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Index > Protein center > VDR(Gene name) > Bovine
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  • VDR (Gene name),
  • Vitamin D3 receptor (Protein name ),  VDR_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VDR(NR1I1);
    Protein name:
    Vitamin D3 receptor(VDR);
    Alternative:
    Nuclear receptor subfamily 1 group I member 1;1,25-dihydroxyvitamin D3 receptor;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer in the absence of bound vitamin D3. Heterodimer with RXRA after vitamin D3 binding. Interacts with SMAD3. Interacts with MED1, NCOA1, NCOA2, NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Interacts (in a ligand-dependent manner) with BAZ1B/WSTF.
    Function:
    Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    426
    Sequence:
    50:
    MEATAASTSL | PDPGDFDRNV | PRICGVCGDR | ATGFHFNAMT | CEGCKGFFRR | 
    100:
    SMKRKALFTC | PFNGDCRITK | DNRRHCQACR | LKRCIDIGMM | KEFILTDEEV | 
    150:
    QRKREMILKR | KEEEALKDSL | RPKLSEEQQR | IITTLLEAHH | KTYDDTYSDF | 
    200:
    SQFRPPVRNS | EDEGNRPLRS | ILTPSFSGNS | SSSCSDHCTS | SPDTMEPTSF | 
    250:
    SNQDLNEEDS | DDPSVTLDLS | QLSMLPHLAD | LVSYSIQKVI | GFAKMIPGFR | 
    300:
    DLTPEDQIVL | LKSSAIEVIM | LRSNQSFTLD | DDMSWTCGSP | DYKYQVSDVT | 
    350:
    RAGHSLELIE | PLIKFQVGLK | KLNLHEEEHV | LLMAICIVSP | DRPGVQDAAL | 
    400:
    VEAIQDRLSN | TLQTYIRCRH | PPPGSHLLYA | KMIQKLADLR | SLNEEHSKQY | 
    426:
    RCLSFQPESS | MKLTPLLFEV | FGNEIS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
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    ELISA Kit for Bovine VDR
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    ELISA Kit for Bovine VDR
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    E0475h
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    ELISA Kit for Bovine VDR
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    E0475m
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    ELISA Kit for Bovine VDR
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    E0475b
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    ELISA Kit for Bovine VDR
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    E0475p
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    ELISA Kit for Bovine VDR
    Cat.:
    E0475c
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    Packing:
    96T
    CLIA Kit for Bovine VDR
    Cat.:
    U0475c
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    96T
    CLIA Kit for Bovine VDR
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    U0475p
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    Packing:
    96T
    CLIA Kit for Bovine VDR
    Cat.:
    U0475h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine VDR
    Cat.:
    U0475b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine VDR
    Cat.:
    U0475r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine VDR
    Cat.:
    U0475m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Bovine VDR
    Polyclonal Antibody for Bovine VDR
    Cat.:
    P0475Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine VDR
    Polyclonal Antibody for Bovine VDR
    Polyclonal Antibody for Bovine VDR
    Cat.:
    P0475Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine VDR
    Cat.:
    P0475Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine VDR
    Monoclonal Antibody for Bovine VDR
    Monoclonal Antibody for Bovine VDR
    Monoclonal Antibody for Bovine VDR
    Monoclonal Antibody for Bovine VDR
    Monoclonal Antibody for Bovine VDR
    Protein for Bovine VDR
    Protein for Bovine VDR
    Protein for Bovine VDR
    Protein for Bovine VDR
    Protein for Bovine VDR
    Protein for Bovine VDR

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    References
    1. 1.
      "Nucleotide sequence of the bovine vitamin D3 receptor."
      Neibergs H.L. , Bosworth B.T. , Reinhardt T.A.
      J. Dairy Sci.79:1313-1315(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY NUCLEOTIDE SEQUENCE
    2. 2.
      "The genome sequence of taurine cattle: a window to ruminant biology and evolution."
      The bovine genome sequencing and analysis consortium
      Science324:522-528(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Hereford.
    3. 3.
      "Specific binding protein for 1,25-dihydroxyvitamin D3 in bovine mammary gland."
      Reinhardt T.A. , Conrad H.R.
      Arch. Biochem. Biophys.203:108-116(1980) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    4. 4.
      "Milk fever and dietary cation-anion balance effects on concentration of vitamin D receptor in tissue of periparturient dairy cows."
      Goff J.P. , Reinhardt T.A. , Horst R.L.
      J. Dairy Sci.78:2388-2394(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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