Slc30a8 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comSlc30a8 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Slc30a8(Gene name) > Rat

Slc30a8 (Gene name),

Zinc transporter 8 (Protein name ), ZNT8_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Slc30a8(Znt8);

Protein name:

Zinc transporter 8(ZnT-8);

Alternative:

Solute carrier family 30 member 8;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer.

Function:

Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter (By similarity). May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells.

Subcellular Location:

Cell membrane Multi-pass membrane protein Cytoplasmic vesicle secretory vesicle membrane Multi-pass membrane protein Associated with insulin and glucagon secretory granules.

Protein Attributes:

Sequence length:

368

Sequence:

50:

100:

150:

200:

250:

300:

350:

368:

ESAADQDPSC | LLCEDPQD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:299903

Pfam:

PF01545

UniGene:

Rn.220601

Uniprot:

P0CE46

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ELISA Kit for Rat ZnT-8

Cat.:

E0319h

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96T

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ELISA Kit for Rat ZnT-8

Cat.:

E0319r

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96T

ELISA Kit for Rat ZnT-8

Cat.:

E0319m

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MSDS:

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Packing:

96T

CLIA Kit for Rat ZnT-8

Cat.:

U0319m

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MSDS:

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Packing:

96T

CLIA Kit for Rat ZnT-8

Cat.:

U0319h

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Manual:

Looking for manual.

MSDS:

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96T

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CLIA Kit for Rat ZnT-8

Cat.:

U0319r

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96T

Polyclonal Antibody for Rat ZnT-8

Cat.:

P0319Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat ZnT-8

Cat.:

P0319Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat ZnT-8

Cat.:

P0319Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat ZnT-8

Protein for Rat ZnT-8

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.

"Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands."
Murgia C. , Devirgiliis C. , Mancini E. , Donadel G. , Zalewski P. , Perozzi G.
Nutr. Metab. Cardiovasc. Dis.19:431-439(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
3.

"Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion."
Fu Y. , Tian W. , Pratt E.B. , Dirling L.B. , Shyng S.L. , Meshul C.K. , Cohen D.M.
PLoS ONE4:E5679-E5679(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
4.

"Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?"
Egefjord L. , Jensen J.L. , Bang-Berthelsen C.H. , Petersen A.B. , Smidt K. , Schmitz O. , Karlsen A.E. , Pociot F. , Chimienti F. , Rungby J. , Magnusson N.E.
BMC Endocr. Disord.9:7-7(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY IL1B AND IFNG

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