Protein name:
Serum paraoxonase/arylesterase 1 (PON 1) ;
Alternative:
Serum aryldialkylphosphatase 1 ;Aromatic esterase 1 (A-esterase 1) ;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
Homodimer. Interacts with CLU.
Function:
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.
Subcellular Location:
Secreted
extracellular space
Protein Attributes:
50:
MAKLTALTLL | GLGLALFDGQ | KSSFQTRFNV | HREVTPVELP | NCNLVKGIDN |
100:
GSEDLEILPN | GLAFISAGLK | YPGIMSFDPD | KPGKILLMDL | NEKDPVVLEL |
150:
SITGSTFDLS | SFNPHGISTF | TDEDNIVYLM | VVNHPDSKST | VELFKFQEKE |
200:
KSLLHLKTIR | HKLLPSVNDI | VAVGPEHFYA | TNDHYFIDPY | LKSWEMHLGL |
250:
AWSFVTYYSP | NDVRVVAEGF | DFANGINISP | DGKYVYIAEL | LAHKIHVYEK |
300:
HANWTLTPLK | SLDFNTLVDN | ISVDPVTGDL | WVGCHPNGMR | IFYYDPKNPP |
350:
ASEVLRIQDI | LSKEPKVTVA | YAENGTVLQG | STVAAVYKGK | MLVGTVFHKA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
Rabbit
ELISA Kit for Rabbit PON 1
ELISA Kit for Rabbit PON 1
ELISA Kit for Rabbit PON 1
ELISA Kit for Rabbit PON 1
CLIA Kit for Rabbit PON 1
CLIA Kit for Rabbit PON 1
CLIA Kit for Rabbit PON 1
CLIA Kit for Rabbit PON 1
Polyclonal Antibody for Rabbit PON 1
Polyclonal Antibody for Rabbit PON 1
Polyclonal Antibody for Rabbit PON 1
Polyclonal Antibody for Rabbit PON 1
Monoclonal Antibody for Rabbit PON 1
Monoclonal Antibody for Rabbit PON 1
Monoclonal Antibody for Rabbit PON 1
Monoclonal Antibody for Rabbit PON 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
tissue :
Liver .
2.
"Human and rabbit paraoxonases: purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification."
Furlong C.E.
,
Costa L.G.
,
Hassett C.
,
Richter R.J.
,
Sundstrom J.A.
,
Adler D.A.
,
Disteche C.M.
,
Omiecinski C.J.
,
Chapline C.
,
Crabb J.W.
Chem. Biol. Interact.87:35-48(1993)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;VARIANTS SER-82; GLU-93 AND GLY-101
strain :
New Zealand white .
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-21;CATALYTIC ACTIVITY