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Index > Protein center > Timp3(Gene name) > Mouse
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  • Timp3 (Gene name),
  • Metalloproteinase inhibitor 3 (Protein name ),  TIMP3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Timp3(Sun;Timp-3);
    Protein name:
    Metalloproteinase inhibitor 3;
    Alternative:
    Tissue inhibitor of metalloproteinases 3(TIMP-3);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with EFEMP1.
    Function:
    Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    211
    Sequence:
    50:
    MTPWLGLVVL | LSCWSLGHWG | AEACTCSPSH | PQDAFCNSDI | VIRAKVVGKK | 
    100:
    LVKEGPFGTL | VYTIKQMKMY | RGFSKMPHVQ | YIHTEASESL | CGLKLEVNKY | 
    150:
    QYLLTGRVYE | GKMYTGLCNF | VERWDHLTLS | QRKGLNYRYH | LGCNCKIKSC | 
    200:
    YYLPCFVTSK | NECLWTDMLS | NFGYPGYQSK | HYACIRQKGG | YCSWYRGWAP | 
    211:
    PDKSISNATD | P
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    SMR:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Metalloproteinase inhibitor 3
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    ELISA Kit for Mouse Metalloproteinase inhibitor 3
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    E0129b
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    ELISA Kit for Mouse Metalloproteinase inhibitor 3
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    E0129c
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    ELISA Kit for Mouse Metalloproteinase inhibitor 3
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    ELISA Kit for Mouse Metalloproteinase inhibitor 3
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    CLIA Kit for Mouse Metalloproteinase inhibitor 3
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    U0129b
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    CLIA Kit for Mouse Metalloproteinase inhibitor 3
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    U0129h
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    CLIA Kit for Mouse Metalloproteinase inhibitor 3
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    U0129r
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    CLIA Kit for Mouse Metalloproteinase inhibitor 3
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    CLIA Kit for Mouse Metalloproteinase inhibitor 3
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    CLIA Kit for Mouse Metalloproteinase inhibitor 3
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    U0129c
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    Polyclonal Antibody for Mouse Metalloproteinase inhibitor 3
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    P0129Rb-m
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    Packing:
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    Polyclonal Antibody for Mouse Metalloproteinase inhibitor 3
    Polyclonal Antibody for Mouse Metalloproteinase inhibitor 3
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    P0129Rb-r
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    Polyclonal Antibody for Mouse Metalloproteinase inhibitor 3
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    P0129Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Metalloproteinase inhibitor 3
    Polyclonal Antibody for Mouse Metalloproteinase inhibitor 3
    Monoclonal Antibody for Mouse Metalloproteinase inhibitor 3
    Monoclonal Antibody for Mouse Metalloproteinase inhibitor 3
    Monoclonal Antibody for Mouse Metalloproteinase inhibitor 3
    Monoclonal Antibody for Mouse Metalloproteinase inhibitor 3
    Monoclonal Antibody for Mouse Metalloproteinase inhibitor 3
    Monoclonal Antibody for Mouse Metalloproteinase inhibitor 3
    Protein for Mouse Metalloproteinase inhibitor 3
    Protein for Mouse Metalloproteinase inhibitor 3
    Protein for Mouse Metalloproteinase inhibitor 3
    Protein for Mouse Metalloproteinase inhibitor 3
    Protein for Mouse Metalloproteinase inhibitor 3
    Protein for Mouse Metalloproteinase inhibitor 3

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    References
    1. 1.
      "Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues."
      Leco K.J. , Khokha R. , Pavloff N. , Hawkes S.P. , Edwards D.R.
      J. Biol. Chem.269:9352-9360(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Molecular cloning of five messenger RNAs differentially expressed in preneoplastic or neoplastic JB6 mouse epidermal cells: one is homologous to human tissue inhibitor of metalloproteinases-3."
      Sun Y. , Hegamyer G. , Colburn N.H.
      Cancer Res.54:1139-1144(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: BALB/c.
      tissue: Lung.
      tissue: Skin.
    3. 3.
      "Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP-3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10."
      Apte S.S. , Hayashi K. , Seldin M.F. , Mattei M.-G. , Hayashi M. , Olsen B.R.
      Dev. Dyn.200:177-197(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lung.
    4. 4.
      "Molecular cloning of mouse tissue inhibitor of metalloproteinases-3 and its promoter. Specific lack of expression in neoplastic JB6 cells may reflect altered gene methylation."
      Sun Y. , Hegamyer G. , Kim H. , Sithanandam K. , Li H. , Watts R. , Colburn N.H.
      J. Biol. Chem.270:19312-19319(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family."
      Apte S.S. , Olsen B.R. , Murphy G.
      J. Biol. Chem.270:14313-14318(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/Sv.
    6. 6.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Spinal ganglion.
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Kidney.
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