunit alpha(S-LAM alpha);Laminin-3 subunit alpha;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-1 is a subunit of laminin-1 (laminin-111 or EHS laminin) and laminin-3 (laminin-121 or S-laminin).
    Function:
    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
    Subcellular Location:
    Secreted extracellular space extracellular matrix basement membrane Major component.
    Protein Attributes:
    Sequence length:
    3075
    Sequence:
    50:
    MRGGVLLVLL | LCVAAQCRQR | GLFPAILNLA | SNAHISTNAT | CGEKGPEMFC | 
    100:
    KLVEHVPGRP | VRNPQCRICD | GNSANPRERH | PISHAIDGTN | NWWQSPSIQN | 
    150:
    GREYHWVTIT | LDLRQVFQVA | YVIIKAANAP | RPGNWILERS | LDGTTFSPWQ | 
    200:
    YYAVSDSECL | SRYNITPRRG | PPTYRADDEV | ICTSYYSRLV | PLEHGEIHTS | 
    250:
    LINGRPSADD | LSPKLLEFTS | ARYIRLRLQR | IRTLNADLMT | LSHREPKELD | 
    300:
    PIVTRRYYYS | IKDISVGGMC | ICYGHASSCP | WDETTKKLQC | QCEHNTCGES | 
    350:
    CNRCCPGYHQ | QPWRPGTVSS | GNTCEACNCH | NKAKDCYYDE | SVAKQKKSLN | 
    400:
    TAGQFRGGGV | CINCLQNTMG | INCETCIDGY | YRPHKVSPYE | DEPCRPCNCD | 
    450:
    PVGSLSSVCI | KDDLHSDLHN | GKQPGQCPCK | EGYTGEKCDR | CQLGYKDYPT | 
    500:
    CVSCGCNPVG | SASDEPCTGP | CVCKENVEGK | ACDRCKPGFY | NLKEKNPRGC | 
    550:
    SECFCFGVSD | VCSSLSWPVG | QVNSMSGWLV | TDLISPRKIP | SQQDALGGRH | 
    600:
    QVSINNTAVM | QRLAPKYYWA | APEAYLGNKL | TAFGGFLKYT | VSYDIPVETV | 
    650:
    DSNLMSHADV | IIKGNGLTLS | TQAEGLSLQP | YEEYLNVVRL | VPENFQDFHS | 
    700:
    KRQIDRDQLM | TVLANVTHLL | IRANYNSAKM | ALYRLESVSL | DIASSNAIDL | 
    750:
    VVAADVEHCE | CPQGYTGTSC | ESCLSGYYRV | DGILFGGICQ | PCECHGHAAE | 
    800:
    CNVHGVCIAC | AHNTTGVHCE | QCLPGFYGEP | SRGTPGDCQP | CACPLTIASN | 
    850:
    NFSPTCHLND | GDEVVCDWCA | PGYSGAWCER | CADGYYGNPT | VPGESCVPCD | 
    900:
    CSGNVDPSEA | GHCDSVTGEC | LKCLGNTDGA | HCERCADGFY | GDAVTAKNCR | 
    950:
    ACECHVKGSH | SAVCHLETGL | CDCKPNVTGQ | QCDQCLHGYY | GLDSGHGCRP | 
    1000:
    CNCSVAGSVS | DGCTDEGQCH | CVPGVAGKRC | DRCAHGFYAY | QDGSCTPCDC | 
    1050:
    PHTQNTCDPE | TGECVCPPHT | QGVKCEECED | GHWGYDAEVG | CQACNCSLVG | 
    1100:
    STHHRCDVVT | GHCQCKSKFG | GRACDQCSLG | YRDFPDCVPC | DCDLRGTSGD | 
    1150:
    ACNLEQGLCG | CVEETGACPC | KENVFGPQCN | ECREGTFALR | ADNPLGCSPC | 
    1200:
    FCSGLSHLCS | ELEDYVRTPV | TLGSDQPLLR | VVSQSNLRGT | TEGVYYQAPD | 
    1250:
    FLLDAATVRQ | HIRAEPFYWR | LPQQFQGDQL | MAYGGKLKYS | VAFYSLDGVG | 
    1300:
    TSNFEPQVLI | KGGRIRKQVI | YMDAPAPENG | VRQEQEVAMR | ENFWKYFNSV | 
    1350:
    SEKPVTREDF | MSVLSDIEYI | LIKASYGQGL | QQSRISDISM | EVGRKAEKLH | 
    1400:
    PEEEVASLLE | NCVCPPGTVG | FSCQDCAPGY | HRGKLPAGSD | RGPRPLVAPC | 
    1450:
    VPCSCNNHSD | TCDPNTGKCL | NCGDNTAGDH | CDVCTSGYYG | KVTGSASDCA | 
    1500:
    LCACPHSPPA | SFSPTCVLEG | DHDFRCDACL | LGYEGKHCER | CSSSYYGNPQ | 
    1550:
    TPGGSCQKCD | CNPHGSVHGD | CDRTSGQCVC | RLGASGLRCD | ECEPRHILME | 
    1600:
    TDCVSCDDEC | VGVLLNDLDE | IGDAVLSLNL | TGIIPVPYGI | LSNLENTTKY | 
    1650:
    LQESLLKENM | QKDLGKIKLE | GVAEETDNLQ | KKLTRMLAST | QKVNRATERI | 
    1700:
    FKESQDLAIA | IERLQMSITE | IMEKTTLNQT | LDEDFLLPNS | TLQNMQQNGT | 
    1750:
    SLLEIMQIRD | FTQLHQNATL | ELKAAEDLLS | QIQENYQKPL | EELEVLKEAA | 
    1800:
    SHVLSKHNNE | LKAAEALVRE | AEAKMQESNH | LLLMVNANLR | EFSDKKLHVQ | 
    1850:
    EEQNLTSELI | VQGRGLIDAA | AAQTDAVQDA | LEHLEDHQDK | LLLWSAKIRH | 
    1900:
    HIDDLVMHMS | QRNAVDLVYR | AEDHAAEFQR | LADVLYSGLE | NIRNVSLNAT | 
    1950:
    SAAYVHYNIQ | SLIEESEELA | RDAHRTVTET | SLLSESLVSN | GKAAVQRSSR | 
    2000:
    FLKEGNNLSR | KLPGIALELS | ELRNKTNRFQ | ENAVEITRQT | NESLLILRAI | 
    2050:
    PKGIRDKGAK | TKELATSASQ | SAVSTLRDVA | GLSQELLNTS | ASLSRVNTTL | 
