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Index > Protein center > Xkr8(Gene name) > Mouse
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  • Xkr8 (Gene name),
  • XK-related protein 8 (Protein name ),  XKR8_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Xkr8;
    Protein name:
    XK-related protein 8(mXkr8);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    401
    Sequence:
    50:
    MPLSVHHHVA | LDVVVGLVSI | LSFLLDLVAD | LWAVVQYVLL | GRYLWAALVL | 
    100:
    VLLGQASVLL | QLFSWLWLTA | DPTELHHSQL | SRPFLALLHL | LQLGYLYRCL | 
    150:
    HGMHQGLSMC | YQEMPSECDL | AYADFLSLDI | SMLKLFESFL | EATPQLTLVL | 
    200:
    AIVLQNGQAE | YYQWFGISSS | FLGISWALLD | YHRSLRTCLP | SKPRLGRSSS | 
    250:
    AIYFLWNLLL | LGPRICAIAL | FSAVFPYYVA | LHFFSLWLVL | LFWIWLQGTN | 
    300:
    FMPDSKGEWL | YRVTMALILY | FSWFNVSGGR | TRGRAVIHLI | FIFSDSVLLV | 
    350:
    TTSWVTHGTW | LPSGISLLMW | VTIGGACFFL | GLALRVIYYL | WLHPSCSWDP | 
    400:
    DLVDGTLGLL | SPHRPPKLIY | NRRATLLAEN | FFAKAKARAV | LTEEVQLNGV | 
    401:
    L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse mXkr8
    ELISA Kit for Mouse mXkr8
    CLIA Kit for Mouse mXkr8
    CLIA Kit for Mouse mXkr8
    Polyclonal Antibody for Mouse mXkr8
    Polyclonal Antibody for Mouse mXkr8
    Monoclonal Antibody for Mouse mXkr8
    Monoclonal Antibody for Mouse mXkr8
    Protein for Mouse mXkr8
    Protein for Mouse mXkr8

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "A superfamily of XK-related genes (XRG) widely expressed in vertebrates and invertebrates."
      Huang C.-H. , Chen Y.
      Submitted (2004-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6J.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Testis.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
    6. 6.
      "Xk-Related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells."
      Suzuki J. , Denning D.P. , Imanishi E. , Horvitz H.R. , Nagata S.
      Science341:403-406(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;DISRUPTION PHENOTYPE
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