Protein name:
Protein unc-13 homolog C ;
Alternative:
Munc13-3 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with STX1A and/or STX1B1, VAMP2 and SNAP25.
Function:
Probably plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Probably is involved in neurotransmitter release.
Subcellular Location:
Cytoplasm
Membrane
Peripheral membrane protein
Cell junction
synapse
presynaptic cell membrane
Peripheral membrane protein
Localized to presynaptic structures.
Protein Attributes:
50:
MVANFFKSLI | LPYIHKLCKG | MFTKKLGNTN | KNKEYRQQKK | DQDFPTAGQT |
100:
KSPKFSYTFK | STVKKIAKCS | STHNLSTEED | EASKEFSLSP | TFSYRVAIAN |
150:
GLQKNAKVTN | SDNEDLLQEL | SSIESSYSES | LNELRSSTEN | QAQSTHTMPV |
200:
RRNRKSSSSL | APSEGSSDGE | RTLHGLKLGA | LRKLRKWKKS | QECVSSDSEL |
250:
STMKKSWGIR | SKSLDRTVRN | PKTNALEPGF | SSSGCISQTH | DVMEMIFKEL |
300:
QGISQIETEL | SELRGHVNAL | KHSIDEISSS | VEVVQSEIEQ | LRTGFVQSRR |
350:
ETRDIHDYIK | HLGHMGSKAS | LRFLNVTEER | FEYVESVVYQ | ILIDKMGFSD |
400:
APNAIKIEFA | QRIGHQRDCP | NAKPRPILVY | FETPQQRDSV | LKKSYKLKGT |
450:
GIGISTDILT | HDIRERKEKG | IPSSQTYESM | AIKLSTPEPK | IKKNNWQSPD |
500:
DSDEDLESDL | NRNSYAVLSK | SELLTKGSTS | KPSSKSHSAR | SKNKTANSSR |
550:
ISNKSDYDKI | SSQLPESDIL | EKQTTTHYAD | ATPLWHSQSD | FFTAKLSRSE |
600:
SDFSKLCQSY | SEDFSENQFF | TRTNGSSLLS | SSDRELWQRK | QEGTATLYDS |
650:
PKDQHLNGGV | QGIQGQTETE | NTETVDSGMS | NGMVCASGDR | SHYSDSQLSL |
700:
HEDLSPWKEW | NQGADLGLDS | STQEGFDYET | NSLFDQQLDV | YNKDLEYLGK |
750:
CHSDLQDDSE | SYDLTQDDNS | SPCPGLDNEP | QGQWVGQYDS | YQGANSNELY |
800:
QNQNQLSMMY | RSQSELQSDD | SEDAPPKSWH | SRLSIDLSDK | TFSFPKFGST |
850:
LQRAKSALEV | VWNKSTQSLS | GYEDSGSSLM | GRFRTLSQST | ANESSTTLDS |
900:
DVYTEPYYYK | AEDEEDYTEP | VADNETDYVE | VMEQVLAKLE | NRTSITETDE |
950:
QMQAYDHLSY | ETPYETPQDE | GYDGPADDMV | SEEGLEPLNE | TSAEMEIRED |
1000:
ENQNIPEQPV | EITKPKRIRP | SFKEAALRAY | KKQMAELEEK | ILAGDSSSVD |
1050:
EKARIVSGND | LDASKFSALQ | VCGGAGGGLY | GIDSMPDLRR | KKTLPIVRDV |
1100:
AMTLAARKSG | LSLAMVIRTS | LNNEELKMHV | FKKTLQALIY | PMSSTIPHNF |
1150:
EVWTATTPTY | CYECEGLLWG | IARQGMKCLE | CGVKCHEKCQ | DLLNADCLQR |
1200:
AAEKSSKHGA | EDKTQTIITA | MKERMKIREK | NRPEVFEVIQ | EMFQISKEDF |
1250:
VQFTKAAKQS | VLDGTSKWSA | KITITVVSAQ | GLQAKDKTGS | SDPYVTVQVG |
1300:
KNKRRTKTIF | GNLNPVWDEK | FYFECHNSTD | RIKVRVWDED | DDIKSRVKQH |
1350:
