Hspa1a ELISA Kit for Rat(Rattus norvegicus) | EIAab.comHspa1a ELISA Kit for Rat(Rattus norvegicus)

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Hspa1a (Gene name),

Heat shock 70 kDa protein 1A (Protein name ), HSP71_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

Hspa1a;

Protein name:

Heat shock 70 kDa protein 1A;

Alternative:

HSP70-1;Heat shock 70 kDa protein 1;HSP70.1;

Organism:

Hspa1a (Rattus norvegicus).

General Annotation

Sub Unit:

Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with IRAK1BP1, TSC2 and DNAAF2. Component of a complex composed at least of CATSPER1, CATSPERB, CATSPERG and HSPA1B (By similarity). Interacts with TERT; the interaction occurs in the absence of the RNA component, TERC, and dissociates once the TERT complex has formed (By similarity). Interacts with CHCHD3.

Function:

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.

Subcellular Location:

Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Protein Attributes:

Sequence length:

641

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

641:

RVCNPIISGL | YQGAGAPGAG | GFGAQAPKGG | SGSGPTIEEV | D

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q07439

STRING:

10116.ENSRNOP00000050605

String:

Q07439

Pfam:

PF00012

KEGG:

rno:24472

UniGene:

Rn.1950

Uniprot:

P0DMW0

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ELISA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

E0873p

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96T

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ELISA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

E0873m

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96T

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ELISA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

E0873b

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96T

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ELISA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

E0873r

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96T

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ELISA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

E0873h

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96T

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CLIA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

U0873h

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96T

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CLIA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

U0873r

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96T

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CLIA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

U0873b

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Packing:

96T

CLIA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

U0873m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat Heat shock 70 kDa protein 1A

Cat.:

U0873p

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Looking for manual.

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96T

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Polyclonal Antibody for Rat Heat shock 70 kDa protein 1A

Cat.:

P0873Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Heat shock 70 kDa protein 1A

Cat.:

P0873Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat Heat shock 70 kDa protein 1A

Cat.:

P0873Rb-r

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40ug/0.2ml

Monoclonal Antibody for Rat Heat shock 70 kDa protein 1A

Protein for Rat Heat shock 70 kDa protein 1A

Cat.:

R0873h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Rat Heat shock 70 kDa protein 1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

12% SDS-PAGE analysis

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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Citations

[1].

"Proteomic analysis reveals significant elevation of heat shock protein 70 in patients with chronic heart failure due to arrhythmogenic right ventricul"

Ying-Jie Wei, Yin-Xia Huang, Ya Shen, Chuan-Jue Cui, Xiao-Ling Zhang, Hao Zhang, Sheng-Shou Hu

From:Molecular and Cellular Biochemistry

References

1.

"cDNA cloning and expression of stress-inducible rat hsp70 in normal and injured rat brain."
Longo F.M. , Wang S. , Narasimhan P. , Zhang J.S. , Chen J. , Massa S.M. , Sharp F.R.
J. Neurosci. Res.36:325-335(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"Comparative analysis of the three major histocompatibility complex-linked heat shock protein 70 (Hsp70) genes of the rat."
Walter L. , Rauh F. , Guenther E.
Immunogenetics40:325-330(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: LEW.1W/GUN.
3.

"Cloning, nucleotide sequence and expression of rat heat inducible hsp70 gene."
Lisowska K. , Krawczyk Z. , Widlak W. , Wolniczek P. , Wisniewski J.
Biochim. Biophys. Acta1219:64-72(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: Sprague-Dawley.
tissue: Liver.
4.

"Isolation of a novel inducible rat heat shock protein (HSP70) gene and its expression during ischaemia/hypoxia and heat shock."
Mestril R. , Chi S.H. , Sayen M.R. , Dillmann W.H.
Biochem. J.298:561-569(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: Wistar.
tissue: Spleen.
5.

"The genomic sequence and comparative analysis of the rat major histocompatibility complex."
Hurt P. , Walter L. , Sudbrak R. , Klages S. , Mueller I. , Shiina T. , Inoko H. , Lehrach H. , Guenther E. , Reinhardt R. , Himmelbauer H.
Genome Res.14:631-639(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: Brown Norway.

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