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Index > Protein center > Qki(Gene name) > Rat
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  • Qki (Gene name),
  • Protein quaking (Protein name ),  QKI_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Qki(Qk);
    Protein name:
    Protein quaking(RqkI);
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer. Does not require RNA to homodimerize. Able to heterodimerize with BICC1.
    Function:
    RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor.
    Subcellular Location:
    Nucleus Cytoplasm
    Protein Attributes:
    Sequence length:
    341
    Sequence:
    50:
    MVGEMETKEN | PNPTPDYLMQ | LMNDKKLMSS | LPNFCGIFNH | LERLLDEEIS | 
    100:
    RVRKDMYNDT | LNGSTEKRSA | ELPDAVGPIV | QLQEKLYVPV | KEYPDFNFVG | 
    150:
    RILGPRGLTA | KQLEAETGCK | IMVRGKGSMR | DKKKEEQNRG | KPNWEHLNED | 
    200:
    LHVLITVEDA | QNRAEIKLKR | AVEEVKKLLV | PAAEGEDSLK | KMQLMELAIL | 
    250:
    NGTYRDANIK | SPALAFSLAA | TAQAAPRIIT | GPAPVLPPAA | LRTPTPAGPT | 
    300:
    IMPLIRQIQT | AVMPNGTPHP | TAAIVPPGPE | AGLIYTPYEY | PYTLAPATSI | 
    341:
    LEYPIEPSGV | LGAVATKVRR | HDMRVHPYQR | IVTADRAATG | N
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    Pfam:
    UniGene:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat RqkI
    ELISA Kit for Rat RqkI
    ELISA Kit for Rat RqkI
    ELISA Kit for Rat RqkI
    ELISA Kit for Rat RqkI
    ELISA Kit for Rat RqkI
    ELISA Kit for Rat RqkI
    CLIA Kit for Rat RqkI
    CLIA Kit for Rat RqkI
    CLIA Kit for Rat RqkI
    CLIA Kit for Rat RqkI
    CLIA Kit for Rat RqkI
    CLIA Kit for Rat RqkI
    CLIA Kit for Rat RqkI
    Polyclonal Antibody for Rat RqkI
    Polyclonal Antibody for Rat RqkI
    Polyclonal Antibody for Rat RqkI
    Polyclonal Antibody for Rat RqkI
    Polyclonal Antibody for Rat RqkI
    Polyclonal Antibody for Rat RqkI
    Polyclonal Antibody for Rat RqkI
    Monoclonal Antibody for Rat RqkI
    Monoclonal Antibody for Rat RqkI
    Monoclonal Antibody for Rat RqkI
    Monoclonal Antibody for Rat RqkI
    Monoclonal Antibody for Rat RqkI
    Monoclonal Antibody for Rat RqkI
    Monoclonal Antibody for Rat RqkI
    Protein for Rat RqkI
    Protein for Rat RqkI
    Protein for Rat RqkI
    Protein for Rat RqkI
    Protein for Rat RqkI
    Protein for Rat RqkI
    Protein for Rat RqkI

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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "Differentially expressed genes."
      Leng S. , Tsutsumi M. , Takase S. , Abe S. , Yamamoto Y. , Fukunaga T. , Saijoh K.
      Submitted (2001-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 98-302
      tissue: Brain.
    3. 3.
      "Expression of QKI proteins and MAP1B identifies actively myelinating oligodendrocytes in adult rat brain."
      Wu H.Y. , Dawson M.R.L. , Reynolds R. , Hardy R.J.
      Mol. Cell. Neurosci.17:292-302(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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