FKKESDDFLG | QTIVEVRTLS | GEMDVWYNLE | KRTDKSAVSG | AIRLKINVEI |
1400:
KGEEKVAPYH | IQYTCLHENL | FHYLTEVKSN | GGVKIPEVKG | DEAWKVFFDD |
1450:
ASQEIVDEFA | MRYGIESIYQ | AMTHFSCLSS | KYMCPGVPAV | MSTLLANINA |
1500:
FYAHTTVSTN | IQVSASDRFA | ATNFGREKFI | KLLDQLHNSL | RIDLSKYREN |
1550:
FPASNTERLQ | DLKSTVDLLT | SITFFRMKVL | ELQSPPKASM | VVKDCVRACL |
1600:
DSTYKYIFDN | CHELYSQLTD | PSKKQDIPRE | DQGPTTKNLD | FWPQLITLMV |
1650:
TIIDEDKTAY | TPVLNQFPQE | LNMGKISAEI | MWTLFALDMK | YALEEHENQR |
1700:
LCKSTDYMNL | HFKVKWFYNE | YVRELPAFKD | AVPEYSLWFE | PFVMQWLDEN |
1750:
EDVSMEFLHG | ALGRDKKDGF | QQTSEHALFS | CSVVDVFAQL | NQSFEIIKKL |
1800:
ECPNPEALSH | LMRRFAKTIN | KVLLQYAAIV | SSDFSSHCDK | ENVPCILMNN |
1850:
IQQLRVQLEK | MFESMGGKEL | DSEASTILKE | LQVKLSGVLD | ELSVTYGESF |
1900:
QVIIEECIKQ | MSFELNQMRA | NGNTTSNKNS | AAMDAEIVLR | SLMDFLDKTL |
1950:
SLSAKICEKT | VLKRVLKELW | KLVLNKIEKQ | IVLPPLTDQT | GPQMIFIAAK |
2000:
DLGQLSKLKE | HMIREDARGL | TPRQCAIMEV | VLATIKQYFH | AGGNGLKKNF |
2050:
LEKSPDLQSL | RYALSLYTQT | TDALIKKFID | TQTSQSRSSK | DAVGQISVHV |
2100:
DITATPGTGD | HKVTVKVIAI | NDLNWQTTAM | FRPFVEVCIL | GPNLGDKKRK |
2150:
QGTKTKSNTW | SPKYNETFQF | ILGKENRPGA | YELHLSVKDY | CFAREDRIIG |
2200:
MTVIQLQNIA | EKGSYGAWYP | LLKNISMDET | GLTILRILSQ | RTSDDVAKEF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human Protein unc-13 homolog C
ELISA Kit for Human Protein unc-13 homolog C
ELISA Kit for Human Protein unc-13 homolog C
CLIA Kit for Human Protein unc-13 homolog C
CLIA Kit for Human Protein unc-13 homolog C
CLIA Kit for Human Protein unc-13 homolog C
Polyclonal Antibody for Human Protein unc-13 homolog C
Polyclonal Antibody for Human Protein unc-13 homolog C
Polyclonal Antibody for Human Protein unc-13 homolog C
Monoclonal Antibody for Human Protein unc-13 homolog C
Monoclonal Antibody for Human Protein unc-13 homolog C
Monoclonal Antibody for Human Protein unc-13 homolog C
Protein for Human Protein unc-13 homolog C
Protein for Human Protein unc-13 homolog C
Protein for Human Protein unc-13 homolog C
R&D Technical Data
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Precision
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Recovery
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Linearity
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : VARIANTS GLU-304 AND ALA-2196