Abstract

Extensive studies have demonstrated that oxidative stress plays a vital role in the pathology of
several  neurological  diseases,   including  autism  spectrum  disorder  (ASD);  those  studies
proposed  that  GSH  and  antioxidant  enzymes  have  a  pathophysiological  role  in  autism. 
Furthermore, Camel milk has emerged to have potential therapeutic effects in autism. The aim
of  the current study was to evaluate the effect of camel milk consumption on oxidative stress
biomarkers  in  autistic  children,  by  measuring  the  plasma  levels  of  glutathione,  superoxide
dismutase, and myeloperoxidase before and 2 weeks after camel milk consumption, using the
ELISA  technique.  All  measured  parameters  exhibited  significant  increase  after  camel  milk
consumption (p<0.5). These  findings suggest  that camel milk could play an  important role  in
decreasing  oxidative  stress  by  alteration  of  antioxidant  enzymes  and  non-enzymatic
antioxidant  molecules  levels,  as  well  as  the  improvement  of  autistic  behaviours  as
demonstrated by the improved Childhood Autism Rating Scales (CARS).