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Index > Protein center > JPH4(Gene name) > Human
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  • JPH4 (Gene name),
  • Junctophilin-4 (Protein name ),  JPH4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    JPH4(JPHL1;KIAA1831);
    Protein name:
    Junctophilin-4(JP-4);
    Alternative:
    Junctophilin-like 1 protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory.
    Subcellular Location:
    Cell membrane Peripheral membrane protein Endoplasmic reticulum membrane Single-pass type IV membrane protein Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane.
    Protein Attributes:
    Sequence length:
    628
    Sequence:
    50:
    MSPGGKFDFD | DGGCYVGGWE | AGRAHGYGVC | TGPGAQGEYS | GCWAHGFESL | 
    100:
    GVFTGPGGHS | YQGHWQQGKR | EGLGVERKSR | WTYRGEWLGG | LKGRSGVWES | 
    150:
    VSGLRYAGLW | KDGFQDGYGT | ETYSDGGTYQ | GQWQAGKRHG | YGVRQSVPYH | 
    200:
    QAALLRSPRR | TSLDSGHSDP | PTPPPPLPLP | GDEGGSPASG | SRGGFVLAGP | 
    250:
    GDADGASSRK | RTPAAGGFFR | RSLLLSGLRA | GGRRSSLGSK | RGSLRSEVSS | 
    300:
    EVGSTGPPGS | EASGPPAAAP | PALIEGSATE | VYAGEWRADR | RSGFGVSQRS | 
    350:
    NGLRYEGEWL | GNRRHGYGRT | TRPDGSREEG | KYKRNRLVHG | GRVRSLLPLA | 
    400:
    LRRGKVKEKV | DRAVEGARRA | VSAARQRQEI | AAARAADALL | KAVAASSVAE | 
    450:
    KAVEAARMAK | LIAQDLQPML | EAPGRRPRQD | SEGSDTEPLD | EDSPGVYENG | 
    500:
    LTPSEGSPEL | PSSPASSRQP | WRPPACRSPL | PPGGDQGPFS | SPKAWPEEWG | 
    550:
    GAGAQAEELA | GYEAEDEAGM | QGPGPRDGSP | LLGGCSDSSG | SLREEEGEDE | 
    600:
    EPLPPLRAPA | GTEPEPIAML | VLRGSSSRGP | DAGCLTEELG | EPAATERPAQ | 
    628:
    PGAANPLVVG | AVALLDLSLA | FLFSQLLT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human JP-4
    ELISA Kit for Human JP-4
    ELISA Kit for Human JP-4
    CLIA Kit for Human JP-4
    CLIA Kit for Human JP-4
    CLIA Kit for Human JP-4
    Polyclonal Antibody for Human JP-4
    Polyclonal Antibody for Human JP-4
    Polyclonal Antibody for Human JP-4
    Monoclonal Antibody for Human JP-4
    Monoclonal Antibody for Human JP-4
    Monoclonal Antibody for Human JP-4
    Protein for Human JP-4
    Protein for Human JP-4
    Protein for Human JP-4

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Nakayama M. , Nakajima D. , Kikuno R. , Ohara O.
      DNA Res.8:85-95(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 334-628
      tissue: Brain.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 396-628
      tissue: Brain.
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