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Index > Protein center > Jkamp(Gene name) > Mouse
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  • Jkamp (Gene name),
  • JNK1/MAPK8-associated membrane protein (Protein name ),  JKAMP_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Jkamp(Jamp);
    Protein name:
    JNK1/MAPK8-associated membrane protein(JKAMP);
    Alternative:
    Medulloblastoma antigen MU-MB-50.4 homolog;JNK1-associated membrane protein(JAMP);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with RNF5 and MAPK8, but not with MAPK9. Binding to MAPK8 occurs before and after exposure to stress, such as UV irradiation. After exposure to stress, interacts with phosphorylated MAPK8. Competes with DUSP10 for MAPK8 binding. Associates with multiple components of the proteasome and with ERAD regulatory proteins, including AMFR/GP78, CANX, PSMC1, PSMC2, PSMC3/TBP1, PSMC5, PSMC6, PSMD8, SEC61-ALPHA and UFD1L.
    Function:
    May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    311
    Sequence:
    50:
    MAVDIQPACL | GLYCGKTLLF | KNGSSEIYGE | CGVCPRGQRT | NAQKYCQPCT | 
    100:
    ESPELYDWLY | LGFMAMLPLV | LHWFFIEWYS | GKKSSSALFQ | HITALFECTM | 
    150:
    AAIITLLVSD | PVGVLYIRSC | RVLMLSDWYT | MLYNPSPDYV | TTVHCTHEAV | 
    200:
    YPLYTIVFVY | YAFCLVLMML | LRPLLVKKIA | CGLGKSDRFK | SIYAALYFFP | 
    250:
    ILTVLQAVGG | GLLYYAFPYI | ILVLSLVTLA | VYMSASEIEN | CYDLLVRKKR | 
    300:
    LIVLFSHWLL | HAYGIVSISR | VDRLEHDLPL | LALVPTPALF | YLFTAKFTEP | 
    311:
    SRILSEGANG | H
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse JKAMP
    ELISA Kit for Mouse JKAMP
    CLIA Kit for Mouse JKAMP
    CLIA Kit for Mouse JKAMP
    Polyclonal Antibody for Mouse JKAMP
    Polyclonal Antibody for Mouse JKAMP
    Monoclonal Antibody for Mouse JKAMP
    Monoclonal Antibody for Mouse JKAMP
    Protein for Mouse JKAMP
    Protein for Mouse JKAMP

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity."
      Kadoya T. , Khurana A. , Tcherpakov M. , Bromberg K.D. , Didier C. , Broday L. , Asahara T. , Bhoumik A. , Ronai Z.
      Mol. Cell. Biol.25:8619-8630(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH RNF5 AND MAPK8;MUTAGENESIS OF SER-24;GLYCOSYLATION AT ASN-22
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Hippocampus.
      tissue: Lung.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AMFR; CANX; PSMC1; PSMC2; PSMC3; PSMC5; PSMC6; PSMC8; RNF5; SEC61-ALPHA AND UFD1L;SUBCELLULAR LOCATION;INDUCTION
    5. 5.
      "Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP)."
      Tcherpakov M. , Delaunay A. , Toth J. , Kadoya T. , Petroski M.D. , Ronai Z.A.
      J. Biol. Chem.284:12099-12109(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RNF5;UBIQUITINATION
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: Czech II.
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