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Index > Protein center > FASLG(Gene name) > Pig
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  • FASLG (Gene name),
  • Tumor necrosis factor ligand superfamily member 6 (Protein name ),  TNFL6_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FASLG(CD95L;FASL;TNFSF6);
    Protein name:
    Tumor necrosis factor ligand superfamily member 6;
    Alternative:
    Fas antigen ligand(Fas ligand);CD95 ligand(CD95-L);
    CD:
    CD178;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Homotrimer (Probable). Interacts with ARHGAP9, BAIAP2L1, BTK, CACNB3, CACNB4, CRK, DLG2, DNMBP, DOCK4, EPS8L3, FGR, FYB, FYN, HCK, ITK, ITSN2, KALRN, LYN, MACC1, MIA, MPP4, MYO15A, NCF1, NCK1, NCK2, NCKIPSD, OSTF1, PIK3R1, PSTPIP1, RIMBP3C, SAMSN1, SH3GL3, SH3PXD2B, SH3PXD2A, SH3RF2, SKAP2, SNX33, SNX9, SORBS3, SPTA1, SRC, SRGAP1, SRGAP2, SRGAP3, TEC, TJP3 and YES1.
    Function:
    Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
    Subcellular Location:
    Tumor necrosis factor ligand superfamily member 6, soluble form Secreted May be released into the extracellular fluid, probably by cleavage form the cell surface.
    Protein Attributes:
    Sequence length:
    282
    Sequence:
    50:
    MQQPFNYPYP | QIFWVDSSAT | SPWASPGSVF | PCPASVPGRP | GQRRPPPPPP | 
    100:
    PPPPPPTLLP | SRPLPPLPPP | SLKKKRDHNA | GLCLLVMFFM | VLVALVGLGL | 
    150:
    GMFQLFHLQK | ELTELRESAS | QRHTESSLEK | QIGHPNLPSE | KKELRKVAHL | 
    200:
    TGKPNSRSIP | LEWEDTYGIA | LVSGVKYMKG | SLVINDTGLY | FVYSKVYFRG | 
    250:
    QYCNNQPLSH | KVYTRNSRYP | QDLVLMEGKM | MNYCTTGQMW | ARSSYLGAVF | 
    282:
    NLTSADHLYV | NVSELSLVNF | EESKTFFGLY | KL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    E0031m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
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    ELISA Kit for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    E0031r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    E0031h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    E0031p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    U0031p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    U0031h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    U0031m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    U0031r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    P0031Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    P0031Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Tumor necrosis factor ligand superfamily member 6
    Cat.:
    P0031Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Tumor necrosis factor ligand superfamily member 6
    Monoclonal Antibody for Pig Tumor necrosis factor ligand superfamily member 6
    Monoclonal Antibody for Pig Tumor necrosis factor ligand superfamily member 6
    Monoclonal Antibody for Pig Tumor necrosis factor ligand superfamily member 6
    Monoclonal Antibody for Pig Tumor necrosis factor ligand superfamily member 6
    Protein for Pig Tumor necrosis factor ligand superfamily member 6
    Protein for Pig Tumor necrosis factor ligand superfamily member 6
    Protein for Pig Tumor necrosis factor ligand superfamily member 6
    Protein for Pig Tumor necrosis factor ligand superfamily member 6

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    Linearity
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    References
    1. 1.
      "Molecular cloning, characterization, and expression of porcine Fas ligand (CD95 ligand)."
      Muneta Y. , Shimoji Y. , Inumaru S. , Mori Y.
      J. Interferon Cytokine Res.21:305-312(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Porcine Fas-ligand gene: genomic sequence analysis and comparison with human gene."
      Motegi-Ishiyama Y. , Nakajima Y. , Hoka S. , Takagaki Y.
      Mol. Immunol.38:581-586(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: Landrace X Large Yorkshire white.
      tissue: Thymocyte.
    3. 3.
      "Cloning and potential utility of porcine Fas ligand: overexpression in porcine endothelial cells protects them from attack by human cytolytic cells."
      Tsuyuki S. , Kono M. , Bloom E.T.
      Xenotransplantation9:410-421(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lymphoid tissue.
    4. 4.
      "Molecular cloning and characterization of porcine Fas ligand cDNA."
      Zhu N. , Young Y.
      Submitted (2001-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Guanxi bama miniature pig.
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