Gene name:
TNFSF14 (UNQ391/PRO726;HVEML;LIGHT) ;
Protein name:
Tumor necrosis factor ligand superfamily member 14 ;
Alternative:
Herpes virus entry mediator ligand (HVEM-L;Herpesvirus entry mediator ligand) ;
CD:
CD258 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
Subcellular Location:
Isoform 2
Cytoplasm
Protein Attributes:
50:
MEESVVRPSV | FVVDGQTDIP | FTRLGRSHRR | QSCSVARVGL | GLLLLLMGAG |
100:
LAVQGWFLLQ | LHWRLGEMVT | RLPDGPAGSW | EQLIQERRSH | EVNPAAHLTG |
150:
ANSSLTGSGG | PLLWETQLGL | AFLRGLSYHD | GALVVTKAGY | YYIYSKVQLG |
200:
GVGCPLGLAS | TITHGLYKRT | PRYPEELELL | VSQQSPCGRA | TSSSRVWWDS |
240:
SFLGGVVHLE | AGEKVVVRVL | DERLVRLRDG | TRSYFGAFMV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Tumor necrosis factor ligand superfamily member 14
ELISA Kit for Human Tumor necrosis factor ligand superfamily member 14
CLIA Kit for Human Tumor necrosis factor ligand superfamily member 14
CLIA Kit for Human Tumor necrosis factor ligand superfamily member 14
Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 14
Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 14
Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 14
Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 14
Protein for Human Tumor necrosis factor ligand superfamily member 14
Protein for Human Tumor necrosis factor ligand superfamily member 14
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT GLU-214
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);CHARACTERIZATION
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Liver .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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tissue :
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLU-214
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT GLU-214
9.
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Cited for : X-RAY CRYSTALLOGRAPHY (2.59 ANGSTROMS) OF 83-240;GLYCOSYLATION AT ASN-102;DISULFIDE BOND