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Index > Protein center > TJP2(Gene name) > Dog
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  • TJP2 (Gene name),
  • Tight junction protein ZO-2 (Protein name ),  ZO2_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TJP2(ZO2);
    Protein name:
    Tight junction protein ZO-2;
    Alternative:
    Zona occludens protein 2;Tight junction protein 2;Zonula occludens protein 2;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Homodimer, and heterodimer with ZO1 and UBN1. Interacts with SCRIB (By similarity). Interacts with occludin and SAFB. Interaction with SAFB occurs in the nucleus.
    Function:
    Plays a role in tight junctions and adherens junctions.
    Subcellular Location:
    Cell membrane Peripheral membrane protein Cytoplasmic side Nucleus Cell junction tight junction Also nuclear under environmental stress conditions and in migratory endothelial cells and subconfluent epithelial cell cultures.
    Protein Attributes:
    Sequence length:
    1174
    Sequence:
    50:
    MEELIWEQYT | VTLQKDSKRG | FGIAVSGGRD | NPHFENGETS | IVISDVLPGG | 
    100:
    PADGLLQEND | RVVMVNGTPM | EDVLHSFAVQ | QLRKSGKIAA | IVVKRPRKVQ | 
    150:
    LAPPQGSLPV | DEDDRAFEVM | DEFDGRSARS | GYSERSRRSS | HGGRSRSWED | 
    200:
    SPERGRPHER | AWSQERERSR | GRSLERGLDH | DDDYRRPRER | SRGRSLERGL | 
    250:
    DHDDDYGRPG | ERSHGMSTDR | GYDRGYDRGY | DRGYDRTYSP | EAEYGRRTQP | 
    300:
    DARHAGSRSR | SREHLRSRSP | SPELRGRPDH | AGQPDSDRPI | GVLLMKSKAN | 
    350:
    EEYGLRLGSQ | IFIKQMTRTA | LATKDGNLHE | GDIILKINGT | VTENMSLTDA | 
    400:
    RKLIEKSRGK | LQLVVLRDSK | QTLINIPSLN | DSDSEIEDIS | EIESNRSFSP | 
    450:
    EERRQQYSDY | DYHSSNEKLK | ERPNSREDMQ | NRWSRMGATP | TPFKSMGDIA | 
    500:
    SVVGTENSKE | PRYQEEPPAP | QPKAAPRTFL | RPSPEDEAIY | GPNTKMVRFK | 
    550:
    KGDSVGLRLA | GGNDVGIFVA | GIQEGTSAEQ | EGLQEGDQIL | KVNTQDFRGL | 
    600:
    VREDAVLYLL | EIPKGEMVTI | LAQSRADVYR | DILACGRGDS | FFIRSHFECE | 
    650:
    KETPQSLAFS | RGEVFRVVDT | LYDGKLGHWL | AVRIGNELEK | GLIPNKSRAE | 
    700:
    QMASVQNAQR | DNAGDRADFW | RMRGQRSGMK | KNLRKSREDL | TAAVSVSTKF | 
    750:
    PAYERVLLRE | AGFKRPVVLF | GPIADIALEK | LANELPDLFQ | TAKTEPKDAG | 
    800:
    SEKSSGVVRL | NTVRQIIEQD | KHALLDVTPK | AVDLLNYTQW | FPIVIFFNPD | 
    850:
    SRQGVKTMRQ | RLNPTSNKSS | RKLYDQANKL | KKTCAHLFTA | TINLNSANDS | 
    900:
    WFGSLKDTIQ | HQQGEAVWVS | EGKMEGMDDD | PEDRMSYLTA | MGADYLSCDS | 
    950:
    RLISDFEDTD | GEGGAYTDNE | LDEPAEEPLV | SSITRSSEPV | QHEESIRKPS | 
    1000:
    PEPRAQMRRA | ASRDQLRDSS | PPPAFKPEPP | KAKTQNREES | FDISRSHDYK | 
    1050:
    SNPSAVAGNE | VSGASTRSCP | PPIAAKPSFG | RSILKPSTPV | PSPESEEVGE | 
    1100:
    GSEEQEGAPK | SVLGKVKIFE | KMDHKARLQR | MQELQEAQNA | RIEIAQKHPD | 
    1150:
    IYAVPIKTHK | PDPGLSQHTS | SRPPEPQKGP | SRLYQDPRGS | YGSDAEEEEY | 
    1174:
    RQQLSEHSKR | GYYSQPSRYR | DTEL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Dog Tight junction protein ZO-2
    ELISA Kit for Dog Tight junction protein ZO-2
    ELISA Kit for Dog Tight junction protein ZO-2
    CLIA Kit for Dog Tight junction protein ZO-2
    CLIA Kit for Dog Tight junction protein ZO-2
    CLIA Kit for Dog Tight junction protein ZO-2
    Polyclonal Antibody for Dog Tight junction protein ZO-2
    Polyclonal Antibody for Dog Tight junction protein ZO-2
    Polyclonal Antibody for Dog Tight junction protein ZO-2
    Monoclonal Antibody for Dog Tight junction protein ZO-2
    Monoclonal Antibody for Dog Tight junction protein ZO-2
    Monoclonal Antibody for Dog Tight junction protein ZO-2
    Protein for Dog Tight junction protein ZO-2
    Protein for Dog Tight junction protein ZO-2
    Protein for Dog Tight junction protein ZO-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The tight junction protein ZO-2 contains three PDZ (PSD-95/Discs-Large/ZO-1) domains and an alternatively spliced region."
      Beatch M. , Jesaitis L.A. , Gallin W. , Goodenough D.A. , Stevenson B.R.
      J. Biol. Chem.271:25723-25726(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Cocker spaniel.
      tissue: Kidney.
    2. 2.
      "Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein."
      Jesaitis L.A. , Goodenough D.A.
      J. Cell Biol.124:949-961(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA]
      strain: Cocker spaniel.
      tissue: Kidney.
    3. 3.
      "The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B."
      Traweger A. , Fuchs R. , Krizbai I.A. , Weiger T.M. , Bauer H.-C. , Bauer H.
      J. Biol. Chem.278:2692-2700(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH SAFB
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