Protein name:
von Willebrand factor (vWF) ;
Alternative:
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Multimeric. Interacts with F8.
Function:
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Subcellular Location:
Secreted
Secreted
extracellular space
extracellular matrix
Localized to storage granules.
Protein Attributes:
50:
MSPTRLVRVL | LALALILPGK | LCTKGTVGRS | SMARCSLFGG | DFINTFDESM |
100:
YSFAGDCSYL | LAGDCQEHSV | SLIGGFQNGK | RVSLSVYLGE | FFDIHLFVNG |
150:
TMLQGTQSIS | MPYASNGLYL | EAEAGYYKLS | SEAYGFVARI | DGNGNFQVLL |
200:
SDRYFNKTCG | LCGNFNIFAE | DDFRTQEGTL | TSDPYDFANS | WALSSGEQRC |
250:
KRVSPPSSPC | NVSSDEVQQV | LWEQCQLLKS | ASVFARCHPL | VDPEPFVALC |
300:
ERTLCTCVQG | MECPCAVLLE | YARACAQQGI | VLYGWTDHSV | CRPACPAGME |
350:
YKECVSPCTR | TCQSLHVKEV | CQEQCVDGCS | CPEGQLLDEG | HCVGSAECSC |
400:
VHAGQRYPPG | ASLLQDCHTC | ICRNSLWICS | NEECPGECLV | TGQSHFKSFD |
450:
NRYFTFSGVC | HYLLAQDCQD | HTFSVVIETV | QCADDLDAVC | TRSVTVRLPG |
500:
HHNSLVKLKH | GGGVSMDGQD | IQIPLLQGDL | RIQHTVMASV | RLSYGEDLQM |
550:
DWDGRGRLLV | TLSPAYAGKT | CGLCGNYNGN | RGDDFVTPAG | LAEPLVEDFG |
600:
NAWKLLGACE | NLQKQHRDPC | SLNPRQARFA | EEACALLTSS | KFEPCHRAVG |
650:
PQPYVQNCRY | DVCSCSDGRD | CLCSAVANYA | AACARRGVHI | AWREPGFCAL |
700:
SCPQGQVYLQ | CGTPCNMTCR | SLSYPEEDCN | EVCLEGCFCP | PGLYLDERGD |
750:
CVPKAQCPCY | YDGEIFQPED | IFSDHHTMCY | CEDGFMHCTT | SGGLGSLLPN |
800:
PVLSSPRSHR | SKRSLSCRPP | MVKLVCPADN | PRAEGLECAK | TCQNYDLQCM |
850:
STGCVSGCLC | PQGMVRHENR | CVALERCPCF | HQGQEYAPGE | TVKIDCNTCV |
900:
CRDRKWNCTD | HVCDATCSAI | GMAHYLTFDG | LKYLFPGECQ | YVLVQDYCGS |
950:
NPGTFRILVG | NEGCSYPSVK | CKKRVTILVE | GGEIELFDGE | VNVKKPMKDE |
1000:
THFEVVESGQ | YVILLLGKAL | SVVWDHRLSI | SVTLKRTYQE | QVCGLCGNFD |
1050:
GIQNNDFTSS | SLQIEEDPVD | FGNSWKVNPQ | CADTKKVPLD | SSPAVCHNNI |
1100:
MKQTMVDSSC | RILTSDIFQD | CNRLVDPEPF | LDICIYDTCS | CESIGDCTCF |
1150:
CDTIAAYAHV | CAQHGKVVAW | RTATFCPQNC | EERNLHENGY | ECEWRYNSCA |
1200:
PACPITCQHP | EPLACPVQCV | EGCHAHCPPG | KILDELLQTC | IDPEDCPVCE |
1250:
VAGRRLAPGK | KIILNPSDPE | HCQICHCDGV | NFTCQACREP | GSLVVPPTEG |
1300:
PIGSTTSYVE | DTPEPPLHDF | HCSRLLDLVF | LLDGSSKLSE | DEFEVLKVFV |
1350:
VGMMEHLHIS | QKRIRVAVVE | YHDGSHAYIE | LKDRKRPSEL | RRITSQVKYA |
1400:
GSEVASTSEV | LKYTLFQIFG | KIDRPEASRI | ALLLMASQEP | SRLARNLVRY |
1450:
VQGLKKKKVI | VIPVGIGPHA | SLKQIHLIEK | QAPENKAFVF | SGVDELEQRR |
1500:
DEIINYLCDL | APEAPAPTQH | PPMAQVTVGS | ELLGVSSPGP | KRNSMVLDVV |
1550:
FVLEGSDKIG | EANFNKSREF | MEEVIQRMDV | GQDRIHVTVL | QYSYMVTVEY |
1600:
TFSEAQSKGE | VLQQVRDIRY | RGGNRTNTGL | ALQYLSEHSF | SVSQGDREQV |
