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Index > Protein center > TIMP1(Gene name) > Dog
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  • TIMP1 (Gene name),
  • Metalloproteinase inhibitor 1 (Protein name ),  TIMP1_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    TIMP1;
    Protein name:
    Metalloproteinase inhibitor 1;
    Alternative:
    Tissue inhibitor of metalloproteinases 1(TIMP-1);
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    207
    Sequence:
    50:
    MAPFAPLASC | ILLLLWVTAP | SRACTCAPPH | PQTALCNSQI | VIRAKFVGTA | 
    100:
    EVNQTDLNRR | YEIKMTKMFK | GFSALGNASD | IRFVDTPALE | SVCGYLHRSQ | 
    150:
    NRSEEFLVAG | NLRDGHLQIN | TCSFVAPWSS | LSTAQRRGFT | KTYAAGCEGC | 
    200:
    TVFTCSSIPC | KLQSDTHCLW | TDHFLTGSDK | GFQSRHLACL | PREPGICTWQ | 
    207:
    SLRPRMA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    E0552m
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    Packing:
    96T
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    ELISA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    E0552r
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    96T
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    ELISA Kit for Dog Metalloproteinase inhibitor 1
    MSDS:
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    ELISA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    E0552p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    E0552b
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    MSDS:
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    96T
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    ELISA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    E0552d
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    96T
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    ELISA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    E0552h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    U0552r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog Metalloproteinase inhibitor 1
    MSDS:
    Please sign in first.
    CLIA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    U0552d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    U0552p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    U0552h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    U0552b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Metalloproteinase inhibitor 1
    Cat.:
    U0552m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Dog Metalloproteinase inhibitor 1
    Cat.:
    P0552Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Metalloproteinase inhibitor 1
    Polyclonal Antibody for Dog Metalloproteinase inhibitor 1
    Cat.:
    P0552Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Metalloproteinase inhibitor 1
    Polyclonal Antibody for Dog Metalloproteinase inhibitor 1
    Polyclonal Antibody for Dog Metalloproteinase inhibitor 1
    Polyclonal Antibody for Dog Metalloproteinase inhibitor 1
    Cat.:
    P0552Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Dog Metalloproteinase inhibitor 1
    Monoclonal Antibody for Dog Metalloproteinase inhibitor 1
    Monoclonal Antibody for Dog Metalloproteinase inhibitor 1
    Monoclonal Antibody for Dog Metalloproteinase inhibitor 1
    Monoclonal Antibody for Dog Metalloproteinase inhibitor 1
    Monoclonal Antibody for Dog Metalloproteinase inhibitor 1
    Monoclonal Antibody for Dog Metalloproteinase inhibitor 1
    Protein for Dog Metalloproteinase inhibitor 1
    Protein for Dog Metalloproteinase inhibitor 1
    Protein for Dog Metalloproteinase inhibitor 1
    Protein for Dog Metalloproteinase inhibitor 1
    Protein for Dog Metalloproteinase inhibitor 1
    Protein for Dog Metalloproteinase inhibitor 1
    Cat.:
    R0552h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Dog Metalloproteinase inhibitor 1
    Cat.:
    R0552m
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

    R&D Technical Data
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              12% SDS-PAGE Analysis

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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 5.8%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 8.9%

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    Recovery
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    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    92-105

    Plasma

    98

    91-106

     

     

     

     

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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    90-103%

    91-104%

    94-102%

    92-105%

    EDTA plasma(n=5)

    91-97%

    93-102%

    89-105%

    91-106%

    heparin plasma(n=5)

    92-104%

     

    94-108%

    95-109%

    91-107%

     

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    References
    1. 1.
      "Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in metastatic MDCK cells transformed by v-src."
      Noritake H. , Miyamori H. , Goto C. , Seiki M. , Sato H.
      Clin. Exp. Metastasis17:105-110(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Cocker spaniel.
      tissue: Kidney.
    2. 2.
      "TIMP-1 expression is increased in X-linked progressive retinal atrophy despite its exclusion as a candidate gene."
      Zeiss C.J. , Acland G.M. , Aguirre G.D. , Ray K.
      Gene225:67-75(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    3. 3.
      "Purification of recombinant dog tissue inhibitor of metalloproteinases."
      Chopra R. , Koklitis P.A. , Bergin S. , Rowe J. , Angal S.
      Biochem. Soc. Trans.19:372S-372S(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
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