Protein name:
JNK1/MAPK8-associated membrane protein (JKAMP) ;
Alternative:
Medulloblastoma antigen MU-MB-50.4 homolog ;JNK1-associated membrane protein (JAMP) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with RNF5 and MAPK8, but not with MAPK9. Binding to MAPK8 occurs before and after exposure to stress, such as UV irradiation. After exposure to stress, interacts with phosphorylated MAPK8. Competes with DUSP10 for MAPK8 binding. Associates with multiple components of the proteasome and with ERAD regulatory proteins, including AMFR/GP78, CANX, PSMC1, PSMC2, PSMC3/TBP1, PSMC5, PSMC6, PSMD8, SEC61-ALPHA and UFD1L.
Function:
May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Protein Attributes:
50:
MAVDIQPACL | GLYCGKTLLF | KNGSSEIYGE | CGVCPRGQRT | NAQKYCQPCT |
100:
ESPELYDWLY | LGFMAMLPLV | LHWFFIEWYS | GKKSSSALFQ | HITALFECTM |
150:
AAIITLLVSD | PVGVLYIRSC | RVLMLSDWYT | MLYNPSPDYV | TTVHCTHEAV |
200:
YPLYTIVFVY | YAFCLVLMML | LRPLLVKKIA | CGLGKSDRFK | SIYAALYFFP |
250:
ILTVLQAVGG | GLLYYAFPYI | ILVLSLVTLA | VYMSASEIEN | CYDLLVRKKR |
300:
LIVLFSHWLL | HAYGIVSISR | VDRLEHDLPL | LALVPTPALF | YLFTAKFTEP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse JKAMP
ELISA Kit for Mouse JKAMP
Polyclonal Antibody for Mouse JKAMP
Polyclonal Antibody for Mouse JKAMP
Monoclonal Antibody for Mouse JKAMP
Monoclonal Antibody for Mouse JKAMP
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
"JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity."
Kadoya T.
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Khurana A.
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Tcherpakov M.
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Mol. Cell. Biol.25:8619-8630(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH RNF5 AND MAPK8;MUTAGENESIS OF SER-24;GLYCOSYLATION AT ASN-22
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"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain :
C57BL/6J .
tissue :
Hippocampus .
tissue :
Lung .
3.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
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Cheng Z.
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Eichler E.E.
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more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH AMFR; CANX; PSMC1; PSMC2; PSMC3; PSMC5; PSMC6; PSMC8; RNF5; SEC61-ALPHA AND UFD1L;SUBCELLULAR LOCATION;INDUCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH RNF5;UBIQUITINATION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
Czech II .