CACNA1A ELISA Kit for Rabbit(Oryctolagus cuniculus) | EIAab.comCACNA1A ELISA Kit for Rabbit(Oryctolagus cuniculus)

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CACNA1A (Gene name),

Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Protein name ), CAC1A_RABIT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CACNA1A(CACH4;CACN3;CACNL1A4);

Protein name:

Voltage-dependent P/Q-type calcium channel subunit alpha-1A;

Alternative:

Calcium channel, L type, alpha-1 polypeptide isoform 4;Brain calcium channel I(BI);Voltage-gated calcium channel subunit alpha Cav2.1;

Organism:

Rabbit (Oryctolagus cuniculus).

General Annotation

Sub Unit:

Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity. Interacts with CABP1.

Function:

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin-IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DHP), and omega-conotoxin-GVIA (omega-CTx-GVIA).

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

2424

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RGGRRWTASA | GKGGGGPRAS | APSP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF08763

UniGene:

Ocu.2123

Uniprot:

P27884

FOR

ELISA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

E1344r

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96T

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ELISA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

ELISA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

E1344h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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ELISA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

ELISA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

E1344m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

U1344h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

U1344r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

CLIA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

CLIA Kit for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

U1344m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

P1344Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

P1344Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

P1344Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Monoclonal Antibody for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Protein for Rabbit Voltage-dependent P/Q-type calcium channel subunit alpha-1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Primary structure and functional expression from complementary DNA of a brain calcium channel."
Mori Y. , Friedrich T. , Kim M.-S. , Mikami A. , Nakai J. , Ruth P. , Bosse E. , Hofmann F. , Flockerzi V. , Furuichi T. , Mikoshiba K. , Imoto K. , Tanabe T. , Numa S.
Nature350:398-402(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING
tissue: Brain.
2.

"Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit."
Pragnell M. , de Waard M. , Mori Y. , Tanabe T. , Snutch T.P. , Campbell K.P.
Nature368:67-70(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BETA-SUBUNIT BINDING DOMAIN;MUTAGENESIS OF GLU-386; LEU-389; TYR-392 AND GLU-400
3.

"A hot spot for the interaction of gating modifier toxins with voltage-dependent ion channels."
Winterfield J.R. , Swartz K.J.
J. Gen. Physiol.116:637-644(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF GLU-188 AND GLU-1658

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