Gene name:
Xirp1(Cmya1;Xin);
Protein name:
Xin actin-binding repeat-containing protein 1;
Alternative:
Cardiomyopathy-associated protein 1;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with FLNC and VASP (By similarity). Interacts with F-actin and CTNNB1.
Function:
Protects actin filaments from depolymerization.
Subcellular Location:
Cell junction
Colocalizes with actin stress fibers.
Protein Attributes:
50:
MADAQMQVAP | TPTIQMRTEE | DLSLPHPSAP | EGLPPPPPKE | TFSKFQQQRQ |
100:
ASELRRLYKH | IHPELRKNLE | EAVAEDLAEV | LGSEEPTEGD | VQCMRWIFEN |
150:
WRLDAIGDHE | RPAAREPVSG | GNVQATSRKF | EEGSFTNSSD | QEPEGLRPSG |
200:
GDVQAARQMF | ETKPLDALRG | QEEATQTTMR | EPAATGDVQG | TRKLFETRPL |
250:
DRLGSRPSIQ | EQSPLELRSE | IQELKGDVKK | TVKLFQTEPL | CAIQDAEGTI |
300:
HEVKAACREE | IQSNAVRSAR | WLFETRPLDA | FNQDPSQVRV | IRGISLEEGA |
350:
LPDVSATRWI | FETQPLDAIR | EIEVDEKDFQ | PSPDLIPPGP | DVQHQRHLFE |
400:
TCSLDTLKGE | RETEAEVPPK | EEVIPGDVRS | TLWLFETKPL | DAFRDQVQVG |
450:
HLQRVGHQEG | EGLVTECLPS | NGTSVLPLSQ | GVPQNDGLKG | DVKTFKNLFE |
500:
TLPLDSIGQG | EPSAYGNINR | GQNTDSAEQS | QGSDAPVYAM | QDSRGQLHAL |
550:
TSVSREQVVG | GDVQGYKWMF | ETQPLDTLGR | SPSTIDVVRG | ITRQEVVAGD |
600:
VGTTRWLFET | QPLEMIHQQE | QQKPEEEEGK | GPGGPPPELP | KKGDVQTIRW |
650:
LFETYPMSEL | AEKRESEVTD | PVSKAETQSC | TWMFGPQSLN | PAEGSGEQHL |
700:
QTSQVPAGDR | QTDRHVFETE | SLPASNQSSG | RKPVRYCSRV | EIPSGQVSRQ |
750:
KEVFQALEAG | KKEVPETTIN | LGSIPTGSVH | KFTWLFENCP | MGSLAAESIR |
800:
GDNLQEEQPK | GSAGHGTPER | QETAAERTLR | TLHATPGILH | HGGILMEARG |
850:
PGELCLAKYV | LPSPGQGRPY | IRKEELVCGE | LPRIVRQVLR | RTDVDQQGLL |
900:
VQEDTAGQLQ | LHPLMLPGPG | DPGNIEDMDP | ELQQLLACGL | GVSVSKTGLV |
950:
MQETGQGLVA | LTAYSLQPQL | TSRAPERSSV | QLLASCIDKG | DLHSLHSLRW |
1000:
EPPTDPSSGP | ATEESQRVPP | TESIIHVTPL | DSTMEMGQLR | ISGSTPCPPP |
1050:
SRAAGKVVLP | NGKPVAQAPL | QEARKKRDIS | HAGQKGKAAS | GRPEASPLGS |
1100:
GAPDLQEAMQ | NLRLATAEAQ | SLHQQVLSRH | PQGSDPVATS | MPVQDVLQAS |
1129:
TPATGVTQGS | IRPVAGSEAR | IPAVPRKLL
Vaild Sequence:
Related Databases
Uniprot:
FOR
ELISA Kit for Mouse Xin actin-binding repeat-containing protein 1
ELISA Kit for Mouse Xin actin-binding repeat-containing protein 1
ELISA Kit for Mouse Xin actin-binding repeat-containing protein 1
CLIA Kit for Mouse Xin actin-binding repeat-containing protein 1
CLIA Kit for Mouse Xin actin-binding repeat-containing protein 1
CLIA Kit for Mouse Xin actin-binding repeat-containing protein 1
Polyclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
Polyclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
Polyclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
Monoclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
Monoclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
Monoclonal Antibody for Mouse Xin actin-binding repeat-containing protein 1
Protein for Mouse Xin actin-binding repeat-containing protein 1
Protein for Mouse Xin actin-binding repeat-containing protein 1
Protein for Mouse Xin actin-binding repeat-containing protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
-
1.
"Requirement of a novel gene, Xin, in cardiac morphogenesis."
Wang D.-Z.
,
Reiter R.S.
,
Lin J.L.-C.
,
Wang Q.
,
Williams H.S.
,
Krob S.L.
,
Schultheiss T.M.
,
Evans S.
,
Lin J.-J.
Development126:1281-1294(1999)
[
PubMed]
[
Europe PMC]
[
Abstract]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue:
Heart muscle.
-
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: SEQUENCE REVISION
-
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
-
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: DEVELOPMENTAL STAGE
-
5.
"Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects."
Gustafson-Wagner E.A.
,
Sinn H.W.
,
Chen Y.-L.
,
Wang D.-Z.
,
Reiter R.S.
,
Lin J.L.-C.
,
Yang B.
,
Williamson R.A.
,
Chen J.
,
Lin C.-I.
,
Lin J.J.-C.
Am. J. Physiol.293:H2680-H2692(2007)
[
PubMed]
[
Europe PMC]
[
Abstract]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: DISRUPTION PHENOTYPE;TISSUE SPECIFICITY
-
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: INTERACTION WITH CTNNB1 AND ACTIN