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Index > Protein center > TNFRSF4(Gene name) > Human
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  • TNFRSF4 (Gene name),
  • Tumor necrosis factor receptor superfamily member 4 (Protein name ),  TNR4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TNFRSF4(TXGP1L);
    Protein name:
    Tumor necrosis factor receptor superfamily member 4;
    Alternative:
    OX40L receptor;ACT35 antigen;CD134;TAX transcriptionally-activated glycoprotein 1 receptor;
    CD:
    CD134;
    Organism:
    TNFRSF4 (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with TRAF2, TRAF3 and TRAF5.
    Function:
    Receptor for TNFSF4/OX40L/GP34.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    277
    Sequence:
    50:
    MCVGARRLGR | GPCAALLLLG | LGLSTVTGLH | CVGDTYPSND | RCCHECRPGN | 
    100:
    GMVSRCSRSQ | NTVCRPCGPG | FYNDVVSSKP | CKPCTWCNLR | SGSERKQLCT | 
    150:
    ATQDTVCRCR | AGTQPLDSYK | PGVDCAPCPP | GHFSPGDNQA | CKPWTNCTLA | 
    200:
    GKHTLQPASN | SSDAICEDRD | PPATQPQETQ | GPPARPITVQ | PTEAWPRTSQ | 
    250:
    GPSTRPVEVP | GGRAVAAILG | LGLVLGLLGP | LAILLALYLL | RRDQRLPPDA | 
    277:
    HKPPGGGSFR | TPIQEEQADA | HSTLAKI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    MIM:
    KEGG:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 4
    Cat.:
    E2163h
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    96T
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    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 4
    Cat.:
    E2163r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 4
    Cat.:
    E2163m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 4
    Cat.:
    U2163r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 4
    Cat.:
    U2163m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 4
    Cat.:
    U2163h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
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    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 4
    Cat.:
    P2163Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 4
    Cat.:
    P2163Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 4
    Cat.:
    P2163Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 4
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 4
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 4
    Protein for Human Tumor necrosis factor receptor superfamily member 4
    Protein for Human Tumor necrosis factor receptor superfamily member 4
    Protein for Human Tumor necrosis factor receptor superfamily member 4

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    References
    1. 1.
      "The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen."
      Latza U. , Duerkop H. , Schnittger S. , Ringeling J. , Eitelbach F. , Hummel M. , Fonatsch C. , Stein H.
      Eur. J. Immunol.24:677-683(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Identification of OX40 ligand and preliminary characterization of its activities on OX40 receptor."
      Baum P.R. , Gayle R.B. III , Ramsdell F. , Srinivasan S. , Sorensen R.A. , Watson M.L. , Seldin M.F. , Clifford K.N. , Grabstein K. , Alderson M.R.
      Circ. Shock44:30-34(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
    3. 3.
      "The HTLV-I protein transcriptionally modulates OX40 antigen expression."
      Pankow R. , Duerkop H. , Latza U. , Krause H. , Kunzendorf U. , Pohl T. , Bulfone-Paus S.
      J. Immunol.165:263-270(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      NIEHS SNPs program
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT CYS-10
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    7. 7.
      "4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB."
      Arch R.H. , Thompson C.B.
      Mol. Cell. Biol.18:558-565(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF1; TRAF2 AND TRAF3
    8. 8.
      "Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2- and TRAF5-mediated NF-kappaB activation."
      Kawamata S. , Hori T. , Imura A. , Takaori-Kondo A. , Uchiyama T.
      J. Biol. Chem.273:5808-5814(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF2 AND TRAF5
    9. 9.
      "The crystal structure of the costimulatory OX40-OX40L complex."
      Compaan D.M. , Hymowitz S.G.
      Structure14:1321-1330(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 29-170 IN COMPLEX WITH TNFSF4;DISULFIDE BONDS
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT IMD16 CYS-65
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