Gene name:
MAP2K1 (MEK1;PRKMK1) ;
Protein name:
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1;MAPKK 1) ;
Alternative:
MAPK/ERK kinase 1 (MEK 1) ;ERK activator kinase 1 ;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
Interacts with MORG1. Interacts with ARRB2. Found in a complex with at least BRAF, HRAS1, MAP2K1, MAPK3 and RGS14 (By similarity). Interacts with VRK2.
Function:
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
Subcellular Location:
N/A
Protein Attributes:
50:
MPKKKPTPIQ | LNPAPDGSAV | NGTSSAETNL | EALQKKLEEL | ELDEQQRKRL |
100:
EAFLTQKQKV | GELKDDDFEK | ISELGAGNGG | VVFKVSHKPS | GLVMARKLIH |
150:
LEIKPAIRNQ | IIRELQVLHE | CNSPYIVGFY | GAFYSDGEIS | ICMEHMDGGS |
200:
LDQVLKKAGR | IPEQILGKVS | IAVIKGLTYL | REKHKIMHRD | VKPSNILVNS |
250:
RGEIKLCDFG | VSGQLIDSMA | NSFVGTRSYM | SPERLQGTHY | SVQSDIWSMG |
300:
LSLVEMAVGR | YPIPPPDAKE | LELMFGCQVE | GDAAETPPRP | RTPGRPLSSY |
350:
GMDSRPPMAI | FELLDYIVNE | PPPKLPSAVF | SLEFQDFVNK | CLIKNPAERA |
393:
DLKQLMVHAF | IKRSDAEEVD | FAGWLCSTIG | LNQPSTPTHA | AGV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Rabbit
ELISA Kit for Rabbit MAP kinase kinase 1
ELISA Kit for Rabbit MAP kinase kinase 1
ELISA Kit for Rabbit MAP kinase kinase 1
ELISA Kit for Rabbit MAP kinase kinase 1
CLIA Kit for Rabbit MAP kinase kinase 1
CLIA Kit for Rabbit MAP kinase kinase 1
CLIA Kit for Rabbit MAP kinase kinase 1
CLIA Kit for Rabbit MAP kinase kinase 1
Polyclonal Antibody for Rabbit MAP kinase kinase 1
Polyclonal Antibody for Rabbit MAP kinase kinase 1
Polyclonal Antibody for Rabbit MAP kinase kinase 1
Polyclonal Antibody for Rabbit MAP kinase kinase 1
Monoclonal Antibody for Rabbit MAP kinase kinase 1
Monoclonal Antibody for Rabbit MAP kinase kinase 1
Monoclonal Antibody for Rabbit MAP kinase kinase 1
Monoclonal Antibody for Rabbit MAP kinase kinase 1
Protein for Rabbit MAP kinase kinase 1
Protein for Rabbit MAP kinase kinase 1
Protein for Rabbit MAP kinase kinase 1
Protein for Rabbit MAP kinase kinase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PHOSPHORYLATION AT SER-218 AND SER-222 BY RAF
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 16-393;PARTIAL PROTEIN SEQUENCE
tissue :
Brain .
tissue :
Skeletal muscle .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-16; 85-96 AND 190-201
tissue :
Skeletal muscle .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 85-96 AND 190-201
tissue :
Skeletal muscle .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (3.46 ANGSTROMS) IN COMPLEX WITH ATP AND HUMAN KSR2;PHOSPHORYLATION