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Index > Protein center > Xirp1(Gene name) > Mouse
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  • Xirp1 (Gene name),
  • Xin actin-binding repeat-containing protein 1 (Protein name ),  XIRP1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Xirp1(Cmya1;Xin);
    Protein name:
    Xin actin-binding repeat-containing protein 1;
    Alternative:
    Cardiomyopathy-associated protein 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with FLNC and VASP (By similarity). Interacts with F-actin and CTNNB1.
    Function:
    Protects actin filaments from depolymerization.
    Subcellular Location:
    Cell junction Colocalizes with actin stress fibers.
    Protein Attributes:
    Sequence length:
    1129
    Sequence:
    50:
    MADAQMQVAP | TPTIQMRTEE | DLSLPHPSAP | EGLPPPPPKE | TFSKFQQQRQ | 
    100:
    ASELRRLYKH | IHPELRKNLE | EAVAEDLAEV | LGSEEPTEGD | VQCMRWIFEN | 
    150:
    WRLDAIGDHE | RPAAREPVSG | GNVQATSRKF | EEGSFTNSSD | QEPEGLRPSG | 
    200:
    GDVQAARQMF | ETKPLDALRG | QEEATQTTMR | EPAATGDVQG | TRKLFETRPL | 
    250:
    DRLGSRPSIQ | EQSPLELRSE | IQELKGDVKK | TVKLFQTEPL | CAIQDAEGTI | 
    300:
    HEVKAACREE | IQSNAVRSAR | WLFETRPLDA | FNQDPSQVRV | IRGISLEEGA | 
    350:
    LPDVSATRWI | FETQPLDAIR | EIEVDEKDFQ | PSPDLIPPGP | DVQHQRHLFE | 
    400:
    TCSLDTLKGE | RETEAEVPPK | EEVIPGDVRS | TLWLFETKPL | DAFRDQVQVG | 
    450:
    HLQRVGHQEG | EGLVTECLPS | NGTSVLPLSQ | GVPQNDGLKG | DVKTFKNLFE | 
    500:
    TLPLDSIGQG | EPSAYGNINR | GQNTDSAEQS | QGSDAPVYAM | QDSRGQLHAL | 
    550:
    TSVSREQVVG | GDVQGYKWMF | ETQPLDTLGR | SPSTIDVVRG | ITRQEVVAGD | 
    600:
    VGTTRWLFET | QPLEMIHQQE | QQKPEEEEGK | GPGGPPPELP | KKGDVQTIRW | 
    650:
    LFETYPMSEL | AEKRESEVTD | PVSKAETQSC | TWMFGPQSLN | PAEGSGEQHL | 
    700:
    QTSQVPAGDR | QTDRHVFETE | SLPASNQSSG | RKPVRYCSRV | EIPSGQVSRQ | 
    750:
    KEVFQALEAG | KKEVPETTIN | LGSIPTGSVH | KFTWLFENCP | MGSLAAESIR | 
    800:
    GDNLQEEQPK | GSAGHGTPER | QETAAERTLR | TLHATPGILH | HGGILMEARG | 
    850:
    PGELCLAKYV | LPSPGQGRPY | IRKEELVCGE | LPRIVRQVLR | RTDVDQQGLL | 
    900:
    VQEDTAGQLQ | LHPLMLPGPG | DPGNIEDMDP | ELQQLLACGL | GVSVSKTGLV | 
    950:
    MQETGQGLVA | LTAYSLQPQL | TSRAPERSSV | QLLASCIDKG | DLHSLHSLRW | 
    1000:
    EPPTDPSSGP | ATEESQRVPP | TESIIHVTPL | DSTMEMGQLR | ISGSTPCPPP | 
    1050:
    SRAAGKVVLP | NGKPVAQAPL | QEARKKRDIS | HAGQKGKAAS | GRPEASPLGS | 
    1100:
    GAPDLQEAMQ | NLRLATAEAQ | SLHQQVLSRH | PQGSDPVATS | MPVQDVLQAS | 
    1129:
    TPATGVTQGS | IRPVAGSEAR | IPAVPRKLL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Xin actin-binding repeat-containing protein 1
    ELISA Kit for Mouse Xin actin-binding repeat-containing protein 1
    ELISA Kit for Mouse Xin actin-binding repeat-containing protein 1
    CLIA Kit for Mouse Xin actin-binding repeat-containing protein 1
    CLIA Kit for Mouse Xin actin-binding repeat-containing protein 1
    CLIA Kit for Mouse Xin actin-binding repeat-containing protein 1
    Polyclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
    Polyclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
    Polyclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
    Monoclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
    Monoclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
    Monoclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
    Protein for Mouse Xin actin-binding repeat-containing protein 1
    Protein for Mouse Xin actin-binding repeat-containing protein 1
    Protein for Mouse Xin actin-binding repeat-containing protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      tissue: Heart muscle.
    2. 2.
      Wang D.-Z. , Lin J.J.-C.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development."
      Sinn H.W. , Balsamo J. , Lilien J. , Lin J.J.-C.
      Dev. Dyn.225:1-13(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    5. 5.
      "Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects."
      Gustafson-Wagner E.A. , Sinn H.W. , Chen Y.-L. , Wang D.-Z. , Reiter R.S. , Lin J.L.-C. , Yang B. , Williamson R.A. , Chen J. , Lin C.-I. , Lin J.J.-C.
      Am. J. Physiol.293:H2680-H2692(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;TISSUE SPECIFICITY
    6. 6.
      "The intercalated disc protein, mXin{alpha}, is capable of interacting with beta-catenin and bundling actin filaments."
      Choi S. , Gustafson-Wagner E.A. , Wang Q. , Harlan S.M. , Sinn H.W. , Lin J.L.-C. , Lin J.J.-C.
      J. Biol. Chem.282:36024-36036(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CTNNB1 AND ACTIN
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