Ovarian cancer is a common tumor in women, because the ovary is in the depths of the pelvic cavity, so early ovarian cancer often does not have obvious symptoms, generally diagnosed when it has been late, the mortality rate is higher. It is important to search for better early diagnostic indicators and new therapeutic targets.
The expression of prostate-associated antigen, or prostate acid phosphatase (PAP), has been found in many other epithelial tumors, including gastric cancer, colon cancer, and breast cancer. PAP is an enzyme synthesized by prostate epithelial cells, which is the main source of male serum acid phosphatase (APC) and an isoenzyme produced by lysosomes of prostate epithelial cells in APC. The prostate gland is the main source of this enzyme. PAP is a glycoprotein composed of 2 subunits, mainly distributed in urine and low in serum. Increased serum PAP is often used as the diagnostic criteria for prostate cancer. PAP has always been considered as a specific tumor marker of prostate cancer. According to the latest research, PAP also exists in the prostate and other tissues besides prostate cancer, so PAP is not an absolute tissue specific marker. In addition, the researchers confirmed the presence of prostate-associated antigen, or prostate acid phosphatase (PAP), in epithelial tissues of patients with a variety of cancers, but there has been no systematic study of PAP expression in ovarian cancer. Therefore, the researchers can use this as a starting point to test the expression level of PAP in the cancer cells and tumor tissues of ovarian cancer patients, and explore the possibility of PAP as the target for diagnosis and treatment of ovarian cancer, so as to provide further research basis for the diagnosis and treatment of ovarian cancer.
E0168r is a microwave band ELISA kit for the analysis of lysins and metalloproteinases 30(prostate acid phosphatase) in biological samples. The concentration gradient of the standard or positive control product gives the kit a theoretical detection range in biological study samples containing acid phosphatase of the prostate. The E0168r kit ELISA assay biochemical technique is based on the detection of the prostatic acid phosphatase antigen targets in the samples based on the acidic prostatic phosphatase antibody - acidic prostatic phosphatase antigen interaction (immunoadsorption) and HRP colorimetry system.
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