Tlr2 ELISA Kit for Mouse(Mus musculus) | EIAab.comTlr2 ELISA Kit for Mouse(Mus musculus)

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Tlr2 (Gene name),

Toll-like receptor 2 (Protein name ), TLR2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

Tlr2;

Protein name:

Toll-like receptor 2;

Alternative:

CD:

CD282;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with LY96, TLR1 and TLR6 (via extracellular domain). Binds MYD88 (via TIR domain). Interacts with TICAM1. Ligand binding induces the formation of a heterodimer with TLR1 (By similarity). Interacts with CNPY3.

Function:

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Cytoplasmic vesicle phagosome membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

784

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

784:

KLRKIMNTKT | YLEWPLDEGQ | QEVFWVNLRT | AIKS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.87596

STRING:

10090.ENSMUSP00000029623

String:

Q9QUN7

SMR:

Q9QUN7

KEGG:

mmu:24088

Pfam:

PF01582

Pfam:

PF00560

Uniprot:

Q9QUN7

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ELISA Kit for Mouse Toll-like receptor 2

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E0663h

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96T

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ELISA Kit for Mouse Toll-like receptor 2

Cat.:

E0663m

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96T

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ELISA Kit for Mouse Toll-like receptor 2

Cat.:

E0663d

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96T

ELISA Kit for Mouse Toll-like receptor 2

Cat.:

E0663b

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96T

CLIA Kit for Mouse Toll-like receptor 2

Cat.:

U0663b

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96T

CLIA Kit for Mouse Toll-like receptor 2

Cat.:

U0663d

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Toll-like receptor 2

Cat.:

U0663m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Toll-like receptor 2

Cat.:

U0663h

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Packing:

96T

Polyclonal Antibody for Mouse Toll-like receptor 2

Cat.:

P0663Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Toll-like receptor 2

Cat.:

P0663Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Toll-like receptor 2

Monoclonal Antibody for Mouse Toll-like receptor 2

Protein for Mouse Toll-like receptor 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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Citations

[1].

"Development of a Porcine Bladder Acellular Matrix with Well-Preserved Extracellular Bioactive Factors for Tissue Engineering"

Bin Yang, Yifen Zhang, Liuhua Zhou, Zeyu Sun,Junhua Zheng, Yun Chen, and Yutian Dai,

From:TISSUE ENGINEERING

References

1.

"The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens."
Underhill D.M. , Ozinsky A. , Hajjar A.M. , Stevens A. , Wilson C.B. , Bassetti M. , Aderem A.
Nature401:811-815(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];MUTAGENESIS OF PRO-681
2.

"Cells that carry a null allele for Toll-like receptor 2 are capable of responding to endotoxin."
Heine H. , Kirschning C.J. , Lien E. , Monks B.G. , Rothe M. , Golenbock D.T.
J. Immunol.162:6971-6975(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Macrophage.
3.

"Gene expressions of lipopolysaccharide receptors, Toll-like receptors 2 and 4, are differently regulated in mouse T lymphocytes."
Matsuguchi T. , Takagi K. , Musikacharoen T. , Yoshikai Y.
Blood95:1378-1385(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Macrophage.
4.

"The lipopolysaccharide-activated Toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes."
Lin Y. , Lee H. , Berg A.H. , Lisanti M.P. , Shapiro L. , Scherer P.E.
J. Biol. Chem.275:24255-24263(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Adipocyte.
5.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
strain: NOD.
tissue: Liver.
6.

Lubec G. , Kang S.U.
Submitted (2007-04) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 405-413 AND 754-759;IDENTIFICATION BY MASS SPECTROMETRY
strain: C57BL/6.
tissue: Brain.
7.

"A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors."
Kiyokawa T. , Akashi-Takamura S. , Shibata T. , Matsumoto F. , Nishitani C. , Kuroki Y. , Seto Y. , Miyake K.
Int. Immunol.20:1407-1415(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CNPY3
8.

"Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide."
Jin M.S. , Kim S.E. , Heo J.Y. , Lee M.E. , Kim H.M. , Paik S.-G. , Lee H. , Lee J.-O.
Cell130:1071-1082(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 27-506;DISULFIDE BONDS;GLYCOSYLATION AT ASN-147; ASN-414 AND ASN-442
9.

"Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer."
Kang J.Y. , Nan X. , Jin M.S. , Youn S.J. , Ryu Y.H. , Mah S. , Han S.H. , Lee H. , Paik S.G. , Lee J.O.
Immunity31:873-884(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 1-506 IN COMPLEX WITH TLR6 AND LIPOPEPTIDE;DISULFIDE BONDS;GLYCOSYLATION AT ASN-147; ASN-414 AND ASN-442;FUNCTION;LRR REPEATS;SUBUNIT

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