1650:
PNLVYMVTGN | PASDEIKRMP | GDIQVVPIGV | GPHANVQELE | KIGWPNAPIL |
1700:
IHDFEMLPRE | APDLVLQRCC | SGEGLQIPTL | SPTPDCSQPL | DVVLLLDGSS |
1750:
SIPASYFDEM | KSFTKAFISR | ANIGPRLTQV | SVLQYGSITT | IDVPWNVAYE |
1800:
KVHLLSLVDL | MQQEGGPSQI | GDALSFAVRY | VTSEVHGARP | GASKAVVILV |
1850:
TDVSVDSVDA | AAEAARSNRV | TVFPIGIGDR | YSEAQLSSLA | GPKAGSNMVR |
1900:
LQRIEDLPTV | ATLGNSFFHK | LCSGFDRVCV | DEDGNEKRPG | DVWTLPDQCH |
1950:
TVTCLPDGQT | LLKSHRVNCD | RGPRPSCPNG | QPPLRVEETC | GCRWTCPCVC |
2000:
MGSSTRHIVT | FDGQNFKLTG | SCSYVLFQNK | EQDLEVILHN | GACSPGAKET |
2050:
CMKSIEVKHD | GLSVELHSDM | QMTVNGRLVS | IPYVGGDMEV | NVYGTIMYEV |
2100:
RFNHLGHIFT | FTPQNNEFQL | QLSPRTFASK | TYGLCGICDE | NGANDFILRD |
2150:
GTVTTDWKAL | IQEWTVQQLG | KTCQPVPEEQ | CPVSSSSHCQ | VLLSELFAEC |
2200:
HKVLAPATFY | AMCQPDSCHP | KKVCEAIALY | AHLCRTKGVC | VDWRRANFCA |
2250:
MSCPPSLVYN | HCEHGCPRLC | EGNTSSCGDQ | PSEGCFCPPN | QVMLEGSCVP |
2300:
EEACTQCISE | DGVRHQFLET | WVPAHQPCQI | CTCLSGRKVN | CTLQPCPTAR |
2350:
APTCGPCEVA | RLRQNAEQCC | PEYECVCDLV | SCDLPPVPPC | EDGLQMTLTN |
2400:
PGECRPNFTC | ACRKDECRRE | SPPSCPPHRT | LALRKTQCCD | EYECACNCVN |
2450:
STVSCPLGYL | ASAVTNDCGC | TTTTCFPDKV | CVHRGTIYPV | GQFWEEACDV |
2500:
CTCTDLEDSV | MGLRVAQCSQ | KPCEDNCLSG | FTYVLHEGEC | CGRCLPSACE |
2550:
VVIGSPRGDA | QSHWKNVGSH | WASPDNPCLI | NECVRVKEEV | FVQQRNVSCP |
2600:
QLNVPTCPTG | FQLSCKTSEC | CPTCHCEPLE | ACLLNGTIIG | PGKSLMIDVC |
2650:
TTCRCTVQVG | VISGFKLECR | KTTCEACPLG | YKEEKNQGEC | CGRCLPIACT |
2700:
IQLRGGQIMT | LKRDETIQDG | CDSHFCKVNE | RGEYIWEKRV | TGCPPFDEHK |
2750:
CLAEGGKIMK | IPGTCCDTCE | EPECKDIIAK | LQRVKVGDCK | SEEEVDIHYC |
2800:
EGKCASKAVY | SIHMEDVQDQ | CSCCSPTQTE | PMQVPLRCTN | GSLIYHEILN |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Pig
Dog
Bovine
Polyclonal Antibody for Dog vWF
Polyclonal Antibody for Dog vWF
Polyclonal Antibody for Dog vWF
Polyclonal Antibody for Dog vWF
Polyclonal Antibody for Dog vWF
Polyclonal Antibody for Dog vWF
Monoclonal Antibody for Dog vWF
Monoclonal Antibody for Dog vWF
Monoclonal Antibody for Dog vWF
Monoclonal Antibody for Dog vWF
Monoclonal Antibody for Dog vWF
Monoclonal Antibody for Dog vWF
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];SUBUNIT;SUBCELLULAR LOCATION
tissue :
Heart .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION TO 55
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];DISEASE
strain :
Scottish terrier .
tissue :
Uterus .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1234-1669
tissue :
Blood .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW