Efna2 ELISA Kit for Mouse(Mus musculus) | EIAab.comEfna2 ELISA Kit for Mouse(Mus musculus)

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Efna2 (Gene name),

Ephrin-A2 (Protein name ), EFNA2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Efna2(Elf1;Epl6;Eplg6;Lerk6);

Protein name:

Ephrin-A2;

Alternative:

ELF-1;CEK7-ligand(CEK7-L);EPH-related receptor tyrosine kinase ligand 6(LERK-6);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5. Interacts with EPHA8; activates EPHA8.

Function:

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.

Subcellular Location:

Cell membrane Lipid-anchor GPI-anchor

Protein Attributes:

Sequence length:

209

Sequence:

50:

100:

150:

200:

209:

PVLWSLLGS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00812

KEGG:

mmu:13637

STRING:

10090.ENSMUSP00000003154

UniGene:

Mm.1478

String:

P52801

SMR:

P52801

Uniprot:

P52801

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ELISA Kit for Mouse Ephrin-A2

Cat.:

E0301m

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Ephrin-A2

Cat.:

E0301h

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Manual:

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96T

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ELISA Kit for Mouse Ephrin-A2

Cat.:

E0301c

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Packing:

96T

CLIA Kit for Mouse Ephrin-A2

Cat.:

U0301h

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Packing:

96T

CLIA Kit for Mouse Ephrin-A2

Cat.:

U0301m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Ephrin-A2

Cat.:

U0301c

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96T

Polyclonal Antibody for Mouse Ephrin-A2

Cat.:

P0301Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Ephrin-A2

Cat.:

P0301Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Ephrin-A2

Monoclonal Antibody for Mouse Ephrin-A2

Protein for Mouse Ephrin-A2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases."
Cheng H.J. , Flanagan J.G.
Cell79:157-168(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Swiss Webster.
tissue: Brain.
2.

"cDNA cloning and characterization of a Cek7 receptor protein-tyrosine kinase ligand that is identical to the ligand (ELF-1) for the Mek-4 and Sek receptor protein-tyrosine kinases."
Shao H. , Lou L. , Pandey A. , Verderame M.F. , Siever D.A. , Dixit V.M.
J. Biol. Chem.270:3467-3470(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Limb.
4.

"The Eek receptor, a member of the Eph family of tyrosine protein kinases, can be activated by three different Eph family ligands."
Park S. , Sanchez M.P.
Oncogene14:533-542(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN EPHA8 ACTIVATION;INTERACTION WITH EPHA8
5.

"Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis."
Irie N. , Takada Y. , Watanabe Y. , Matsuzaki Y. , Naruse C. , Asano M. , Iwakura Y. , Suda T. , Matsuo K.
J. Biol. Chem.284:14637-14644(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN BONE REMODELING

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