FSHB(the gonadotropins follicle-stimulating hormone)is a 129-AA protein. FSH cells in response to the stimulus and gonadotropin-releasing hormone surge, indicate that gm increase fluorescence, and estrogen exposure leads to the decrease in the number of cells and transgenic fluorescence. growth factor receptor expression, and provide necessary evidence of FSH - dependent increase of epidermal growth factor receptor function.Our results indicate an unexpected role FSH in establishing signal axis coordinate events of ovulation and may lead to certain types of diagnosis and treatment of male infertility.
Expression and function of follicle-stimulating hormone receptor (FSHR) ovaries are thought to be limited for a long time. FSHR expression has the function of regulating pregnancy myometrium.The existence of FSHR have interaction with the placenta angiogenesis.
Analysis of transgenic mice in which FSHR is short of fetal portions of the placenta revealed adverse effects on fetoplacental development . Our data further proof FSHB and CGA mRNAs in the placenta and uterus, in accordance with potential local sources of FSH. Collectively, our data show that so far are not appreciate the role of the extragonadal FSHR female reproductive physiology.