Pdk1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comPdk1 ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Pdk1(Gene name) > Rat

Pdk1 (Gene name),

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (Protein name ), PDK1_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Pdk1(Pdh);

Protein name:

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial;

Alternative:

Pyruvate dehydrogenase kinase isoform 1(PDH kinase 1);PDK p48;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

N/A

Function:

Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

Subcellular Location:

Mitochondrion matrix

Protein Attributes:

Sequence length:

434

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

434:

YNKAAWKHYR | TNHEADDWCV | PSREPKDMTT | FRSS

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

Pfam:

PF10436

SMR:

Q63065

String:

Q63065

UniGene:

Rn.11185

Uniprot:

Q63065

FOR

ELISA Kit for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Cat.:

E10511r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Cat.:

E10511h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Cat.:

E10511m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Cat.:

U10511h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Cat.:

U10511r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Cat.:

U10511m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Cat.:

P10511Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Monoclonal Antibody for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Protein for Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Primary structure of pyruvate dehydrogenase kinase establishes a new family of eukaryotic protein kinases."
Popov K.M. , Kedishvili N.Y. , Zhao Y. , Shimomura Y. , Crabb D.W. , Harris R.A.
J. Biol. Chem.268:26602-26606(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;FUNCTION;CATALYTIC ACTIVITY;ENZYME REGULATION;SUBUNIT;TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Heart.
2.

"Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex."
Bowker-Kinley M.M. , Davis W.I. , Wu P. , Harris R.A. , Popov K.M.
Biochem. J.329:191-196(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;ENZYME REGULATION;TISSUE SPECIFICITY
3.

"Selective modification of pyruvate dehydrogenase kinase isoform expression in rat pancreatic islets elicited by starvation and activation of peroxisome proliferator-activated receptor-alpha: implications for glucose-stimulated insulin secretion."
Sugden M.C. , Bulmer K. , Augustine D. , Holness M.J.
Diabetes50:2729-2736(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;TISSUE SPECIFICITY
4.

"Site specificity of four pyruvate dehydrogenase kinase isoenzymes toward the three phosphorylation sites of human pyruvate dehydrogenase."
Korotchkina L.G. , Patel M.S.
J. Biol. Chem.276:37223-37229(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;FUNCTION
5.

"Interaction between the individual isoenzymes of pyruvate dehydrogenase kinase and the inner lipoyl-bearing domain of transacetylase component of pyruvate dehydrogenase complex."
Tuganova A. , Boulatnikov I. , Popov K.M.
Biochem. J.366:129-136(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DLAT;ENZYME REGULATION;CATALYTIC ACTIVITY
6.

"Formation of functional heterodimers by isozymes 1 and 2 of pyruvate dehydrogenase kinase."
Boulatnikov I. , Popov K.M.
Biochim. Biophys. Acta1645:183-192(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;FUNCTION;INTERACTION WITH PDK2;SUBUNIT
7.

"Amyloid beta resistance in nerve cell lines is mediated by the Warburg effect."
Newington J.T. , Pitts A. , Chien A. , Arseneault R. , Schubert D. , Cumming R.C.
PLoS ONE6:E19191-E19191(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid beta and other toxins by decreasing mitochondrial respiration and reactive oxygen species production."
Newington J.T. , Rappon T. , Albers S. , Wong D.Y. , Rylett R.J. , Cumming R.C.
J. Biol. Chem.287:37245-37258(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes."
Abe Y. , Uchinami H. , Kudoh K. , Nakagawa Y. , Ise N. , Watanabe G. , Sato T. , Seki E. , Yamamoto Y.
Surgery152:869-878(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY HYPOXIA;FUNCTION

Product Feedback Wall

* Email:
*Comments: