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Index > Protein center > TNFSF15(Gene name) > Human
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  • TNFSF15 (Gene name),
  • Tumor necrosis factor ligand superfamily member 15 (Protein name ),  TNF15_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TNFSF15(TL1;VEGI);
    Protein name:
    Tumor necrosis factor ligand superfamily member 15;
    Alternative:
    Vascular endothelial cell growth inhibitor;TNF ligand-related molecule 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer.
    Function:
    Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
    Subcellular Location:
    Tumor necrosis factor ligand superfamily member 15, secreted form Secreted
    Protein Attributes:
    Sequence length:
    251
    Sequence:
    50:
    MAEDLGLSFG | ETASVEMLPE | HGSCRPKARS | SSARWALTCC | LVLLPFLAGL | 
    100:
    TTYLLVSQLR | AQGEACVQFQ | ALKGQEFAPS | HQQVYAPLRA | DGDKPRAHLT | 
    150:
    VVRQTPTQHF | KNQFPALHWE | HELGLAFTKN | RMNYTNKFLL | IPESGDYFIY | 
    200:
    SQVTFRGMTS | ECSEIRQAGR | PNKPDSITVV | ITKVTDSYPE | PTQLLMGTKS | 
    250:
    VCEVGSNWFQ | PIYLGAMFSL | QEGDKLMVNV | SDISLVDYTK | EDKTFFGAFL | 
    251:
    L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    MIM:
    SMR:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tumor necrosis factor ligand superfamily member 15
    Cat.:
    E15371h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Tumor necrosis factor ligand superfamily member 15
    Cat.:
    E15371m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Tumor necrosis factor ligand superfamily member 15
    Cat.:
    E15371r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor ligand superfamily member 15
    Cat.:
    U15371h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor ligand superfamily member 15
    Cat.:
    U15371r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor ligand superfamily member 15
    Cat.:
    U15371m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 15
    Cat.:
    P15371Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 15
    Cat.:
    P15371Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 15
    Cat.:
    P15371Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 15
    Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 15
    Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 15
    Protein for Human Tumor necrosis factor ligand superfamily member 15
    Protein for Human Tumor necrosis factor ligand superfamily member 15
    Protein for Human Tumor necrosis factor ligand superfamily member 15

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    Precision
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    Linearity
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    References
    1. 1.
      "VEGI, a novel cytokine of the tumor necrosis factor family, is an angiogenesis inhibitor that suppresses the growth of colon carcinomas in vivo."
      Zhai Y. , Ni J. , Jiang G.-W. , Lu J. , Xing L. , Lincoln C. , Carter K.C. , Janat F. , Kozak D. , Xu S. , Rojas L. , Aggarwal B.B. , Ruben S. , Li L.-Y. , Gentz R. , Yu G.-L.
      FASEB J.13:181-189(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);FUNCTION;TISSUE SPECIFICITY
      tissue: Umbilical vein.
    2. 2.
      "A novel secreted splice variant of vascular endothelial cell growth inhibitor."
      Chew L.-J. , Pan H. , Yu J. , Tian S. , Huang W.-Q. , Zhang J.Y. , Pang S. , Li L.-Y.
      FASEB J.16:742-744(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF N-TERMINUS;FUNCTION;INTERACTION WITH TNFRSF25 AND TNFRSF6B;SUBCELLULAR LOCATION;PROTEOLYTIC PROCESSING;INDUCTION;TISSUE SPECIFICITY
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    5. 5.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    8. 8.
      "Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells."
      Tan K.B. , Harrop J. , Reddy M. , Young P. , Terrett J. , Emery J. , Moore G. , Truneh A.
      Gene204:35-46(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION (ISOFORM 3);TISSUE SPECIFICITY
    9. 9.
      "VEGI, a new member of the TNF family activates nuclear factor-kappa B and c-Jun N-terminal kinase and modulates cell growth."
      Haridas V. , Shrivastava A. , Su J. , Yu G.-L. , Ni J. , Liu D. , Chen S.-F. , Ni Y. , Ruben S.M. , Gentz R. , Aggarwal B.B.
      Oncogene18:6496-6504(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    10. 10.
      "X-ray crystal structure of TNF ligand family member TL1A at 2.1A."
      Jin T. , Guo F. , Kim S. , Howard A. , Zhang Y.-Z.
      Biochem. Biophys. Res. Commun.364:1-6(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 71-251;DISULFIDE BOND;SUBUNIT
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.45 ANGSTROMS) OF 72-251 IN COMPLEX WITH TNFRSF6B
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