Flt1 ELISA Kit for Mouse(Mus musculus) | EIAab.comFlt1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Flt1(Gene name) > Mouse

Flt1 (Gene name),

Vascular endothelial growth factor receptor 1 (Protein name ), VGFR1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Flt1(Emrk2;Flt;Vegfr1);

Protein name:

Vascular endothelial growth factor receptor 1(VEGFR-1);

Alternative:

Fms-like tyrosine kinase 1(FLT-1);Embryonic receptor kinase 2;Tyrosine-protein kinase receptor FLT;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with GNB2L1/RACK1.

Function:

Receptor for VEGF and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

1333

Sequence:

50:

100:

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1150:

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1250:

1300:

1333:

RPVQDDESEL | GKESCCSPPP | DYNSVVLYSS | PPA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P35969

Pfam:

PF07679

UniGene:

Mm.389712

KEGG:

mmu:14254

SMR:

P35969

Uniprot:

P35969

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ELISA Kit for Mouse VEGFR-1

Cat.:

E0147m

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Packing:

96T

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ELISA Kit for Mouse VEGFR-1

Cat.:

E0147r

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96T

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ELISA Kit for Mouse VEGFR-1

Cat.:

E0147h

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ELISA Kit for Mouse VEGFR-1

Cat.:

E0147c

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96T

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CLIA Kit for Mouse VEGFR-1

Cat.:

U0147h

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96T

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CLIA Kit for Mouse VEGFR-1

Cat.:

U0147m

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Looking for manual.

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Packing:

96T

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CLIA Kit for Mouse VEGFR-1

Cat.:

U0147r

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96T

CLIA Kit for Mouse VEGFR-1

Cat.:

U0147c

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96T

Polyclonal Antibody for Mouse VEGFR-1

Cat.:

P0147Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse VEGFR-1

Cat.:

P0147Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse VEGFR-1

Cat.:

P0147Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse VEGFR-1

Protein for Mouse VEGFR-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of murine FLT and FLT4."
Finnerty H. , Kelleher K. , Morris G.E. , Bean K. , Merberg D.M. , Kriz R. , Morris J.C. , Sookdeo H. , Turner K.J. , Wood C.R.
Oncogene8:2293-2298(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
tissue: Neonatal brain.
tissue: Placenta.
2.

"Isolation of a gene encoding a novel receptor tyrosine kinase from differentiated embryonic stem cells."
Choi K. , Wall C. , Hanratty R. , Keller G.
Oncogene9:1261-1266(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
3.

"Genomic organization of the flt-1 gene encoding for vascular endothelial growth factor (VEGF) receptor-1 suggests an intimate evolutionary relationship between the 7-Ig and the 5-Ig tyrosine kinase receptors."
Kondo K. , Hiratsuka S. , Subbalakshmi E. , Matsushime H. , Shibuya M.
Gene208:297-305(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
tissue: Lung.
4.

Lubec G. , Kang S.U.
Submitted (2007-04) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 110-119 AND 185-191;IDENTIFICATION BY MASS SPECTROMETRY
strain: C57BL/6.
tissue: Brain.
5.

"Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium."
Fong G.H. , Rossant J. , Gertsenstein M. , Breitman M.L.
Nature376:66-70(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION IN BLOOD VESSEL DEVELOPMENT DURING EMBRYOGENESIS
6.

"Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice."
Hiratsuka S. , Minowa O. , Kuno J. , Noda T. , Shibuya M.
Proc. Natl. Acad. Sci. U.S.A.95:9349-9354(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION IN MACROPHAGE MIGRATION
7.

"Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis."
Hiratsuka S. , Maru Y. , Okada A. , Seiki M. , Noda T. , Shibuya M.
Cancer Res.61:1207-1213(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN ANGIOGENESIS
8.

"The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis."
Kearney J.B. , Kappas N.C. , Ellerstrom C. , DiPaola F.W. , Bautch V.L.
Blood103:4527-4535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
9.

"Vascular endothelial growth factor receptor-1 regulates postnatal angiogenesis through inhibition of the excessive activation of Akt."
Nishi J. , Minamino T. , Miyauchi H. , Nojima A. , Tateno K. , Okada S. , Orimo M. , Moriya J. , Fong G.H. , Sunagawa K. , Shibuya M. , Komuro I.
Circ. Res.103:261-268(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN ANGIOGENESIS
10.

"Vascular endothelial growth factor receptor-1 signaling promotes mobilization of macrophage lineage cells from bone marrow and stimulates solid tumor growth."
Muramatsu M. , Yamamoto S. , Osawa T. , Shibuya M.
Cancer Res.70:8211-8221(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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