TNFRSF17 ELISA Kit for Human(Homo sapiens) | EIAab.comTNFRSF17 ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > TNFRSF17(Gene name) > Human

TNFRSF17 (Gene name),

Tumor necrosis factor receptor superfamily member 17 (Protein name ), TNR17_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

TNFRSF17(BCM;BCMA);

Protein name:

Tumor necrosis factor receptor superfamily member 17;

Alternative:

B-cell maturation protein;

CD:

CD269;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.

Function:

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.

Subcellular Location:

Cell membrane Single-pass type III membrane protein Endomembrane system Single-pass type III membrane protein Perinuclear Golgi-like structures.

Protein Attributes:

Sequence length:

184

Sequence:

50:

100:

150:

184:

EGATILVTTK | TNDYCKSLPA | ALSATEIEKS | ISAR

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

Q02223

STRING:

9606.ENSP00000053243

UniGene:

Hs.2556

String:

Q02223

MIM:

109545

Pfam:

PF09257

KEGG:

hsa:608

Uniprot:

Q02223

FOR

ELISA Kit for Human Tumor necrosis factor receptor superfamily member 17

Cat.:

E8947m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human Tumor necrosis factor receptor superfamily member 17

Cat.:

E8947h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Tumor necrosis factor receptor superfamily member 17

Cat.:

U8947m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Tumor necrosis factor receptor superfamily member 17

Cat.:

U8947h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 17

Cat.:

P8947Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 17

Cat.:

P8947Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 17

Protein for Human Tumor necrosis factor receptor superfamily member 17

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma."
Laabi Y. , Gras M.P. , Carbonnel F. , Brouet J.C. , Berger R. , Larsen C.-J. , Tsapis A.
EMBO J.11:3897-3904(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);CHROMOSOMAL TRANSLOCATION;VARIANT SER-81
tissue: Lymph node.
tissue: Peripheral blood leukocyte.
2.

"The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed."
Laabi Y. , Gras M.P. , Brouet J.C. , Berger R. , Larsen C.J. , Tsapis A.
Nucleic Acids Res.22:1147-1154(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1);VARIANT SER-81
3.

"Presence of four major haplotypes in human BCMA gene: lack of association with systemic lupus erythematosus and rheumatoid arthritis."
Kawasaki A. , Tsuchiya N. , Fukazawa T. , Hashimoto H. , Tokunaga K.
Genes Immun.2:276-279(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-81 AND THR-153
4.

"Identification of new splice variants of the genes BAFF and BCMA."
Smirnova A.S. , Andrade-Oliveira V. , Gerbase-DeLima M.
Mol. Immunol.45:1179-1183(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Peripheral blood.
5.

"Novel, secreted isoform of human tumor necrosis factor receptor superfamily, member 17 (TNFRSF17)."
Maia S. , Freeman G.J. , Nadler L.M. , Cardoso A.A.
Submitted (2004-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
6.

NIEHS SNPs program
Submitted (2003-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS VAL-54; VAL-65; VAL-75; SER-81 AND SER-165
7.

"Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."
Loftus B.J. , Kim U.-J. , Sneddon V.P. , Kalush F. , Brandon R. , Fuhrmann J. , Mason T. , Crosby M.L. , Barnstead M. , Cronin L. , Mays A.D. , Cao Y. , Xu R.X. , Kang H.-L. , Mitchell S. , Eichler E.E. , Harris P.C. , Venter J.C. , more...
Genomics60:295-308(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT SER-81
8.

"The sequence and analysis of duplication-rich human chromosome 16."
Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase."
Hatzoglou A. , Roussel J. , Bourgeade M.-F. , Rogier E. , Madry C. , Inoue J. , Devergne O. , Tsapis A.
J. Immunol.165:1322-1330(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TRAF1 AND TRAF3
10.

"TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease."
Gross J.A. , Johnston J. , Mudri S. , Enselman R. , Dillon S.R. , Madden K. , Xu W. , Parrish-Novak J. , Foster D. , Lofton-Day C. , Moore M. , Littau A. , Grossman A. , Haugen H. , Foley K. , Blumberg H. , Harrison K. , Kindsvogel W. , more...
Nature404:995-999(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
11.

"APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity."
Yu G. , Boone T. , Delaney J. , Hawkins N. , Kelley M.J. , Ramakrishnan M. , McCabe S. , Qiu W.R. , Kornuc M. , Xia X.-Z. , Guo J. , Stolina M. , Boyle W.J. , Sarosi I. , Hsu H. , Senaldi G. , Theill L.E.
Nat. Immunol.1:252-256(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH APRIL AND BAFF
12.

"B cell maturation protein is a receptor for the tumor necrosis factor family member TALL-1."
Shu H.-B. , Johnson H.
Proc. Natl. Acad. Sci. U.S.A.97:9156-9161(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF5 AND TRAF6
13.

"Ligand-receptor binding revealed by the TNF family member TALL-1."
Liu Y. , Hong X. , Kappler J. , Jiang L. , Zhang R. , Xu L. , Pan C.-H. , Martin W.E. , Murphy R.C. , Shu H.-B. , Dai S. , Zhang G.
Nature423:49-56(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 8-46 IN COMPLEX WITH TNFSF13B;DISULFIDE BONDS
14.

"Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding."
Hymowitz S.G. , Patel D.R. , Wallweber H.J. , Runyon S. , Yan M. , Yin J. , Shriver S.K. , Gordon N.C. , Pan B. , Skelton N.J. , Kelley R.F. , Starovasnik M.A.
J. Biol. Chem.280:7218-7227(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 5-51 IN COMPLEX WITH MOUSE TNFSF13B;DISULFIDE BONDS

Product Feedback Wall

* Email:
*Comments: