Jdp2 ELISA Kit for Mouse(Mus musculus) | EIAab.comJdp2 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Jdp2(Gene name) > Mouse

Jdp2 (Gene name),

Jun dimerization protein 2 (Protein name ), JDP2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Jdp2(Jundm2);

Protein name:

Jun dimerization protein 2;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Forms homodimer or heterodimer with JUN, JUNB, JUND, CEBPG and ATF2 thereby inhibiting transactivation by JUN, ATF2 and CEBPG (By similarity). Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer.

Function:

Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1, such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

163

Sequence:

50:

100:

150:

163:

SEGNPLLEQL | DKK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00170

SMR:

P97875

String:

P97875

STRING:

10090.ENSMUSP00000059724

KEGG:

mmu:81703

UniGene:

Mm.103560

Uniprot:

P97875

FOR

ELISA Kit for Mouse Jun dimerization protein 2

CLIA Kit for Mouse Jun dimerization protein 2

Polyclonal Antibody for Mouse Jun dimerization protein 2

Monoclonal Antibody for Mouse Jun dimerization protein 2

Protein for Mouse Jun dimerization protein 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Jun dimerization protein 2 (JDP2), a member of the AP-1 family of transcription factor, mediates osteoclast differentiation induced by RANKL."
Kawaida R. , Ohtsuka T. , Okutsu J. , Takahashi T. , Kadono Y. , Oda H. , Hikita A. , Nakamura K. , Tanaka S. , Furukawa H.
J. Exp. Med.197:1029-1035(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Czech II.
tissue: Mammary tumor.
3.

"Identification of mouse Jun dimerization protein 2 as a novel repressor of ATF-2."
Jin C. , Ugai H. , Song J. , Murata T. , Nili F. , Sun K. , Horikoshi M. , Yokoyama K.K.
FEBS Lett.489:34-41(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INTERACTION WITH ATF2;DNA-BINDING
4.

"The AP-1 repressor, JDP2, is a bona fide substrate for the c-Jun N-terminal kinase."
Katz S. , Heinrich R. , Aronheim A.
FEBS Lett.506:196-200(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATF2;PHOSPHORYLATION AT THR-148 BY MAPK8;MUTAGENESIS OF THR-148
5.

"The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene."
Heinrich R. , Livne E. , Ben-Izhak O. , Aronheim A.
J. Biol. Chem.279:5708-5715(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in Escherichia coli by Jun N-terminal kinase 1."
Murata T. , Shinozuka Y. , Obata Y. , Yokoyama K.K.
Anal. Biochem.376:115-121(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATF2;PHOSPHORYLATION AT THR-148 BY MAPK8/JNK1;MUTAGENESIS OF THR-148

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