Gene name:
Havcr2 (Tim3;Timd3) ;
Protein name:
Hepatitis A virus cellular receptor 2 homolog (HAVcr-2) ;
Alternative:
T-cell membrane protein 3 (TIM-3) ;T-cell immunoglobulin and mucin domain-containing protein 3 (TIMD-3) ;TIM-3 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MFSGLTLNCV | LLLLQLLLAR | SLENAYVFEV | GKNAYLPCSY | TLSTPGALVP |
100:
MCWGKGFCPW | SQCTNELLRT | DERNVTYQKS | SRYQLKGDLN | KGDVSLIIKN |
150:
VTLDDHGTYC | CRIQFPGLMN | DKKLELKLDI | KAAKVTPAQT | AHGDSTTASP |
200:
RTLTTERNGS | ETQTLVTLHN | NNGTKISTWA | DEIKDSGETI | RTAIHIGVGV |
250:
SAGLTLALII | GVLILKWYSC | KKKKLSSLSL | ITLANLPPGG | LANAGAVRIR |
281:
SEENIYTIEE | NVYEVENSNE | YYCYVNSQQP | S
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Mouse HAVcr-2
ELISA Kit for Mouse HAVcr-2
ELISA Kit for Mouse HAVcr-2
CLIA Kit for Mouse HAVcr-2
CLIA Kit for Mouse HAVcr-2
CLIA Kit for Mouse HAVcr-2
Polyclonal Antibody for Mouse HAVcr-2
Polyclonal Antibody for Mouse HAVcr-2
Polyclonal Antibody for Mouse HAVcr-2
Monoclonal Antibody for Mouse HAVcr-2
Monoclonal Antibody for Mouse HAVcr-2
Monoclonal Antibody for Mouse HAVcr-2
Protein for Mouse HAVcr-2
Protein for Mouse HAVcr-2
Protein for Mouse HAVcr-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
DBA/2 .
tissue :
Spleen .
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
3.
"Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease."
Monney L.
,
Sabatos C.A.
,
Gaglia J.L.
,
Ryu A.
,
Waldner H.
,
Chernova T.
,
Manning S.
,
Greenfield E.A.
,
Coyle A.J.
,
Sobel R.A.
,
Freeman G.J.
,
Kuchroo V.K.
Nature415:536-541(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY