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Index > Protein center > EDA2R(Gene name) > Human
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  • EDA2R (Gene name),
  • Tumor necrosis factor receptor superfamily member 27 (Protein name ),  TNR27_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    EDA2R(UNQ2448/PRO5727/PRO34080;TNFRSF27;XEDAR);
    Protein name:
    Tumor necrosis factor receptor superfamily member 27;
    Alternative:
    X-linked ectodysplasin-A2 receptor(EDA-A2 receptor);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Associates with TRAF1, TRAF3 and TRAF6.
    Function:
    Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.
    Subcellular Location:
    Membrane Single-pass type III membrane protein
    Protein Attributes:
    Sequence length:
    297
    Sequence:
    50:
    MDCQENEYWD | QWGRCVTCQR | CGPGQELSKD | CGYGEGGDAY | CTACPPRRYK | 
    100:
    SSWGHHRCQS | CITCAVINRV | QKVNCTATSN | AVCGDCLPRF | YRKTRIGGLQ | 
    150:
    DQECIPCTKQ | TPTSEVQCAF | QLSLVEADTP | TVPPQEATLV | ALVSSLLVVF | 
    200:
    TLAFLGLFFL | YCKQFFNRHC | QRGGLLQFEA | DKTAKEESLF | PVPPSKETSA | 
    250:
    ESQVSENIFQ | TQPLNPILED | DCSSTSGFPT | QESFTMASCT | SESHSHWVHS | 
    297:
    PIECTELDLQ | KFSSSASYTG | AETLGGNTVE | STGDRLELNV | PFEVPSP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    SMR:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 27
    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 27
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 27
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 27
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 27
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 27
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 27
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 27
    Protein for Human Tumor necrosis factor receptor superfamily member 27
    Protein for Human Tumor necrosis factor receptor superfamily member 27

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors."
      Yan M. , Wang L.-C. , Hymowitz S.G. , Schilbach S. , Lee J. , Goddard A. , de Vos A.M. , Gao W.-Q. , Dixit V.M.
      Science290:523-527(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);MUTAGENESIS OF GLU-256;VARIANT ALA-129
      tissue: Fetal kidney.
    2. 2.
      "Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor."
      Sinha S.K. , Zachariah S. , Quinones H.I. , Shindo M. , Chaudhary P.M.
      J. Biol. Chem.277:44953-44961(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;VARIANT ALA-129
    3. 3.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3);VARIANT ALA-129
    4. 4.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ALA-129
      tissue: Brain.
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