    2100:
    RETHQLLQDS | TMATLLAGRK | VKDVEIQANL | LFDRLKPLKM | LEENLSRNLS | 
    2150:
    EIKLLISQAR | KQAASIKVAV | SADRDCIRAY | QPQISSTNYN | TLTLNVKTQE | 
    2200:
    PDNLLFYLGS | STASDFLAVE | MRRGRVAFLW | DLGSGSTRLE | FPDFPIDDNR | 
    2250:
    WHSIHVARFG | NIGSLSVKEM | SSNQKSPTKT | SKSPGTANVL | DVNNSTLMFV | 
    2300:
    GGLGGQIKKS | PAVKVTHFKG | CLGEAFLNGK | SIGLWNYIER | EGKCRGCFGS | 
    2350:
    SQNEDPSFHF | DGSGYSVVEK | SLPATVTQII | MLFNTFSPNG | LLLYLGSYGT | 
    2400:
    KDFLSIELFR | GRVKVMTDLG | SGPITLLTDR | RYNNGTWYKI | AFQRNRKQGV | 
    2450:
    LAVIDAYNTS | NKETKQGETP | GASSDLNRLD | KDPIYVGGLP | RSRVVRRGVT | 
    2500:
    TKSFVGCIKN | LEISRSTFDL | LRNSYGVRKG | CLLEPIRSVS | FLKGGYIELP | 
    2550:
    PKSLSPESEW | LVTFATTNSS | GIILAALGGD | VEKRGDREEA | HVPFFSVMLI | 
    2600:
    GGNIEVHVNP | GDGTGLRKAL | LHAPTGTCSD | GQAHSISLVR | NRRIITVQLD | 
    2650:
    ENNPVEMKLG | TLVESRTINV | SNLYVGGIPE | GEGTSLLTMR | RSFHGCIKNL | 
    2700:
    IFNLELLDFN | SAVGHEQVDL | DTCWLSERPK | LAPDAEDSKL | LPEPRAFPEQ | 
    2750:
    CVVDAALEYV | PGAHQFGLTQ | NSHFILPFNQ | SAVRKKLSVE | LSIRTFASSG | 
    2800:
    LIYYMAHQNQ | ADYAVLQLHG | GRLHFMFDLG | KGRTKVSHPA | LLSDGKWHTV | 
    2850:
    KTDYVKRKGF | ITVDGRESPM | VTVVGDGTML | DVEGLFYLGG | LPSQYQARKI | 
    2900:
    GNITHSIPAC | IGDVTVNSKQ | LDKDSPVSAF | TVNRCYAVAQ | EGTYFDGSGY | 
    2950:
    AALVKEGYKV | QSDVNITLEF | RTSSQNGVLL | GISTAKVDAI | GLELVDGKVL | 
    3000:
    FHVNNGAGRI | TAAYEPKTAT | VLCDGKWHTL | QANKSKHRIT | LIVDGNAVGA | 
    3050:
    ESPHTQSTSV | DTNNPIYVGG | YPAGVKQKCL | RSQTSFRGCL | RKLALIKSPQ | 
    3075:
    VQSFDFSRAF | ELHGVFLHSC | PGTES
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Laminin subunit alpha-1
    Cat.:
    E0082m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Laminin subunit alpha-1
    Cat.:
    E0082h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Laminin subunit alpha-1
    Cat.:
    U0082m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Laminin subunit alpha-1
    Cat.:
    U0082h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Laminin subunit alpha-1
    Cat.:
    P0082Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Laminin subunit alpha-1
    Cat.:
    P0082Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Laminin subunit alpha-1
    Monoclonal Antibody for Human Laminin subunit alpha-1
    Protein for Human Laminin subunit alpha-1
    Protein for Human Laminin subunit alpha-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning of the cDNA encoding human laminin A chain."
      Haaparanta T. , Uitto J. , Ruoslahti E. , Engvall E.
      Matrix11:151-160(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS THR-674; VAL-1340; THR-1876 AND GLU-2002
    2. 3.
      "Primary structure of the human laminin A chain. Limited expression in human tissues."
      Nissinen M. , Vuolteenaho R. , Boot-Handford R. , Kallunki P. , Tryggvason K.
      Biochem. J.276:369-379(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-2628;VARIANTS THR-674; THR-1876 AND GLU-2002
    3. 4.
      "Human laminin: cloning and sequence analysis of cDNAs encoding A, B1 and B2 chains, and expression of the corresponding genes in human skin and cultured cells."
      Olsen D. , Nagayoshi T. , Fazio M. , Peltonen J. , Jaakkola S. , Sanborn D. , Sasaki T. , Kuivaniemi H. , Chu M.-L. , Deutzmann R. , Timpl R. , Uitto J.
      Lab. Invest.60:772-782(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2397-3072
    4. 5.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-2243
      tissue: Liver.
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION
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