ACAT1 ELISA Kit for Human(Homo sapiens) | EIAab.comACAT1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ACAT1(Gene name) > Human

ACAT1 (Gene name),

Acetyl-CoA acetyltransferase, mitochondrial (Protein name ), THIL_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ACAT1(ACAT;MAT);

Protein name:

Acetyl-CoA acetyltransferase, mitochondrial;

Alternative:

T2;Acetoacetyl-CoA thiolase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotetramer.

Function:

Plays a major role in ketone body metabolism.

Subcellular Location:

Mitochondrion

Protein Attributes:

Sequence length:

427

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

427:

ALKQGEYGLA | SICNGGGGAS | AMLIQKL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000265838

Pfam:

PF02803

UniGene:

Hs.232375

SMR:

P24752

String:

P24752

KEGG:

hsa:38

MIM:

203750

Uniprot:

P24752

FOR

ELISA Kit for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

E0247h

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Manual:

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Packing:

96T

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ELISA Kit for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

E0247m

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Packing:

96T

ELISA Kit for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

E0247r

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Packing:

96T

ELISA Kit for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

E0247b

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Packing:

96T

CLIA Kit for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

U0247r

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

U0247m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

U0247b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

U0247h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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Polyclonal Antibody for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

P0247Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

P0247Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Acetyl-CoA acetyltransferase, mitochondrial

Cat.:

P0247Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Acetyl-CoA acetyltransferase, mitochondrial

Protein for Human Acetyl-CoA acetyltransferase, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Molecular cloning and sequence of the complementary DNA encoding human mitochondrial acetoacetyl-coenzyme A thiolase and study of the variant enzymes in cultured fibroblasts from patients with 3-ketothiolase deficiency."
Fukao T. , Yamaguchi S. , Kano M. , Orii T. , Fujiki Y. , Osumi T. , Hashimoto T.
J. Clin. Invest.86:2086-2092(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"Structure and expression of the human mitochondrial acetoacetyl-CoA thiolase-encoding gene."
Kano M. , Fukao T. , Yamaguchi S. , Orii T. , Osumi T. , Hashimoto T.
Gene109:285-290(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
4.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT PRO-5
tissue: Brain.
7.

"Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."
Aboulaich N. , Vainonen J.P. , Stralfors P. , Vener A.V.
Biochem. J.383:237-248(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 50-78 AND 312-338
tissue: Adipocyte.
8.

Lubec G. , Chen W.-Q. , Sun Y.
Submitted (2008-12) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 50-78 AND 231-243;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Fetal brain cortex.
9.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-174; LYS-181; LYS-251 AND LYS-263;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.

"Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function."
Haapalainen A.M. , Merilaeinen G. , Pirilae P.L. , Kondo N. , Fukao T. , Wierenga R.K.
Biochemistry46:4305-4321(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 35-427 IN COMPLEX WITH COENZYME A AND POTASSIUM;SUBUNIT;BIOPHYSICOCHEMICAL PROPERTIES;CATALYTIC ACTIVITY;ENZYME REGULATION
12.

"Molecular basis of beta-ketothiolase deficiency: mutations and polymorphisms in the human mitochondrial acetoacetyl-coenzyme A thiolase gene."
Fukao T. , Yamaguchi S. , Orii T. , Hashimoto T.
Hum. Mutat.5:113-120(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON 3KTD VARIANTS
13.

"Identification of three mutant alleles of the gene for mitochondrial acetoacetyl-coenzyme A thiolase. A complete analysis of two generations of a family with 3-ketothiolase deficiency."
Fukao T. , Yamaguchi S. , Orii T. , Schutgens R.B.H. , Osumi T. , Hashimoto T.
J. Clin. Invest.89:474-479(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT 3KTD ARG-183
14.

"Evidence for a structural mutation (347Ala to Thr) in a German family with 3-ketothiolase deficiency."
Fukao T. , Yamaguchi S. , Tomatsu S. , Orii T. , Frauendienst-Egger G. , Schrod L. , Osumi T. , Hashimoto T.
Biochem. Biophys. Res. Commun.179:124-129(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT 3KTD THR-380
15.

"Molecular, biochemical, and clinical characterization of mitochondrial acetoacetyl-coenzyme A thiolase deficiency in two further patients."
Wakazono A. , Fukao T. , Yamaguchi S. , Hori T. , Orii T. , Lambert M. , Mitchell G.A. , Lee G.W. , Hashimoto T.
Hum. Mutat.5:34-42(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS 3KTD ASP-158; MET-297 AND PRO-301
16.

"Characterization of N93S, I312T, and A333P missense mutations in two Japanese families with mitochondrial acetoacetyl-CoA thiolase deficiency."
Fukao T. , Nakamura H. , Song X.-Q. , Nakamura K. , Orii K.E. , Kohno Y. , Kano M. , Yamaguchi S. , Hashimoto T. , Orii T. , Kondo N.
Hum. Mutat.12:245-254(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS 3KTD SER-93; THR-312 AND PRO-333

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