Tnfrsf1a ELISA Kit for Mouse(Mus musculus) | EIAab.comTnfrsf1a ELISA Kit for Mouse(Mus musculus)

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Tnfrsf1a (Gene name),

Tumor necrosis factor receptor superfamily member 1A (Protein name ), TNR1A_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Tnfrsf1a(Tnfr-1;Tnfr1);

Protein name:

Tumor necrosis factor receptor superfamily member 1A;

Alternative:

Tumor necrosis factor receptor type I(TNF-RI;TNFR-I);Tumor necrosis factor receptor 1(TNF-R1);p60;p55;

CD:

CD120a;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binding of TNF to the extracellular domain leads to homotrimerization. The aggregated death domains provide a novel molecular interface that interacts specifically with the death domain of TRADD. Various TRADD-interacting proteins such as TRAFS, RIPK1 and possibly FADD, are recruited to the complex by their association with TRADD. This complex activates at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. Interacts with BAG4, BRE, FEM1B, GRB2, SQSTM1 and TRPC4AP. Interacts with DAB2IP.

Function:

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

454

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

454:

RLPR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:21937

String:

P25118

Pfam:

PF00531

UniGene:

Mm.1258

SMR:

P25118

Uniprot:

P25118

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ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

E0131h

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96T

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ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

E0131m

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96T

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ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

E0131r

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ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

E0131b

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96T

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ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

E0131p

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96T

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CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

U0131p

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96T

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CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

U0131b

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96T

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CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

U0131h

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Looking for manual.

MSDS:

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96T

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CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

U0131m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

U0131r

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96T

Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

P0131Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

P0131Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 1A

Cat.:

P0131Rb-h

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Packing:

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Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 1A

Monoclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 1A

Protein for Mouse Tumor necrosis factor receptor superfamily member 1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific."
Lewis M. , Tartaglia L.A. , Lee A. , Bennett G.L. , Rice G.C. , Wong G.H. , Chen E.Y. , Goeddel D.V.
Proc. Natl. Acad. Sci. U.S.A.88:2830-2834(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor."
Goodwin R.G. , Anderson D. , Jerzy R. , Davis T. , Brannan C.I. , Copeland N.G. , Jenkins N.A. , Smith C.A.
Mol. Cell. Biol.11:3020-3026(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Cloning, expression and cross-linking analysis of the murine p55 tumor necrosis factor receptor."
Barrett K. , Taylor-Fishwick D.A. , Cope A.P. , Kissonerghis A.M. , Gray P.W. , Feldmann M. , Foxwell B.M.J.
Eur. J. Immunol.21:1649-1656(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Molecular cloning and expression of the mouse Tnf receptor type b."
Rothe J.G. , Brockhaus M. , Gentz R. , Lesslauer W.
Immunogenetics34:338-340(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Spleen.
5.

"Nucleotide sequence of the TNF type I receptor from a mouse endothelioma cell line."
Bebo B.F. , Linthicum D.S.
Immunogenetics39:450-451(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
6.

"Genomic organization and promoter function of the murine tumor necrosis factor receptor beta gene."
Rothe J. , Bluethmann H. , Gentz R. , Lesslauer W. , Steinmetz M.
Mol. Immunol.30:165-175(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C3H/He.
tissue: Mesenchymal cell.

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