Mapk3 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMapk3 ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Mapk3(Gene name) > Rat

Mapk3 (Gene name),

Mitogen-activated protein kinase 3 (Protein name ), MK03_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

Feedback

Gene name:

Mapk3(Erk1;Prkm3);

Protein name:

Mitogen-activated protein kinase 3(MAP kinase 3;MAPK 3);

Alternative:

Extracellular signal-regulated kinase 1(ERK-1);ERT2;MAP kinase isoform p44(p44-MAPK);Insulin-stimulated MAP2 kinase;Microtubule-associated protein 2 kinase;MNK1;p44-ERK1;Mitogen-activated protein kinase 1(MAP kinase 1;MAPK 1);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with NISCH, MORG1 and HSF4. Interacts with ARRB2 (By similarity). Interacts with ADAM15 (By similarity). Found in a complex with at least BRAF, HRAS1, MAP2K1, MAPK3 and RGS14.

Function:

Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4 (HSF4).

Subcellular Location:

Isoform 2 Nucleus

Protein Attributes:

Sequence length:

380

Sequence:

50:

100:

150:

200:

250:

300:

350:

380:

MELDDLPKER | LKELIFQETA | RFQPGAPEAP |

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Rn.2592

String:

P21708

SMR:

P21708

Pfam:

PF00069

KEGG:

rno:50689

Uniprot:

P21708

FOR

ELISA Kit for Rat MAP kinase 3

Cat.:

E1357h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat MAP kinase 3

Cat.:

E1357r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat MAP kinase 3

Cat.:

E1357m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Rat MAP kinase 3

Cat.:

U1357r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Rat MAP kinase 3

Cat.:

U1357h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Rat MAP kinase 3

Cat.:

U1357m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rat MAP kinase 3

Cat.:

P1357Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MAP kinase 3

Cat.:

P1357Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MAP kinase 3

Cat.:

P1357Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Rat MAP kinase 3

Protein for Rat MAP kinase 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"Cromolyn chitosan nanoparticles as a novel protective approach for colorectal cancer"

Tare K. M, Shohda A. E, Aliaa Nabil E, et al.

From:Chemico-Biological Interactions

References

1.

"Sequence of a rat cDNA encoding the ERK1-MAP kinase."
Marquardt B. , Stabel S.
Gene120:297-299(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain: Sprague-Dawley.
tissue: Brain.
2.

"ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK."
Yung Y. , Yao Z. , Hanoch T. , Seger R.
J. Biol. Chem.275:15799-15808(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
3.

Bienvenut W.V. , von Kriegsheim A.F. , Kolch W.
Submitted (2006-08) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-65; 96-132; 157-209; 213-221; 280-357 AND 361-380 (ISOFORM 2);CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;PHOSPHORYLATION AT THR-203 AND TYR-205;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Pheochromocytoma.
4.

Maisonpierre P.C. , le Beau M.M. , Espinosa R. III , Ip N.Y. , Belluscio L. , la Monte S.M. , Squinto S. , Furth M.E. , Yancopoulos G.D.
Submitted (1991-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 7-380 (ISOFORM 1)
5.

Lubec G. , Afjehi-Sadat L. , Kang S.U.
Submitted (2007-07) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 73-84 AND 183-190;IDENTIFICATION BY MASS SPECTROMETRY
strain: Sprague-Dawley.
tissue: Brain.
tissue: Spinal cord.
6.

"An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control."
Boulton T.G. , Yancopoulos G.D. , Gregory J.S. , Slaughter C. , Moomaw C. , Hsu J. , Cobb M.H.
Science249:64-67(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 14-380 (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
7.

"Molecular analysis of microtubule-associated protein-2 kinase cDNA from mouse and rat brain."
de Miguel C. , Kligman D. , Patel J. , Detera-Wadleigh S.D.
DNA Cell Biol.10:505-514(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 14-380 (ISOFORM 1)
tissue: Brain cortex.
8.

"Purification and properties of extracellular signal-regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase."
Boulton T.G. , Gregory J.S. , Cobb M.H.
Biochemistry30:278-286(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 43-64 AND 167-185;CHARACTERIZATION
9.

"Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation."
Seger R. , Ahn N.G. , Boulton T.G. , Yancopoulos G.D. , Panayotatos N. , Radziejewska E. , Ericsson L. , Bratlien R.L. , Cobb M.H. , Krebs E.G.
Proc. Natl. Acad. Sci. U.S.A.88:6142-6146(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: AUTOPHOSPHORYLATION
10.

"PHAS-I as a link between mitogen-activated protein kinase and translation initiation."
Lin T.-A. , Kong X. , Haystead T.A.J. , Pause A. , Belsham G.J. , Sonenberg N. , Lawrence J.C. Jr.
Science266:653-656(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF EIF4EBP1
11.

"Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
Hoffert J.D. , Pisitkun T. , Wang G. , Shen R.-F. , Knepper M.A.
Proc. Natl. Acad. Sci. U.S.A.103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-203 AND TYR-205;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.

"Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector."
Willard F.S. , Willard M.D. , Kimple A.J. , Soundararajan M. , Oestreich E.A. , Li X. , Sowa N.A. , Kimple R.J. , Doyle D.A. , Der C.J. , Zylka M.J. , Snider W.D. , Siderovski D.P.
PLoS ONE4:E4884-E4884(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH BRAF; HRAS; MAP2K1 AND RGS14
13.

"The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions."
Yoon S. , Seger R.
Growth Factors24:21-44(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
14.

"The ERK signaling cascade--views from different subcellular compartments."
Yao Z. , Seger R.
BioFactors35:407-416(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION;REVIEW ON SUBCELLULAR LOCATION
15.

"The ERK cascade: distinct functions within various subcellular organelles."
Wortzel I. , Seger R.
Genes Cancer2:195-209(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON ENZYME REGULATION;REVIEW ON FUNCTION

Product Feedback Wall

* Email:
*Comments: