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Index > Protein center > Havcr2(Gene name) > Mouse
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  • Havcr2 (Gene name),
  • Hepatitis A virus cellular receptor 2 homolog (Protein name ),  HAVR2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Havcr2(Tim3;Timd3);
    Protein name:
    Hepatitis A virus cellular receptor 2 homolog(HAVcr-2);
    Alternative:
    T-cell membrane protein 3(TIM-3);T-cell immunoglobulin and mucin domain-containing protein 3(TIMD-3);TIM-3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    281
    Sequence:
    50:
    MFSGLTLNCV | LLLLQLLLAR | SLENAYVFEV | GKNAYLPCSY | TLSTPGALVP | 
    100:
    MCWGKGFCPW | SQCTNELLRT | DERNVTYQKS | SRYQLKGDLN | KGDVSLIIKN | 
    150:
    VTLDDHGTYC | CRIQFPGLMN | DKKLELKLDI | KAAKVTPAQT | AHGDSTTASP | 
    200:
    RTLTTERNGS | ETQTLVTLHN | NNGTKISTWA | DEIKDSGETI | RTAIHIGVGV | 
    250:
    SAGLTLALII | GVLILKWYSC | KKKKLSSLSL | ITLANLPPGG | LANAGAVRIR | 
    281:
    SEENIYTIEE | NVYEVENSNE | YYCYVNSQQP | S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse HAVcr-2
    Cat.:
    E13657m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse HAVcr-2
    Cat.:
    E13657h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse HAVcr-2
    Cat.:
    E13657r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse HAVcr-2
    Cat.:
    U13657r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse HAVcr-2
    Cat.:
    U13657h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse HAVcr-2
    Cat.:
    U13657m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse HAVcr-2
    Cat.:
    P13657Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse HAVcr-2
    Cat.:
    P13657Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse HAVcr-2
    Cat.:
    P13657Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse HAVcr-2
    Monoclonal Antibody for Mouse HAVcr-2
    Monoclonal Antibody for Mouse HAVcr-2
    Protein for Mouse HAVcr-2
    Protein for Mouse HAVcr-2
    Protein for Mouse HAVcr-2

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    References
    1. 1.
      "Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family."
      McIntire J.J. , Umetsu S.E. , Akbari O. , Potter M. , Kuchroo V.K. , Barsh G.S. , Freeman G.J. , Umetsu D.T. , DeKruyff R.H.
      Nat. Immunol.2:1109-1116(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: DBA/2.
      tissue: Spleen.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease."
      Monney L. , Sabatos C.A. , Gaglia J.L. , Ryu A. , Waldner H. , Chernova T. , Manning S. , Greenfield E.A. , Coyle A.J. , Sobel R.A. , Freeman G.J. , Kuchroo V.K.
      Nature415:536-541(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
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