Gene name:
Angpt2 (Agpt2) ;
Protein name:
Angiopoietin-2 (ANG-2) ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Can induce tyrosine phosphorylation of TIE2. Binds to Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Subcellular Location:
Secreted
Protein Attributes:
50:
MWQIVFLTFG | CDLVLASAYN | NFRKSVDSTG | RRQYQVQNGP | CSYTFLLPET |
100:
DSCRSSSSPY | MSNAVQRDAP | LDYDDSVQRL | QVLENILENN | TQWLMKLENY |
150:
IQDNMKKEMV | EIQQNVVQNQ | TAVMIEIGTS | LLNQTAAQTR | KLTDVEAQVL |
200:
NQTTRLELQL | LQHSISTNKL | EKQILDQTSE | INKLQDKNSF | LEKKVLDMED |
250:
KHSVQLQSMK | EQKDQLQVLV | SKQSSVIDEL | EKKLVTATVN | NSVLQKQQHD |
300:
LMETVNSLLT | MMSSPDYKSS | VAVPKEEKTT | FRDCAEIFKS | GLTTSGIYTL |
350:
TFPNSTEEVK | AYCDMDMGGG | GWTVIQHRED | GSVDFQRTWK | EYKEGFGSPL |
400:
GEYWLGNEFV | SQLTSGHRYV | LKIQLKDWEG | SEAHSLYEHF | YLSGEESNYR |
450:
IHLTGLTGTA | GKISSISQPG | SDFSTKDSDN | DKCICKCSQM | LTGGWWFDAC |
496:
GPSNLNGQYY | PQKQNTNKFN | GIKWYYWKGS | GYSLKATTMM | IRPADF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Pig
Bovine
Dog
Polyclonal Antibody for Rat ANG-2
Polyclonal Antibody for Rat ANG-2
Polyclonal Antibody for Rat ANG-2
Polyclonal Antibody for Rat ANG-2
Polyclonal Antibody for Rat ANG-2
Polyclonal Antibody for Rat ANG-2
Monoclonal Antibody for Rat ANG-2
Monoclonal Antibody for Rat ANG-2
Monoclonal Antibody for Rat ANG-2
Monoclonal Antibody for Rat ANG-2
Monoclonal Antibody for Rat ANG-2
Monoclonal Antibody for Rat ANG-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
J Zhang, LB Li, Z Qiu, et al.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Kidney .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 340-476
strain :
Sprague-Dawley .
tissue :
Heart .
tissue :
Placenta .