Protein name:
P-selectin ;
Alternative:
Granule membrane protein 140 (GMP-140) ;CD62 antigen-like family member P ;Platelet activation dependent granule-external membrane protein (PADGEM) ;Leukocyte-endothelial cell adhesion molecule 3 (LECAM3) ;
CD:
CD62P ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts with SNX17. Interacts with PSGL1/SEPL and PODXL2 and mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2, and specific tyrosine sulfation on PSGL1.
Function:
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MASCPKAIWN | WRFQRAVFRT | VQLLCFSVLI | FEVINQKEVS | AWTYHYSNKT |
100:
YSWNYSRAFC | QKYYTDLVAI | QNKNEIAYLN | ETIPYYNSYY | WIGIRKINNK |
150:
WTWVGTKKTL | TEEAENWADN | EPNNKRNNQD | CVEIYIKSLS | APGKWNDEPC |
200:
WKRKRALCYR | ASCQDMSCSK | QGECIETIGN | YTCSCYPGFY | GPECEYVREC |
250:
GEFDLPQHVH | MNCSHPLGNF | SFNSHCSFHC | AEGYALNGPS | ELECLASGIW |
300:
TNSPPQCVAV | QCPALKSPEQ | GSMSCVQSAE | AFQHQSSCSF | SCEEGFALVG |
350:
PEVVHCTALG | VWTAPTPVCK | ALQCQDLPTS | TKARVNCSHP | FGDFRYQSTC |
400:
SFTCDEGSFL | VGASVLQCLD | TGNWDAPFPE | CQAVTCAALP | NPQNGEKTCV |
450:
QPLGGSSYES | TCWFTCHEGF | SLSGPERLDC | TPSGHWTGSP | PTCEEVDTVS |
500:
APAPGVQCPT | LIAPKQGTMS | CQHHVRNFGL | NTTCHFGCKA | GFTLLGDSAL |
550:
QCRPSRQWTA | AAPTCRAVKC | AKLPVTEPIV | MNCSNPWGNF | SYGSTCSFHC |
600:
PEGQLLNGSE | RTVCQENGQW | STTMPTCQAG | PLTIQETLTY | VGGAAAGTTG |
646:
LVTGSILLAL | LRRRCRQKDD | GKSPLNPQSH | LGTYGVFTNA | AFDPSP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Bovine P-selectin
ELISA Kit for Bovine P-selectin
ELISA Kit for Bovine P-selectin
ELISA Kit for Bovine P-selectin
CLIA Kit for Bovine P-selectin
CLIA Kit for Bovine P-selectin
CLIA Kit for Bovine P-selectin
CLIA Kit for Bovine P-selectin
Polyclonal Antibody for Bovine P-selectin
Polyclonal Antibody for Bovine P-selectin
Polyclonal Antibody for Bovine P-selectin
Polyclonal Antibody for Bovine P-selectin
Monoclonal Antibody for Bovine P-selectin
Monoclonal Antibody for Bovine P-selectin
Monoclonal Antibody for Bovine P-selectin
Monoclonal Antibody for Bovine P-selectin
Protein for Bovine P-selectin
Protein for Bovine P-selectin
Protein for Bovine P-selectin
Protein for Bovine P-selectin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Capillary endothelium .