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Index > Protein center > Eme1(Gene name) > Mouse
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  • Eme1 (Gene name),
  • Crossover junction endonuclease EME1 (Protein name ),  EME1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Eme1;
    Protein name:
    Crossover junction endonuclease EME1;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    May self-associate (By similarity). Interacts with ERCC4 and FANCM (By similarity). Interacts with MUS81.
    Function:
    Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
    Subcellular Location:
    Nucleus nucleolus Recruited to regions of DNA damage in S-phase cells.
    Protein Attributes:
    Sequence length:
    570
    Sequence:
    50:
    MALRRLSLSR | LSTESDSEDL | PTFAFLKKEP | SSTNRKPPQR | AKNIVVVTSD | 
    100:
    SEASCPPSPG | LKGPPCVPSA | AGAPPQAGPV | RVLSSSSEDE | DVFVPLAERI | 
    150:
    TCKLLTSKQL | CPELSSSSLK | TGLDGQNNAS | APCDWKRQPW | PKIPDVPLHG | 
    200:
    ALEKSAANDE | DSLLDDQCRQ | LPTYQATCRE | LAVSKTNSDR | PLPKKRTKHI | 
    250:
    QTVQSGGSQG | CWRPGQASRK | ENTPRQHERK | KKAEMIKRLK | AQRPEECLKH | 
    300:
    IVVVLDPVLL | QMEGGGQLLG | ALQAMECSCV | IEVQAIPRSI | TWRRRRTELV | 
    350:
    EDGDDWMEEP | TILVLVLAEV | FMSMAYNLKQ | ASPSSTEKGK | ETLRSFVTDV | 
    400:
    TAKTGKALSL | VIVDQEKCFR | PQNPPRRRKS | GMANKQAKAK | HQQRQESSTG | 
    450:
    LMVSRADMEK | ALVDLQLYTE | AQAWMVQSWK | ELADFTCAFT | KAVAEAPFKK | 
    500:
    LRDQVTFSFF | LEKDWAGGMK | VDQSGRGLAL | IWRRQIQQLN | RVSSEMASAI | 
    550:
    VDAYPSPQLL | VQAYQRCFSE | QERQNLLADI | QVRRGEGVTA | TSRRVGPELS | 
    570:
    RRIYLQMTTA | QPDLILDSVD | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Crossover junction endonuclease EME1
    ELISA Kit for Mouse Crossover junction endonuclease EME1
    CLIA Kit for Mouse Crossover junction endonuclease EME1
    CLIA Kit for Mouse Crossover junction endonuclease EME1
    Polyclonal Antibody for Mouse Crossover junction endonuclease EME1
    Polyclonal Antibody for Mouse Crossover junction endonuclease EME1
    Monoclonal Antibody for Mouse Crossover junction endonuclease EME1
    Monoclonal Antibody for Mouse Crossover junction endonuclease EME1
    Protein for Mouse Crossover junction endonuclease EME1
    Protein for Mouse Crossover junction endonuclease EME1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Embryo.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      "Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells."
      Abraham J. , Lemmers B. , Hande M.P. , Moynahan M.E. , Chahwan C. , Ciccia A. , Essers J. , Hanada K. , Chahwan R. , Khaw A.K. , McPherson P. , Shehabeldin A. , Laister R. , Arrowsmith C. , Kanaar R. , West S.C. , Jasin M. , Hakem R.
      EMBO J.22:6137-6147(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH MUS81;TISSUE SPECIFICITY
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