Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > NLRX1(Gene name) > Human
  • Add your favorite
  • NLRX1 (Gene name),
  • NLR family member X1 (Protein name ),  NLRX1_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    NLRX1(NOD26;NOD5;NOD9);
    Protein name:
    NLR family member X1;
    Alternative:
    Nucleotide-binding oligomerization domain protein 26;Caterpiller protein 11.3(CLR11.3);Nucleotide-binding oligomerization domain protein 9;Nucleotide-binding oligomerization domain protein 5;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with MAVS.
    Function:
    Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
    Subcellular Location:
    Mitochondrion outer membrane
    Protein Attributes:
    Sequence length:
    975
    Sequence:
    50:
    MRWGHHLPRA | SWGSGFRRAL | QRPDDRIPFL | IHWSWPLQGE | RPFGPPRAFI | 
    100:
    RHHGSSVDSA | PPPGRHGRLF | PSASATEAIQ | RHRRNLAEWF | SRLPREERQF | 
    150:
    GPTFALDTVH | VDPVIRESTP | DELLRPPAEL | ALEHQPPQAG | LPPLALSQLF | 
    200:
    NPDACGRRVQ | TVVLYGTVGT | GKSTLVRKMV | LDWCYGRLPA | FELLIPFSCE | 
    250:
    DLSSLGPAPA | SLCQLVAQRY | TPLKEVLPLM | AAAGSHLLFV | LHGLEHLNLD | 
    300:
    FRLAGTGLCS | DPEEPQEPAA | IIVNLLRKYM | LPQASILVTT | RPSAIGRIPS | 
    350:
    KYVGRYGEIC | GFSDTNLQKL | YFQLRLNQPY | CGYAVGGSGV | SATPAQRDHL | 
    400:
    VQMLSRNLEG | HHQIAAACFL | PSYCWLVCAT | LHFLHAPTPA | GQTLTSIYTS | 
    450:
    FLRLNFSGET | LDSTDPSNLS | LMAYAARTMG | KLAYEGVSSR | KTYFSEEDVC | 
    500:
    GCLEAGIRTE | EEFQLLHIFR | RDALRFFLAP | CVEPGRAGTF | VFTVPAMQEY | 
    550:
    LAALYIVLGL | RKTTLQKVGK | EVAELVGRVG | EDVSLVLGIM | AKLLPLRALP | 
    600:
    LLFNLIKVVP | RVFGRMVGKS | REAVAQAMVL | EMFREEDYYN | DDVLDQMGAS | 
    650:
    ILGVEGPRRH | PDEPPEDEVF | ELFPMFMGGL | LSAHNRAVLA | QLGCPIKNLD | 
    700:
    ALENAQAIKK | KLGKLGRQVL | PPSELLDHLF | FHYEFQNQRF | SAEVLSSLRQ | 
    750:
    LNLAGVRMTP | VKCTVVAAVL | GSGRHALDEV | NLASCQLDPA | GLRTLLPVFL | 
    800:
    RARKLGLQLN | SLGPEACKDL | RDLLLHDQCQ | ITTLRLSNNP | LTAAGVAVLM | 
    850:
    EGLAGNTSVT | HLSLLHTGLG | DEGLELLAAQ | LDRNRQLQEL | NVAYNGAGDT | 
    900:
    AALALARAAR | EHPSLELLHL | YFNELSSEGR | QVLRDLGGAA | EGGARVVVSL | 
    950:
    TEGTAVSEYW | SVILSEVQRN | LNSWDRARVQ | RHLELLLRDL | EDSRGATLNP | 
    975:
    WRKAQLLRVE | GEVRALLEQL | GSSGS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human NLR family member X1
    ELISA Kit for Human NLR family member X1
    ELISA Kit for Human NLR family member X1
    CLIA Kit for Human NLR family member X1
    CLIA Kit for Human NLR family member X1
    CLIA Kit for Human NLR family member X1
    Polyclonal Antibody for Human NLR family member X1
    Polyclonal Antibody for Human NLR family member X1
    Polyclonal Antibody for Human NLR family member X1
    Monoclonal Antibody for Human NLR family member X1
    Monoclonal Antibody for Human NLR family member X1
    Monoclonal Antibody for Human NLR family member X1
    Protein for Human NLR family member X1
    Protein for Human NLR family member X1
    Protein for Human NLR family member X1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "NODs: intracellular proteins involved in inflammation and apoptosis."
      Inohara N. , Nunez G.
      Nat. Rev. Immunol.3:371-382(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS SER-63 AND GLU-793
    2. 2.
      Kronos K.
      Submitted (2007-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Identification of a 500-kb region of common allelic loss in chromosome 11q23 in non-MYCN amplified type of neuroblastoma."
      Kubo T. , Arai Y. , Ohira M. , Gamou T. , Maeno G. , Sakiyama T. , Toyoda A. , Hattori M. , Sakaki Y. , Nakagawara A. , Ohki M.
      Submitted (2002-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS SER-63 AND GLU-793
      tissue: Colon.
      tissue: Placenta.
      tissue: Tongue.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 214-975 (ISOFORM 2);VARIANT GLU-793
      tissue: Bone.
      tissue: Brain.
    6. 6.
      "NOD-LRR proteins: role in host-microbial interactions and inflammatory disease."
      Inohara N. , Chamaillard M. , McDonald C. , Nunez G.
      Annu. Rev. Biochem.74:355-383(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    7. 7.
      "CATERPILLER: a novel gene family important in immunity, cell death, and diseases."
      Ting J.P.-Y. , Davis B.K.
      Annu. Rev. Immunol.23:387-414(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    8. 8.
      "NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production."
      Tattoli I. , Carneiro L.A. , Jehanno M. , Magalhaes J.G. , Shu Y. , Philpott D.J. , Arnoult D. , Girardin S.E.
      EMBO Rep.9:293-300(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH MAVS;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    10. 10.
      "Structure and functional characterization of the RNA-binding element of the NLRX1 innate immune modulator."
      Hong M. , Yoon S.I. , Wilson I.A.
      Immunity36:337-347(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.65 ANGSTROMS) OF 629-975;LRR REPEATS;SUBUNIT
    Product Feedback Wall
    Hot Genes
    Top Searches
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter