Protein name:
Targeting protein for Xklp2 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts with AURKA.
Function:
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation.
Subcellular Location:
Nucleus
Cytoplasm
cytoskeleton
spindle
Cytoplasm
cytoskeleton
spindle pole
During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules.
Protein Attributes:
50:
MSQVTTSYSY | DAPTDFINFS | SLTDEEDMQH | IDSWFDEKAN | LENKFTGKDG |
100:
TGGLYQGKTP | LRKANLHRDV | TPLRPVDNTY | NKQAEKENLV | EESIPSNECP |
150:
SMKVKETTSR | NNPVQPQRRS | LRLSAKKNLE | QKEKQHVKMK | AKRCGTPVII |
200:
NEFPPSKKMK | VQKILKSTEE | QELEKRMKMQ | QEVVEMRKRN | EEFKKFALAG |
250:
AGQPVKKSVS | QVTKAVDFHF | RTDERVKQHP | KNQEEYKEVN | FTSELRKHPP |
300:
SPARVTKGCT | IVMPFNLSQG | KKRTFDETAS | TYVPLAQQVE | AFHKRTPTRY |
350:
HLRNRKDDIM | PLPSKSVVRI | CRDPQTPVLQ | TKHRTRPVTC | KSAADLEAEE |
400:
LEKQQQYKFK | AQELDPRILE | GGPILPKKPP | VKPPTQPVGF | DLEIEKRIQE |
450:
RESKKKLEEE | HYEFHSRPCP | TKILEDVVGV | PEKKELPITV | PKSPAFALKN |
500:
RIRMPTKEDK | EEEEPVMIRA | QPVPYFGMPF | KPQIPVGRTV | EVCPFSFDSR |
550:
DKERQLQKEK | KIKELQKGEV | PKFKAHPLPH | FDTINLPEKK | VKNTTQVEPF |
600:
CLETDRRGAL | KAQTWKHQLD | EELKQQKEAA | CFKARPNTVI | SQEPFVPKRE |
650:
KKSVIEGLSG | SLVQEPFQLA | TEKRAKERQE | LEKRMAEVEA | LKAQQLEEAR |
700:
QQEEEQQKEE | LARLRKELVH | KANPIRRYQG | VEVKSSDQPL | TVPVSPKFST |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Human
ELISA Kit for Bovine Targeting protein for Xklp2
ELISA Kit for Bovine Targeting protein for Xklp2
ELISA Kit for Bovine Targeting protein for Xklp2
CLIA Kit for Bovine Targeting protein for Xklp2
CLIA Kit for Bovine Targeting protein for Xklp2
CLIA Kit for Bovine Targeting protein for Xklp2
Polyclonal Antibody for Bovine Targeting protein for Xklp2
Polyclonal Antibody for Bovine Targeting protein for Xklp2
Polyclonal Antibody for Bovine Targeting protein for Xklp2
Monoclonal Antibody for Bovine Targeting protein for Xklp2
Monoclonal Antibody for Bovine Targeting protein for Xklp2
Monoclonal Antibody for Bovine Targeting protein for Xklp2
Protein for Bovine Targeting protein for Xklp2
Protein for Bovine Targeting protein for Xklp2
Protein for Bovine Targeting protein for Xklp2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Thymus .