S100B ELISA Kit for Human(Homo sapiens) | EIAab.comS100B ELISA Kit for Human(Homo sapiens)

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Index > Protein center > S100B(Gene name) > Human

S100B (Gene name),

Protein S100-B (Protein name ), S100B_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

S100B;

Protein name:

Protein S100-B;

Alternative:

S-100 protein subunit beta;S-100 protein beta chain;S100 calcium-binding protein B;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. The S100B dimer binds two molecules of STK38. Interacts with AGER (By similarity). The S100B dimer interacts with two molecules of CAPZA1.

Function:

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

Sequence:

50:

92:

QEVVDKVMET | LDNDGDGECD | FQEFMAFVAM | VTTACHEFFE | HE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:6285

UniGene:

Hs.422181

SMR:

P04271

String:

P04271

STRING:

9606.ENSP00000291700

Pfam:

PF01023

MIM:

176990

Uniprot:

P04271

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ELISA Kit for Human Protein S100-B

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E0567h

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96T

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ELISA Kit for Human Protein S100-B

Cat.:

E0567r

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96T

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ELISA Kit for Human Protein S100-B

Cat.:

E0567m

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96T

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ELISA Kit for Human Protein S100-B

Cat.:

E0567b

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MSDS:

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Packing:

96T

ELISA Kit for Human Protein S100-B

MSDS:

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CLIA Kit for Human Protein S100-B

Cat.:

U0567h

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96T

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CLIA Kit for Human Protein S100-B

Cat.:

U0567m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Protein S100-B

Cat.:

U0567r

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96T

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CLIA Kit for Human Protein S100-B

MSDS:

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CLIA Kit for Human Protein S100-B

Cat.:

U0567b

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Packing:

96T

Polyclonal Antibody for Human Protein S100-B

Cat.:

P0567Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Protein S100-B

Cat.:

P0567Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Protein S100-B

Cat.:

P0567Rb-m

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40ug/0.2ml

Monoclonal Antibody for Human Protein S100-B

Protein for Human Protein S100-B

Cat.:

R0567h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Human Protein S100-B

R&D Technical Data

12% SDS-PAGE analysis

? ? ? ??12% SDS-PAGE analysis

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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Citations

[1].

"S100B Protein, Brain-Derived Neurotrophic Factor, and Glial Cell Line-Derived Neurotrophic Factor in Human Milk"

R Li, W Xia, Z Zhang, K Wu

From:PloS one

References

1.

"Cloning and expression of the human S100 beta gene."
Allore R.J. , Friend W.C. , O'Hanlon D. , Neilson K.M. , Baumal R. , Dunn R.J. , Marks A.
J. Biol. Chem.265:15537-15543(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

"The DNA sequence of human chromosome 21."
Hattori M. , Fujiyama A. , Taylor T.D. , Watanabe H. , Yada T. , Park H.-S. , Toyoda A. , Ishii K. , Totoki Y. , Choi D.-K. , Groner Y. , Soeda E. , Ohki M. , Takagi T. , Sakaki Y. , Taudien S. , Blechschmidt K. , Polley A. , more...
Nature405:311-319(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Skin.
6.

"Characterization of human brain S100 protein fraction: amino acid sequence of S100 beta."
Jensen R. , Marshak D.R. , Anderson C. , Lukas T.J. , Watterson D.M.
J. Neurochem.45:700-705(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-92
7.

"Purification, characterization and ion binding properties of human brain S100b protein."
Baudier J. , Glasser N. , Haglid K. , Gerard D.
Biochim. Biophys. Acta790:164-173(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METAL ION-BINDING PROPERTIES
8.

"Demonstration of heterodimer formation between S100B and S100A6 in the yeast two-hybrid system and human melanoma."
Yang Q. , O'Hanlon D. , Heizmann C.W. , Marks A.
Exp. Cell Res.246:501-509(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH S100A6
9.

"The 1.5 A crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding."
Park H. , Adsit F.G. , Boyington J.C.
J. Biol. Chem.285:40762-40770(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AGER
10.

"The calcium-dependent interaction between S100B and the mitochondrial AAA ATPase ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A."
Gilquin B. , Cannon B.R. , Hubstenberger A. , Moulouel B. , Falk E. , Merle N. , Assard N. , Kieffer S. , Rousseau D. , Wilder P.T. , Weber D.J. , Baudier J.
Mol. Cell. Biol.30:2724-2736(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ATAD3A
11.

"S100 proteins modulate protein phosphatase 5 function: a link between CA2+ signal transduction and protein dephosphorylation."
Yamaguchi F. , Umeda Y. , Shimamoto S. , Tsuchiya M. , Tokumitsu H. , Tokuda M. , Kobayashi R.
J. Biol. Chem.287:13787-13798(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PPP5C
12.

"A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form."
Smith S.P. , Shaw G.S.
Structure6:211-222(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
13.

"A novel S100 target conformation is revealed by the solution structure of the Ca2+-S100B-TRTK-12 complex."
McClintock K.A. , Shaw G.S.
J. Biol. Chem.278:6251-6257(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR IN COMPLEX WITH CAPZA1 AND CALCIUM

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