Tgfb1 ELISA Kit for Mouse(Mus musculus) | EIAab.comTgfb1 ELISA Kit for Mouse(Mus musculus)

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Tgfb1 (Gene name),

Transforming growth factor beta-1 (Protein name ), TGFB1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (4)

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Gene name:

Tgfb1;

Protein name:

Transforming growth factor beta-1(TGF-beta-1);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

The inactive form consists of a TGFB1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The inactive complex can contain a latent TGFB1-binding protein. The active form is a homodimer of mature TGFB1; disulfide-linked. Heterodimers of TGFB1/TGFB2 have been found in bone. Interacts with CD109 and DPT. Interacts with ASPN.

Function:

Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

390

Sequence:

50:

100:

150:

200:

250:

300:

350:

390:

SASPCCVPQA | LEPLPIVYYV | GRKPKVEQLS | NMIVRSCKCS |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00019

KEGG:

mmu:21803

UniGene:

Mm.248380

SMR:

P04202

String:

P04202

STRING:

10090.ENSMUSP00000002678

Uniprot:

P04202

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ELISA Kit for Mouse TGF-beta-1

Cat.:

E0124b

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96T

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ELISA Kit for Mouse TGF-beta-1

Cat.:

E0124h

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96T

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ELISA Kit for Mouse TGF-beta-1

Cat.:

E0124m

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96T

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ELISA Kit for Mouse TGF-beta-1

Cat.:

E0124p

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96T

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ELISA Kit for Mouse TGF-beta-1

Cat.:

E0124d

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MSDS:

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Packing:

96T

ELISA Kit for Mouse TGF-beta-1

Cat.:

E0124c

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96T

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ELISA Kit for Mouse TGF-beta-1

Cat.:

E0124r

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96T

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CLIA Kit for Mouse TGF-beta-1

Cat.:

U0124d

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TGF-beta-1

Cat.:

U0124c

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TGF-beta-1

Cat.:

U0124r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TGF-beta-1

Cat.:

U0124m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse TGF-beta-1

Cat.:

U0124h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse TGF-beta-1

Cat.:

U0124p

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse TGF-beta-1

Cat.:

U0124b

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Mouse TGF-beta-1

Cat.:

P0124Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse TGF-beta-1

Cat.:

P0124Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse TGF-beta-1

Cat.:

P0124Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse TGF-beta-1

Monoclonal Antibody for Mouse TGF-beta-1

Protein for Mouse TGF-beta-1

Cat.:

R0124h

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Packing:

1mg

Purity:

>90%

Protein for Mouse TGF-beta-1

Cat.:

R0124m

Price:

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Packing:

1mg

Purity:

>90%

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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Citations

[1].

"Preconditioning of umbilical cord‐derived mesenchymal stem cells by rapamycin increases cell migration and ameliorates liver ischaemia/reperfusion injury in mice via the CXCR4/CXCL12 axis"

J Zheng, H Li, L Chen, et al.

From:cell proliferation

[2].

"Simvastatin Attenuates Intestinal Fibrosis Independent of the Anti-Inflammatory Effect by Promoting Fibroblast/Myofibroblast Apoptosis"

Y Abe, M Murano, N Murano, et al.

From:Digestive diseases and sciences

[3].

"A Soluble Antigen-Specific Factor from CD4+CD25+ T Cells of OVA Tolerant Mice Inducing OVA-Specific Peripheral Tolerance Independently in vivo"

C.Y. Wu, G.H. Zhao, Y.Q. Zhao, H. Liu, P.J. Zhang and D.K. Chen

From:Journal Of Animal and Veterinary Advances

[4].

"In vitro morphology, viability and cytokine secretion of uterine telocyte-activated mouse peritoneal macrophages"

Chi C, Jiang X J, Su L, et al.

From:Journal of cellular and molecular medicine

References

1.

"The murine transforming growth factor-beta precursor."
Derynck R. , Jarrett J.A. , Chen E.Y. , Goeddel D.V.
J. Biol. Chem.261:4377-4379(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Molecular organization of the gene encoding murine transforming growth factor beta 1."
Guron C. , Sudarshan C. , Raghow R.
Gene165:325-326(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: BALB/c.
3.

"Transforming growth factor-beta 1 sequence and expression: no difference between NOD/Lt and C57Bl/6 mouse strains."
Poirot L. , Benoist C. , Mathis D.
Submitted (1998-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
strain: NOD/LT.
tissue: Spleen.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Mammary tumor.
5.

"P311 binds to the latency associated protein and downregulates the expression of TGF-beta1 and TGF-beta2."
Paliwal S. , Shi J. , Dhru U. , Zhou Y. , Schuger L.
Biochem. Biophys. Res. Commun.315:1104-1109(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NREP
6.

"Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling."
Tocharus J. , Tsuchiya A. , Kajikawa M. , Ueta Y. , Oka C. , Kawaichi M.
Dev. Growth Differ.46:257-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTRA3
7.

"HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins."
Oka C. , Tsujimoto R. , Kajikawa M. , Koshiba-Takeuchi K. , Ina J. , Yano M. , Tsuchiya A. , Ueta Y. , Soma A. , Kanda H. , Matsumoto M. , Kawaichi M.
Development131:1041-1053(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTRA1
8.

"ADAMTSL6beta protein rescues fibrillin-1 microfibril disorder in a Marfan syndrome mouse model through the promotion of fibrillin-1 assembly."
Saito M. , Kurokawa M. , Oda M. , Oshima M. , Tsutsui K. , Kosaka K. , Nakao K. , Ogawa M. , Manabe R. , Suda N. , Ganjargal G. , Hada Y. , Noguchi T. , Teranaka T. , Sekiguchi K. , Yoneda T. , Tsuji T.
J. Biol. Chem.286:38602-38613(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH THSD4
9.

"Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-? pathway."
Bruce D.L. , Macartney T. , Yong W. , Shou W. , Sapkota G.P.
Cell. Signal.24:1999-2006(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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