Protein name:
Tight junction protein ZO-2 ;
Alternative:
Zona occludens protein 2 ;Tight junction protein 2 ;Zonula occludens protein 2 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer, and heterodimer with ZO1. Interacts with UBN1. Interacts with SCRIB (By similarity). Interacts with occludin and SAFB. Interaction with SAFB occurs in the nucleus.
Function:
Plays a role in tight junctions and adherens junctions.
Subcellular Location:
Cell membrane
Peripheral membrane protein
Cytoplasmic side
Nucleus
Cell junction
tight junction
Also nuclear under environmental stress conditions and in migratory endothelial cells and subconfluent epithelial cell cultures.
Protein Attributes:
50:
MEEVIWEQYT | VTLQKDSKRG | FGIAVSGGRD | NPHFENGETS | IVISDVLPGG |
100:
PADGLLQEND | RVVMVNGTPM | EDVLHSFAVQ | QLRKSGKIAA | IVVKRPRKVQ |
150:
VAPLQGSPPL | SHDDRGFEVI | EEFDGRSFRS | GYSERSRHSS | HDMLSHSWEG |
200:
NRERGRPHQR | TQSRERERSR | GRSLERGLDQ | EDYGRSRERS | RGRSLERGLD |
250:
RDFVSRDHSR | GRSIDRDYDR | DYERSYHEAY | EPDYGGGYSP | SYDRRAHPET |
300:
RYERSRSREH | LRSRSPSPES | RSRHEHKGQH | DPDRPIGVLL | TKSKANEEYG |
350:
LRLGSQIFIK | EMTRTGLATK | DGNLHEGDII | LKINGTVTEN | MSLTDARKLI |
400:
EKSRGKLQLV | VLRDSKQTLI | NIPALNDSDS | EVEDISEIES | NRSFSPEERR |
450:
QQYSDQDYHS | STEKLKERPS | SREETSGRLS | RMGATPTPFK | STGDITAAGV |
500:
TEASREPRYQ | EEGPVPQPRT | APRVFLRPSP | EDEAIYGPNT | KMVRFKKGDS |
550:
VGLRLAGGND | VGIFVAGIQE | GTSAEQEGLQ | EGDQILKVNT | QDFRGLVRED |
600:
AVLYLLEIPK | GETVTILAQS | RADVYRDILA | CGRGDSFFIR | SHFECEKETP |
650:
QSLAFTRGEV | FRVVDTLYDG | KLGHWLAVRI | GNELEKGLIP | NKSRAEQMAS |
700:
VQNAQRENAG | DRADFWRMRG | QRSSGGVKKN | LRKSREDLAA | AVSVSTKFPA |
750:
YEKVLLREAG | FKRPVVLFGP | IADIAMERLA | TELPDLFQTA | KTEPKDAGSE |
800:
KSSGVVRLNT | VRQIIEQDKH | ALLDVTPKAV | DLLNYTQWFP | IVIFFNPDSR |
850:
QGVKTIRQRL | SPTSNKSSRK | LFDQANKLKK | TCSHLFTATI | NVNSANDGWF |
900:
GSLKDSIQQQ | QNEAVWVSEG | KMEGMDDDAE | DRMSYLTAMG | ADYLSCDSRL |
950:
ISDFEDTDGE | GGAYTDNELE | EPAEEPLVSS | ITRSSEPVQH | EENIRKSSPE |
1000:
PRAQMRRAAS | RDQLRDASPP | PAFKPEPPKA | RSQNREDSFD | YSKSNLPATA |
1050:
GSEIPGGSTK | GYPPPIAAKP | AFGRPILKPS | TPVPMPESEE | VGESTEEQED |
1100:
APRSVLGRVK | IFEKMDHKAK | LQRMQELQEA | QNARIEIAQK | HPDIYAVPIK |
1150:
APKPDAGLPP | HMSSRPPEPQ | KAPSRLYQDT | RGSYGSDPEE | EEYRQQLAAH |
1167:
SKRGYYSQPS | RYRDTEL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Dog
Human
ELISA Kit for Mouse Tight junction protein ZO-2
ELISA Kit for Mouse Tight junction protein ZO-2
ELISA Kit for Mouse Tight junction protein ZO-2
CLIA Kit for Mouse Tight junction protein ZO-2
CLIA Kit for Mouse Tight junction protein ZO-2
CLIA Kit for Mouse Tight junction protein ZO-2
Polyclonal Antibody for Mouse Tight junction protein ZO-2
Polyclonal Antibody for Mouse Tight junction protein ZO-2
Polyclonal Antibody for Mouse Tight junction protein ZO-2
Monoclonal Antibody for Mouse Tight junction protein ZO-2
Monoclonal Antibody for Mouse Tight junction protein ZO-2
Monoclonal Antibody for Mouse Tight junction protein ZO-2
Protein for Mouse Tight junction protein ZO-2
Protein for Mouse Tight junction protein ZO-2
Protein for Mouse Tight junction protein ZO-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 X CBA .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
129 .
tissue :
Mammary gland .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;INTERACTION WITH SAFB
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-554;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-107;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1136;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-107;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-107;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-968 AND TYR-1095;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 1-106