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Index > Protein center > Vdr(Gene name) > Mouse
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  • Vdr (Gene name),
  • Vitamin D3 receptor (Protein name ),  VDR_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Vdr(Nr1i1);
    Protein name:
    Vitamin D3 receptor(VDR);
    Alternative:
    1,25-dihydroxyvitamin D3 receptor;Nuclear receptor subfamily 1 group I member 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer in the absence of bound vitamin D3. Heterodimer with RXRA after vitamin D3 binding. Interacts with SMAD3. Interacts with MED1, NCOA1, NCOA2, NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Interacts (in a ligand-dependent manner) with BAZ1B/WSTF.
    Function:
    Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    422
    Sequence:
    50:
    MEAMAASTSL | PDPGDFDRNV | PRICGVCGDR | ATGFHFNAMT | CEGCKGFFRR | 
    100:
    SMKRKALFTC | PFNGDCRITK | DNRRHCQACR | LKRCVDIGMM | KEFILTDEEV | 
    150:
    QRKREMIMKR | KEEEALKDSL | RPKLSEEQQH | IIAILLDAHH | KTYDPTYADF | 
    200:
    RDFRPPIRAD | VSTGSYSPRP | TLSFSGDSSS | NSDLYTPSLD | MMEPASFSTM | 
    250:
    DLNEEGSDDP | SVTLDLSPLS | MLPHLADLVS | YSIQKVIGFA | KMIPGFRDLT | 
    300:
    SDDQIVLLKS | SAIEVIMLRS | NQSFTLDDMS | WDCGSQDYKY | DITDVSRAGH | 
    350:
    TLELIEPLIK | FQVGLKKLNL | HEEEHVLLMA | ICIVSPDRPG | VQDAKLVEAI | 
    400:
    QDRLSNTLQT | YIRCRHPPPG | SHQLYAKMIQ | KLADLRSLNE | EHSKQYRSLS | 
    422:
    FQPENSMKLT | PLVLEVFGNE | IS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    KEGG:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse VDR
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    ELISA Kit for Mouse VDR
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    ELISA Kit for Mouse VDR
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    ELISA Kit for Mouse VDR
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    ELISA Kit for Mouse VDR
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    ELISA Kit for Mouse VDR
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    E0475c
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    CLIA Kit for Mouse VDR
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    U0475c
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    CLIA Kit for Mouse VDR
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    96T
    CLIA Kit for Mouse VDR
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    U0475b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse VDR
    Cat.:
    U0475r
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    MSDS:
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    96T
    CLIA Kit for Mouse VDR
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    U0475m
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    CLIA Kit for Mouse VDR
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    Packing:
    96T
    Polyclonal Antibody for Mouse VDR
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    P0475Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse VDR
    Polyclonal Antibody for Mouse VDR
    Polyclonal Antibody for Mouse VDR
    Polyclonal Antibody for Mouse VDR
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    P0475Rb-r
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    Packing:
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    Polyclonal Antibody for Mouse VDR
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    P0475Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse VDR
    Monoclonal Antibody for Mouse VDR
    Monoclonal Antibody for Mouse VDR
    Monoclonal Antibody for Mouse VDR
    Monoclonal Antibody for Mouse VDR
    Monoclonal Antibody for Mouse VDR
    Protein for Mouse VDR
    Protein for Mouse VDR
    Protein for Mouse VDR
    Protein for Mouse VDR
    Protein for Mouse VDR
    Protein for Mouse VDR

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    References
    1. 1.
      "Cloning and sequencing of the gene encoding the mouse vitamin D receptor."
      Kamei Y. , Kawada T. , Fukuwatari T. , Ono T. , Kato S. , Sugimoto E.
      Gene152:281-282(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: NOD.
      tissue: Intestine.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary tumor.
    5. 5.
      "Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system."
      Tsujikawa H. , Kurotaki Y. , Fujimori T. , Fukuda K. , Nabeshima Y.
      Mol. Endocrinol.17:2393-2403(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
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