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Index > Protein center > Ngfr(Gene name) > Mouse
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  • Ngfr (Gene name),
  • Tumor necrosis factor receptor superfamily member 16 (Protein name ),  TNR16_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Ngfr(Tnfrsf16);
    Protein name:
    Tumor necrosis factor receptor superfamily member 16;
    Alternative:
    Low-affinity nerve growth factor receptor(NGF receptor);Low affinity neurotrophin receptor p75NTR;
    CD:
    CD271;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts with BEX1. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with NGFRAP1/BEX3. Interacts with KIDINS220 and NTRK1. Can form a ternary complex with NTRK1 and KIDINS220 and this complex is affected by the expression levels of KIDINS220. An increase in KIDINS220 expression leads to a decreased association of NGFR and NTRK1 (By similarity). Interacts with LINGO1.
    Function:
    Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells (By similarity). Binds to rabies virus glycoprotein Gs.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    417
    Sequence:
    50:
    MDRLRLLLLL | LLLLGVSFGG | AKETCSTGMY | THSGECCKAC | NLGEGVAQPC | 
    100:
    GANQTVCEPC | LDSVTFSDVV | SATEPCKPCT | ECLGLQSMSA | PCVEADDAVC | 
    150:
    RCSYGYYQDE | ETGRCEACSV | CGVGSGLVFS | CQDKQNTVCE | ECPEGTYSDE | 
    200:
    ANHVDPCLPC | TVCEDTERQL | RECTPWADAE | CEEIPGRWIT | RSTPPEGSDV | 
    250:
    TTPSTQEPEA | PPERDLIAST | VADTVTTVMG | SSQPVVTRGT | ADNLIPVYCS | 
    300:
    ILAAVVVGLV | AYIAFKRWNS | CKQNKQGANS | RPVNQTPPPE | GEKLHSDSGI | 
    350:
    SVDSQSLHDQ | QTHTQTASAQ | ALKGDGNLYS | SLPLTKREEV | EKLLNGDTWR | 
    400:
    HLAGELGYQP | EHIDSFTHEA | CPVRALLASW | GAQDSATLDA | LLAALRRIQR | 
    417:
    ADIVESLCSE | STATSPV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    E9231r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    E9231c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    E9231m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    E9231h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    U9231r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    U9231m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    U9231h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    U9231c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    P9231Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    P9231Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 16
    Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 16
    Cat.:
    P9231Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 16
    Monoclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 16
    Monoclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 16
    Monoclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 16
    Protein for Mouse Tumor necrosis factor receptor superfamily member 16
    Protein for Mouse Tumor necrosis factor receptor superfamily member 16
    Protein for Mouse Tumor necrosis factor receptor superfamily member 16
    Protein for Mouse Tumor necrosis factor receptor superfamily member 16

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    References
    1. 1.
      "Low-affinity nerve-growth factor receptor (p75NTR) can serve as a receptor for rabies virus."
      Tuffereau C. , Benejean J. , Blondel D. , Kieffer B. , Flamand A.
      EMBO J.17:7250-7259(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: A.
    2. 2.
      "Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis."
      Mukai J. , Shoji S. , Kimura M.T. , Okubo S. , Sano H. , Suvanto P. , Li Y. , Irie S. , Sato T.-A.
      J. Biol. Chem.277:13973-13982(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NGFRAP1
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH RAB31
    4. 4.
      "p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks."
      Baeza-Raja B. , Eckel-Mahan K. , Zhang L. , Vagena E. , Tsigelny I.F. , Sassone-Corsi P. , Ptacek L.J. , Akassoglou K.
      J. Neurosci.33:10221-10234(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
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