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Index > Protein center > Slc30a8(Gene name) > Mouse
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  • Slc30a8 (Gene name),
  • Zinc transporter 8 (Protein name ),  ZNT8_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc30a8(Znt8);
    Protein name:
    Zinc transporter 8(ZnT-8);
    Alternative:
    Solute carrier family 30 member 8;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Cytoplasmic vesicle secretory vesicle membrane Multi-pass membrane protein Associated with the insulin and glucagon secretory granules.
    Protein Attributes:
    Sequence length:
    367
    Sequence:
    50:
    MEFLERTYLV | NDQATKMYAF | PLDRELRQKP | VNKDQCPGDR | PEHPEAGGIY | 
    100:
    HCHNSAKATG | NRSSKQAHAK | WRLCAASAIC | FIFMVAEVVG | GHVAGSLAIL | 
    150:
    TDAAHLLIDL | TSFLLSLFSL | WLSSRPPSKR | LTFGWYRAEI | LGALLSVLCI | 
    200:
    WVVTGVLLYL | ACERLLYPDY | QIQAGIMITV | SGCAVAANIV | LTMILHQRNF | 
    250:
    GYNHKDVQAN | ASVRAAFVHA | LGDVFQSISV | LISALIIYFK | PDYKIADPVC | 
    300:
    TFIFSILVLA | STVMILKDFS | ILLMEGVPKG | LSYNSVKEII | LAVDGVISVH | 
    350:
    SLHIWSLTVN | QVILSVHVAT | AASQDSQSVR | TGIAQALSSF | DLHSLTIQIE | 
    367:
    SAADQDPSCL | LCEDPQD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ZnT-8
    Cat.:
    E0319h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse ZnT-8
    Cat.:
    E0319r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse ZnT-8
    Cat.:
    E0319m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse ZnT-8
    Cat.:
    U0319m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ZnT-8
    Cat.:
    U0319h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse ZnT-8
    Cat.:
    U0319r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse ZnT-8
    Cat.:
    P0319Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ZnT-8
    Cat.:
    P0319Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ZnT-8
    Cat.:
    P0319Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse ZnT-8
    Monoclonal Antibody for Mouse ZnT-8
    Monoclonal Antibody for Mouse ZnT-8
    Protein for Mouse ZnT-8
    Protein for Mouse ZnT-8
    Protein for Mouse ZnT-8

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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Pancreas.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion."
      Chimienti F. , Devergnas S. , Pattou F. , Schuit F. , Garcia-Cuenca R. , Vandewalle B. , Kerr-Conte J. , Van Lommel L. , Grunwald D. , Favier A. , Seve M.
      J. Cell Sci.119:4199-4206(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    4. 4.
      "Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells."
      Gyulkhandanyan A.V. , Lu H. , Lee S.C. , Bhattacharjee A. , Wijesekara N. , Fox J.E. , MacDonald P.E. , Chimienti F. , Dai F.F. , Wheeler M.B.
      J. Biol. Chem.283:10184-10197(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands."
      Murgia C. , Devirgiliis C. , Mancini E. , Donadel G. , Zalewski P. , Perozzi G.
      Nutr. Metab. Cardiovasc. Dis.19:431-439(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HOMODIMERIZATION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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