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Index > Protein center > CCL16(Gene name) > Human
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  • CCL16 (Gene name),
  • C-C motif chemokine 16 (Protein name ),  CCL16_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CCL16(ILINCK;NCC4;SCYA16);
    Protein name:
    C-C motif chemokine 16;
    Alternative:
    Chemokine LEC;Chemokine CC-4(HCC-4);LCC-1;IL-10-inducible chemokine;Lymphocyte and monocyte chemoattractant(LMC);Liver-expressed chemokine;NCC-4;Monotactin-1(MTN-1);Small-inducible cytokine A16;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    120
    Sequence:
    50:
    MKVSEAALSL | LVLILIITSA | SRSQPKVPEW | VNTPSTCCLK | YYEKVLPRRL | 
    100:
    VVGYRKALNC | HLPAIIFVTK | RNREVCTNPN | DDWVQEYIKD | PNLPLLPTRN | 
    120:
    LSTVKIITAK | NGQPQLLNSQ | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    SMR:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human C-C motif chemokine 16
    Cat.:
    E0138h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human C-C motif chemokine 16
    Cat.:
    U0138h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human C-C motif chemokine 16
    Cat.:
    P0138Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human C-C motif chemokine 16
    Protein for Human C-C motif chemokine 16

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    Precision
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    Linearity
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    References
    1. 1.
      "Characterization of a novel CC chemokine, HCC-4, whose expression is increased by interleukin-10."
      Hedrick J.A. , Helms A. , Vicari A. , Zlotnik A.
      Blood91:4242-4247(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF N-TERMINUS
      tissue: Liver.
    2. 2.
      "Isolation of cDNA encoding a novel human CC chemokine NCC-4/LEC."
      Shoudai K. , Hieshima K. , Fukuda S. , Iio M. , Miura R. , Imai T. , Yoshie O. , Nomiyama H.
      Biochim. Biophys. Acta1396:273-277(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    3. 3.
      "Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, LEC, and RANTES."
      Nomiyama H. , Fukuda S. , Iio M. , Tanase S. , Miura R. , Yoshie O.
      J. Interferon Cytokine Res.19:227-234(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Isolation and characterization of LMC, a novel lymphocyte and monocyte chemoattractant human CC chemokine, with myelosuppressive activity."
      Youn B.-S. , Zhang S. , Broxmeyer H.E. , Antol K. , Fraser M.J. Jr. , Hangoc G. , Kwon B.S.
      Biochem. Biophys. Res. Commun.247:217-222(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "Genomic organization of the genes for human and mouse CC chemokine LEC."
      Fukuda S. , Hanano Y. , Iio M. , Miura R. , Yoshie O. , Nomiyama H.
      DNA Cell Biol.18:275-283(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Liver.
    6. 6.
      "Cloning, characterization and genomic organization of LCC-1 (scya16), a novel human CC chemokine expressed in liver."
      Yang J.-Y. , Spanaus K.S. , Widmer U.
      Cytokine12:101-109(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      tissue: Liver.
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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