Protein name:
Angiopoietin-1 (ANG-1) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
Subcellular Location:
Secreted
Protein Attributes:
50:
MTVFLSFAFF | AAILTHIGCS | NQRRNPENGG | RRYNRIQHGQ | CAYTFILPEH |
100:
DGNCRESATE | QYNTNALQRD | APHVEPDFSS | QKLQHLEHVM | ENYTQWLQKL |
150:
ENYIVENMKS | EMAQIQQNAV | QNHTATMLEI | GTSLLSQTAE | QTRKLTDVET |
200:
QVLNQTSRLE | IQLLENSLST | YKLEKQLLQQ | TNEILKIHEK | NSLLEHKILE |
250:
MEGKHKEELD | TLKEEKENLQ | GLVSRQTFII | QELEKQLSRA | TNNNSILQKQ |
300:
QLELMDTVHN | LISLCTKEGV | LLKGGKREEE | KPFRDCADVY | QAGFNKSGIY |
350:
TIYFNNMPEP | KKVFCNMDVN | GGGWTVIQHR | EDGSLDFQRG | WKEYKMGFGN |
400:
PSGEYWLGNE | FIFAITSQRQ | YMLRIELMDW | EGNRAYSQYD | RFHIGNEKQN |
450:
YRLYLKGHTG | TAGKQSSLIL | HGADFSTKDA | DNDNCMCKCA | LMLTGGWWFD |
498:
ACGPSNLNGM | FYTAGQNHGK | LNGIKWHYFK | GPSYSLRSTT | MMIRPLDF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Pig
Bovine
Dog
ELISA Kit for Mouse ANG-1
ELISA Kit for Mouse ANG-1
ELISA Kit for Mouse ANG-1
ELISA Kit for Mouse ANG-1
ELISA Kit for Mouse ANG-1
ELISA Kit for Mouse ANG-1
Polyclonal Antibody for Mouse ANG-1
Polyclonal Antibody for Mouse ANG-1
Polyclonal Antibody for Mouse ANG-1
Polyclonal Antibody for Mouse ANG-1
Polyclonal Antibody for Mouse ANG-1
Polyclonal Antibody for Mouse ANG-1
Monoclonal Antibody for Mouse ANG-1
Monoclonal Antibody for Mouse ANG-1
Monoclonal Antibody for Mouse ANG-1
Monoclonal Antibody for Mouse ANG-1
Monoclonal Antibody for Mouse ANG-1
Monoclonal Antibody for Mouse ANG-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning."
Davis S.
,
Aldrich T.H.
,
Jones P.F.
,
Acheson A.
,
Compton D.L.
,
Jain V.
,
Ryan T.E.
,
Bruno J.
,
Radziejewski C.
,
Maisonpierre P.C.
,
Yancopoulos G.D.
Cell87:1161-1169(1996)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Embryo .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .