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Index > Protein center > MAP3K7(Gene name) > Bovine
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  • MAP3K7 (Gene name),
  • Mitogen-activated protein kinase kinase kinase 7 (Protein name ),  M3K7_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    MAP3K7;
    Protein name:
    Mitogen-activated protein kinase kinase kinase 7;
    Alternative:

    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Binds both upstream activators and downstream substrates in multimolecular complexes. Interacts with TAB1/MAP3K7IP1 and TAB2/MAP3K7IP2. Identified in the TRIKA2 complex composed of MAP3K7, TAB1/MAP3K7IP1 and TAB2/MAP3K7IP2. Interacts with PPM1L. Interaction with PP2A and PPP6C leads to its repressed activity. Interacts with TRAF6 and TAB1/MAP3K7IP1; during IL-1 signaling. Interacts with TAOK1 and TAOK2; interaction with TAOK2 interferes with MAP3K7 interaction with IKKA, thus preventing NF-kappa-B activation. Interacts with WDR34 (via WD domains). Interacts with RBCK1. Interacts with CYLD. Interacts with TGFBR1; induces MAP3K7 activation by TRAF6 (By similarity). Interacts with MAPK8IP1 and VRK2.
    Function:
    Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    579
    Sequence:
    50:
    MSTASAASSS | SSSSAGEMIE | APSQVLNFEE | IDYKEIEVEE | VVGRGAFGVV | 
    100:
    CKAKWRAKDV | AIKQIESESE | RKAFIVELRQ | LSRVNHPNIV | KLYGACLNPV | 
    150:
    CLVMEYAEGG | SLYNVLHGAE | PLPYYTAAHA | MSWCLQCSQG | VAYLHSMQPK | 
    200:
    ALIHRDLKPP | NLLLVAGGTV | LKICDFGTAC | DIQTHMTNNK | GSAAWMAPEV | 
    250:
    FEGSNYSEKC | DVFSWGIILW | EVITRRKPFD | EIGGPAFRIM | WAVHNGTRPP | 
    300:
    LIKNLPKPIE | SLMTRCWSKD | PSQRPSMEEI | VKIMTHLMRY | FPGADEPLQY | 
    350:
    PCQYSDEGQS | NSATSTGSFM | DITSTNTSNK | SDTNMEQVPA | TNDTIKRLES | 
    400:
    KLLKNQAKQQ | SESGRLSLGA | SRGSSVESLP | PTSEGKRMSA | DMSEIEARIA | 
    450:
    ATTGNGQPRR | RSIQDLTVTG | TDPGQVSSRS | SSPSVRMITT | SGPTSEKPAR | 
    500:
    SHPWTPDDST | DTNGSDNSIP | MAYLTLDHQL | QPLAPCPNSK | ESMAVFEQHC | 
    550:
    KMAQEYMKVQ | TEIALLLQRK | QELVAELDQD | EKDQQNTSRL | VQEHKKLLDE | 
    579:
    NKSLSTYYQQ | CKKQLEVIRS | QQQKRQGTS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Mitogen-activated protein kinase kinase kinase 7
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    E10349b
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    ELISA Kit for Bovine Mitogen-activated protein kinase kinase kinase 7
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    Packing:
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    CLIA Kit for Bovine Mitogen-activated protein kinase kinase kinase 7
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    U10349m
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    Packing:
    96T
    CLIA Kit for Bovine Mitogen-activated protein kinase kinase kinase 7
    Cat.:
    U10349r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Mitogen-activated protein kinase kinase kinase 7
    Cat.:
    U10349b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Mitogen-activated protein kinase kinase kinase 7
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    U10349h
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    Packing:
    96T
    Polyclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 7
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    P10349Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 7
    Polyclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 7
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    P10349Rb-r
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    Packing:
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    Polyclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 7
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    P10349Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 7
    Monoclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 7
    Monoclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 7
    Monoclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 7
    Protein for Bovine Mitogen-activated protein kinase kinase kinase 7
    Protein for Bovine Mitogen-activated protein kinase kinase kinase 7
    Protein for Bovine Mitogen-activated protein kinase kinase kinase 7
    Protein for Bovine Mitogen-activated protein kinase kinase kinase 7

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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Ascending colon.
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